Single or repeated electroconvulsive shocks alter the levels of prodynorphin and proenkephalin mRNAs in rat brain

Statistical principles in experimental design.

1962 • 27,228 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I

1966 • 5,429 citations

Opioid Peptides May Excite Hippocampal Pyramidal Neurons by Inhibiting Adjacent Inhibitory Interneurons

1979 • 610 citations

Rat brain preproenkephalin mRNA. cDNA cloning, primary structure, and distribution in the central nervous system.

1984 • 540 citations

Sequence and expression of the rat prodynorphin gene.

1985 • 382 citations

Localization of enkephalin‐like immunoreactivity to identified axonal and neuronal populations of the rat hippocampus

1981 • 357 citations

Dynorphin is contained within hippocampal mossy fibers: immunochemical alterations after kainic acid administration and colchicine-induced neurotoxicity.

1983 • 289 citations

Determination of methionine enkephalin in discrete regions of rat brain

1977 • 280 citations

Vasopressin mRNA regulation in individual hypothalamic nuclei: a northern and in situ hybridization analysis

1986 • 184 citations

Repeated electroconvulsive shocks and the brain content of endorphins

1979 • 179 citations

Differential regulation of neuropeptide and proto-oncogene mRNA content in the hippocampus following recurrent seizures

1987 • 168 citations

Coordinate Expression of Hypothalamic Pro-Dynorphin and Pro-Vasopressin mRNAs with Osmotic Stimulation

1986 • 131 citations

Kainic acid alters the metabolism of Met5-enkephalin and the level of dynorphin A in the rat hippocampus

1986 • 114 citations

Reflex splanchnic nerve stimulation increases levels of proenkephalin A mRNA and proenkephalin A-related peptides in the rat adrenal medulla.

1986 • 112 citations

Opiate-like effects of electroconvulsive shock in rats: A differential effect of naloxone on nociceptive measures

1980 • 91 citations

Dynorphin- and enkephalin-like immunoreactivity is altered in limbic-basal ganglia regions of rat brain after repeated electroconvulsive shock.

1986 • 82 citations

Dynorphin- and enkephalin-like immunoreactivity is altered in limbic- basal ganglia regions of rat brain after repeated electroconvulsive shock

1986 • 75 citations

Amygdaloid kindling increases enkephalin-like immunoreactivity but decreases dynorphin-A-like immunoreactivity in rat hippocampus

1986 • 74 citations

Repeated electroconvulsive shock (ECS) and morphine tolerance: Demonstration of cross-sensitivity in the rat

1981 • 71 citations

Effects of enkephalin, morphine, and naloxone on the electrical activity of the in vitro hippocampal slice preparation

1981 • 69 citations

The opiate antagonist naloxone modifies the effects of electroconvulsive shock (ECS) on respiration, blood pressure and heart rate

1979 • 65 citations

Changes in the dynamic state of brain proenkephalin‐derived peptides during amygdaloid kindling

1986 • 58 citations

Levels of prodynorphin mRNA in rat dentate gyrus are decreased during hippocampal kindling

1987 • 51 citations

cellular responses to electrophoretically applied dynorphin in the rat hippocampus

1982 • 49 citations

Opiate-like electroencephalographic and behavioral effects of electroconvulsive shock in rats

1981 • 49 citations

Selective inactivation of opioid receptors in rat hippocampus demonstrates that dynorphin-A and -B may act on μ-receptors in the CA1 region

1985 • 47 citations

Regulation of opioid peptide synthesis and processing in adrenal chromaffin cells by catecholamines and cyclic adenosine 3':5'- monophosphate

1984 • 39 citations

Pulse-chase studies of the POMC/Beta-endorphin system in the pituitary of acutely and chronically stressed rats

1982 • 32 citations

Effects of dynorphin A (1–17), dynorphin A (1–13) and D-ala2-D-leu5-enkephalin on the excitability of pyramidal cells in CA1 and CA2 of the rat hippocampus

1984 • 28 citations

EEG, EMG and behavioral evidence for the involvement of endorphin systems in postictal events after electroconvulsive shock in rats

1982 • 25 citations

Stimulation of the perforant path alters hippocampal levels of opioid peptides, glutamine and GABA

1987 • 20 citations