Structural Basis of the Redox Switch in the OxyR Transcription Factor

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

Free radicals in biology and medicine

1991 • 17,840 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Automated MAD and MIR structure solution

1999 • 3,079 citations

Free radicals in biology and medicine

1985 • 2,999 citations

Requirement for Generation of H ₂ O ₂ for Platelet-Derived Growth Factor Signal Transduction

1995 • 2,505 citations

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1997 • 1,724 citations

Activation of the OxyR Transcription Factor by Reversible Disulfide Bond Formation

1998 • 1,162 citations

Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°

1991 • 1,109 citations

Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium

1985 • 1,025 citations

Reversible Inactivation of Protein-tyrosine Phosphatase 1B in A431 Cells Stimulated with Epidermal Growth Factor

1998 • 968 citations

Specific and Reversible Inactivation of Protein Tyrosine Phosphatases by Hydrogen Peroxide: Evidence for a Sulfenic Acid Intermediate and Implications for Redox Regulation

1998 • 933 citations

An essential role for free radicals and derived species in signal transduction

1997 • 909 citations

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

1990 • 869 citations

Crystal Structure of the Lactose Operon Repressor and Its Complexes with DNA and Inducer

1996 • 781 citations

Fas-Induced Caspase Denitrosylation

1999 • 742 citations

Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol—disulfide status

1999 • 561 citations

[25] Ribbons

1997 • 511 citations

Chaperone Activity with a Redox Switch

1999 • 509 citations

OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins.

1989 • 415 citations

Redox-dependent shift of OxyR-DNA contacts along an extended DNA-binding site: A mechanism for differential promoter selection

1994 • 379 citations

Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer

1996 • 376 citations

Crystal structure of a novel human peroxidase enzyme at 2.0 Å resolution

1998 • 370 citations

Crystal Structure of LacI Member, PurR, Bound to DNA: Minor Groove Binding by α Helices

1994 • 369 citations

[28] Phase determination from multiwavelength anomalous diffraction measurements

1997 • 355 citations

Nitrosative Stress: Activation of the Transcription Factor OxyR

1996 • 351 citations

Ionisation of Cysteine Residues at the Termini of Model α-Helical Peptides. Relevance to Unusual Thiol pKaValues in Proteins of the Thioredoxin Family

1995 • 314 citations

Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping

1995 • 290 citations

Mutational analysis of the redox-sensitive transcriptional regulator OxyR: regions important for oxidation and transcriptional activation

1995 • 245 citations

Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization

1998 • 152 citations

Mutational analysis of the redox-sensitive transcriptional regulator OxyR: regions important for DNA binding and multimerization

1995 • 127 citations

The structure of the cofactor-binding fragment of the LysR family member, CysB: a familiar fold with a surprising subunit arrangement

1997 • 120 citations

Evolution of a Protein Fold in Vitro

1999 • 112 citations

A Protein Phosphorylation Switch at the Conserved Allosteric Site in GP

1996 • 87 citations

Involvement of the RNA polymerase α subunit C‐terminal region in co‐operative interaction and transcriptional activation with OxyR protein

1993 • 72 citations

Multidegenerate DNA recognition by the OxyR transcriptional regulator.

1992 • 69 citations

In vivo oxidation‐reduction kinetics of OxyR, the transcriptional activator for an oxidative stress‐inducible regulon in Escherichia coli

1999 • 49 citations

The Amino-Terminal 100 Residues of the Nitrogen Assimilation Control Protein (NAC) Encode All Known Properties of NAC from Klebsiella aerogenes and Escherichia coli

1999 • 16 citations