Tumour necrosis factor-like activity on paraformaldehyde-fixed monocyte monolayers.

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

1986 • 1,439 citations

A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes

1986 • 1,282 citations

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1985 • 1,240 citations

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1985 • 1,125 citations

Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors.

1985 • 922 citations

Human tumor necrosis factor. Production, purification, and characterization.

1985 • 922 citations

Stimulation of neutrophils by tumor necrosis factor.

1986 • 847 citations

Interleukin 1, a potential regulator of fibroblast proliferation.

1982 • 835 citations

Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors.

1986 • 674 citations

Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor

1985 • 633 citations

Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.

1986 • 632 citations

Identification of a membrane-associated interleukin 1 in macrophages.

1985 • 487 citations

Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor

1985 • 464 citations

Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro.

1986 • 398 citations

Human interleukin 1 is a cytocidal factor for several tumor cell lines.

1985 • 380 citations

Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages.

1986 • 360 citations

Intracellular localization of human monocyte associated interleukin 1 (IL 1) activity and release of biologically active IL 1 from monocytes by trypsin and plasmin.

1986 • 318 citations

Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor

1985 • 240 citations

Recombinant interleukin 1 suppresses lipoprotein lipase activity in 3T3-L1 cells.

1985 • 235 citations

Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.

1978 • 206 citations

Mediation of mouse natural cytotoxic activity by tumour necrosis factor

1986 • 117 citations

Immunocytochemical detection of interleukin 1 within stimulated human monocytes.

1986 • 105 citations

The Induction of Cytolytic T Lymphocytes with Purified Plasma Membranes

1978 • 81 citations

Human Monocyte-mediated Cytotoxicity to K-562 Cells: Activation by Lymphokines

1979 • 63 citations

Inhibition of nonspecific tumoricidal activity by activated macrophages with antiserum against a soluble cytotoxic factor

1981 • 62 citations

Specificity of In Vivo Tumor Rejection Assessed by Mixing Immune Spleen Cells with Target and Unrelated Tumor Cells

1973 • 56 citations

Effect of human monocyte killing of tumour cells of antibody raised against an extracellular monocyte cytotoxin.

1983 • 42 citations

IFN-γ-induced production of monocyte cytotoxic factor

1985 • 26 citations

Purification of Cytostatic Protein Factors Released from Human Monocytes

1984 • 21 citations

Role of monocyte cytotoxic factor in cytolysis of actinomycin D-treated WEHI 164 cells mediated by freshly isolated human adherent mononuclear blood cells.

1986 • 19 citations

The role of monocyte cytotoxic factor in monocyte-mediated lysis of tumour cells.

1986 • 13 citations