Effect of ribavirin on virus load and quasispecies distribution in patients infected with hepatitis C virus

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

Avoiding false positives with PCR

1989 • 3,564 citations

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

Classification of chronic hepatitis: Diagnosis, grading and staging

1994 • 2,506 citations

Lassa Fever

1986 • 955 citations

Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay

1993 • 703 citations

Tolerance and efficacy of oral ribavirin treatment of chronic hepatitis C: A multicenter trial

1997 • 384 citations

Quantitative analysis of hepatitis C virus RNA in serum during interferon alfa therapy

1993 • 381 citations

Ribavirin as Therapy for Chronic Hepatitis C

1995 • 330 citations

Ribavirin treatment for chronic hepatitis C

1991 • 305 citations

A pilot study of combination therapy with ribavirin plus interferon alfa for interferon alfa-resistant chronic hepatitis C

1994 • 292 citations

A pilot study of ribavirin therapy for chronic hepatitis C

1992 • 291 citations

Biochemistry and clinical applications of ribavirin

1986 • 255 citations

Long-term efficacy of ribavirin plus interferon alfa in the treatment of chronic hepatitis C

1996 • 253 citations

Effect of interferon alfa on the dynamics of hepatitis C virus turnoverin vivo

1996 • 230 citations

Quantitative detection of hepatitis C virus RNA with a solid-phase signal amplification method: definition of optimal conditions for specimen collection and clinical application in interferon-treated patients.

1994 • 193 citations

RIBAVIRIN SMALL-PARTICLE AEROSOL TREATMENT OF INFLUENZA

1981 • 188 citations

Short-term prednisone therapy affects aminotransferase activity and hepatitis C virus RNA levels in chronic hepatitis C

1994 • 173 citations

Quantitative detection of hepatitis C virus RNA with a solid-phase signal amplification method: Definition of optimal conditions for specimen collection and clinical application in interferon-treated patients

1994 • 150 citations

Inhibition of immune functions by antiviral drugs.

1991 • 137 citations

Discrepancy between biochemical and virological responses to interferon-$alpha; in chronic hepatitis C

1993 • 133 citations

Phylogenetic analysis of hepatitis C virus isolates and their correlation to viremia, liver function tests, and histolog

1996 • 127 citations

Fluctations in viral load (HCV RNA) are relatively insignificant in untreated patients with chronic HCV infection

1996 • 127 citations

Ribavirin as Therapy for Chronic Hepatitis C

1995 • 95 citations

Comparison of two quantitative hepatitis C virus reverse transcriptase PCR assays

1996 • 80 citations

Effect of interferon alfa on the dynamics of hepatitis C virus turnover in vivo

1996 • 68 citations

Serum hepatitis C virus RNA level as a predictor of subsequent response to interferon‐α therapy in Japanese patients with chronic hepatitis C

1994 • 59 citations

Evaluation and comparison of different hepatitis C virus genotyping and serotyping assays

1997 • 41 citations

Quantification of Hepatitis C Virus RNA by Competitive Reverse Transcription and Polymerase Chain Reaction Using a Modified Hepatitis C Virus RNA Transcript

1995 • 36 citations

Modulation of hepatitis C virus quasispecies heterogeneity by interferon‐α and ribavirin therapy

1997 • 30 citations

Non-isotopic detection of hepatitis C virus quasispecies by single strand conformation polymorphism

1997 • 24 citations