Copper in brain

Superoxide Dismutase

1969 • 12,578 citations

PROGRESSIVE LENTICULAR DEGENERATION: A FAMILIAL NERVOUS DISEASE ASSOCIATED WITH CIRRHOSIS OF THE LIVER

1912 • 1,117 citations

Superoxide, hydrogen peroxide, and singlet oxygen in lipid peroxidation by a xanthine oxidase system.

1975 • 969 citations

Metallothionein: a Cadmium- and Zinc-containing Protein from Equine Renal Cortex

1960 • 965 citations

A sex-linked recessive disorder with retardation of growth, peculiar hair, and focal cerebral and cerebellar degeneration.

1962 • 839 citations

The Possible Significance of the Ferrous Oxidase Activity of Ceruloplasmin in Normal Human Serum

1966 • 672 citations

Menkes's kinky hair syndrome. An inherited defect in copper absorption with widespread effects.

1972 • 550 citations

The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to alpha-aminoadipic-delta-semialdehyde (allysine) by an extract from bone.

1968 • 488 citations

Investigations in Serum Copper. II. Isolation of the Copper Containing Protein, and a Description of some of its Properties.

1948 • 465 citations

MENKES'S KINKY HAIR SYNDROME

1972 • 397 citations

Synaptic vesicles in sympathetic neurons.

1971 • 357 citations

Copper homeostasis in the mammalian system.

1973 • 342 citations

High Density Lipoproteins and Atherosclerosis

1980 • 331 citations

Studies on cytochrome oxidase. Interactions of the cytochrome oxidase protein with phospholipids and cytochrome c.

1975 • 294 citations

The State and Function of Copper in Biological Systems

1970 • 246 citations

High-Density Lipoproteins and Atherosclerosis

1978 • 230 citations

Reactivation in vitro of zinc-requiring apo-enzymes by rat liver zinc-thionein

1980 • 230 citations

The State of Copper in Human Serum: Evidence for an Amino Acid-bound Fraction *

1967 • 229 citations

Connective Tissue Defect in the Chick Resulting from Copper Deficiency.

1961 • 186 citations

Physical and Chemical Studies on Ceruloplasmin

1970 • 183 citations

COPPER DEFICIENCY IN THE DEVELOPING RAT BRAIN: A POSSIBLE MODEL FOR MENKES’ STEELY‐HAIR DISEASE

1974 • 183 citations

On the sensitivity of metallothioneins to oxidation during isolation

1980 • 155 citations

Connective tissue amine oxidase II. Purification and partial characterization of lysyl oxidase from chick aorta

1974 • 146 citations

The inhibition of lipid autoxidation by human caeruloplasmin

1977 • 142 citations

Trichopoliodystrophy

1972 • 140 citations

Isolation of Human Hepatocuprein and Cerebrocuprein

1969 • 127 citations

Copper-thionein from fetal bovine liver

1977 • 121 citations

Benzylamine oxidase and histaminase: purification and crystallization of an enzyme from pig plasma

1964 • 115 citations

Distribution of metal ions in the subcellular fractions of several rat brain areas

1976 • 112 citations

ENZYMIC ACTIVITIES AND SODIUM, POTASSIUM AND COPPER CONCENTRATIONS IN MOUSE BRAIN AND LIVER AFTER CUPRIZONE TREATMENT IN VIVO

1973 • 106 citations

THE DISTRIBUTION OF COPPER IN HUMAN BRAIN

1960 • 99 citations

Evidence for ceruloplasmin as a copper transport protein

1975 • 95 citations

The Amino Acid Sequence of Peptide (1–24) of Rat and Human Serum Albumins

1969 • 93 citations

The protective action of superoxide dismutase on metal-ion catalysed peroxidation of phospholipids

1977 • 86 citations

Copper monooxygenases:tyrosinase and dopamine β-monooxygenase

1981 • 86 citations

Copper-induced activation of aortic lysyl oxidase in vivo.

1976 • 83 citations

Neural Lesions in the Offspring of Female Rats Fed α Copper-deficient Diet

1969 • 83 citations

CEREBROCUPREIN I. A COPPER‐CONTAINING PROTEIN ISOLATED FROM BRAIN

1957 • 81 citations

Copper Deficiency in the Guinea Pig

1967 • 76 citations

EFFECT OF COPPER DEFICIENCY ON THE CONCENTRATIONS OF CATECHOLAMINES AND RELATED ENZYME ACTIVITIES IN THE RAT BRAIN

1977 • 74 citations

THE PHYSIOLOGY OF COPPER IN MAN AND ITS RELATION TO WILSON'S DISEASE

1967 • 74 citations

Presence of norepinephrine and related enzymes in isolated brain microvessels.

1975 • 71 citations

Identification and Purification of a Non-Ceruloplasmin Ferroxidase of Human Serum

1970 • 65 citations

Proof for the Ascorbate Oxidase Activity of Ceruloplasmin

1964 • 65 citations

CARDIOVASCULAR STUDIES ON COPPER-DEFICIENT SWINE. V. THE HISTOGENESIS OF THE CORONARY ARTERY LESIONS.

1963 • 63 citations

COPPER DEFICIENCY AND THE CENTRAL NERVOUS SYSTEM

1974 • 63 citations

Association of histamine with cerebral microvessels in regions of bovine brain

1979 • 55 citations

Enzootic Ataxia of Lambs in Western Australia

1932 • 53 citations

Induction of lysyl oxidase with copper. Properties of an in vitro system.

1979 • 53 citations

An investigation of the copper site(s) of dopamine-β-hydroxylase by electron paramagnetic resonance

1977 • 53 citations

CERULOPLASMIN IN HEALTH AND DISEASE*

1961 • 53 citations

The determination of Cu, Zn, and Mn in subcellular rat liver fractions

1977 • 52 citations

Dopamine and Norepinephrine in Discrete Areas of the Copper‐Deficient Rat Brain¹

1980 • 49 citations

EFFECT OF COPPER STATUS ON BRAIN NEUROTRANSMITTER METABOLISM IN THE LAMB

1976 • 47 citations

Distribution of superoxide dismutase in rat brain

1976 • 46 citations

Hereditary hypoceruloplasminemia

1979 • 46 citations

Regulation of cadmium(2+)/zinc(2+)-stimulated metallothionein synthesis during induction, deinduction, and superinduction

1980 • 39 citations

Electron Paramagnetic Resonance of the Copper in Dopamine β‐Monooxygenase

1980 • 38 citations

COPPER DEFICIENCY IN THE RAT EFFECT ON SYNTHESIS OF PHOSPHOLIPIDS

1971 • 36 citations

Tetrazolium oxidase and superoxide dismutase: Evidence for identity

1973 • 34 citations

Regional and subcellular distribution of superoxide dismutase in brain

1976 • 32 citations

Copper Supplementation in Quaking Mutant Mice: Reduced Tremors and Increased Brain Copper

1976 • 32 citations

The Amine Oxidase of Pig Plasma in Copper Deficiency

1965 • 32 citations

Proteolysis of Human Ceruloplasmin

1979 • 32 citations

Absorption, transport and tissue storage of essential trace elements

1981 • 31 citations

Spectrophotometric determination of copper with N,N,N′,N′-tetraethylthiuram disulfide and an application of this method for studies on subcellular distribution of copper in rat brain

1970 • 31 citations

SUPEROXIDE DISMUTASE OF MAMMALIAN NERVOUS SYSTEM

1975 • 30 citations

Trace element binding in the copper deficient mottled mutants in the mouse

1979 • 30 citations

Interaction of dimethyl-p-phenylenediamine with ceruloplasmin

1967 • 28 citations

Serum dopamine-β-hydroxylase as an indicator of sympathetic activity and primary hypertension

1976 • 28 citations

The effect of copper excess on iron metabolism in sheep

1978 • 27 citations

COPPER BINDING AT PNS NODES OF RANVIER DURING DEMYELINATION AND REMYELINATION IN THE PERINEURIAL WINDOW

1976 • 27 citations

A study of the copper-binding proteins in liver and kidney tissue of neonatal normal and mottled mutant mice

1979 • 26 citations

Evidence for Uptake of Nonceruloplasminic Copper in the Brain: Effect of Ionic Copper and Amino Acids

1978 • 25 citations

Cadmium accumulation and distribution in human lung fibroblasts

1980 • 25 citations

On the amphiphilic and hydrophilic forms of dopamine β‐mono‐oxygenase in bovine adrenal medulla

1979 • 25 citations

The Biochemistry of Dyskinesias

1967 • 24 citations

Small copper-binding proteins from normal and copper-loaded liver☆

1975 • 23 citations

Isolation of a non-thionein copper-binding protein from liver of copper-injected rats

1977 • 23 citations

Neonatal hepatic mitochondrocuprein

1971 • 22 citations

Two copper-containing proteins from white and gray matter of brain

1977 • 21 citations

A copper-binding immunoglobulin from a myeloma patient. Studies of the copper-binding site.

1978 • 17 citations

A NEUROCHEMICAL STUDY OF FIELD CASES OF THE DELAYED SPINAL FORM OF SWAYBACK (ENZOOTICATAXIA) IN LAMBS

1974 • 17 citations

Two New Copper Proteins from Human Brain Isolation and Properties*

1971 • 16 citations

CYTOCHROMES IN BRAIN MITOCHONDRIA FROM LAMBS WITH ENZOOTIC ATAXIA

1976 • 16 citations

Neonatal hepatic mitochondrocuprein. III. Solubilization of the copper and protein from mitochondria of newborn liver by reduction with mercaptoethanol

1968 • 14 citations

Trace elements in embryonic development.

1968 • 14 citations

SUPEROXIDE DISMUTASE IN JUVENILE NEURONAL CEROID-LIPOFUSCINOSIS (SPIELMEYER-VOGT-BATTEN'S DISEASE)

1978 • 13 citations

An extremely acidic copper-containing protein from chromaffin granules

1981 • 12 citations

Ferroxidase II. The essential role of copper in enzymatic activity

1981 • 11 citations

Interaction of neurocuprein with adrenaline

1979 • 7 citations

Changes in the State of Ionization of Carboxyl Groups in Elastin in Response to the Binding of Sodium Dodecyl Sulfate

1978 • 7 citations

CIRCULATING DOPAMINE-?-HYDROXYLASE (D?H) AND CATECHOLAMINES IN A PAEDIATRIC PHAEOCHROMOCYTOMA

1976 • 6 citations

Properties of partially purified bovine brain dopamine β-hydroxylase

1978 • 4 citations

On ortho-diphenol oxidase activity of dopamine-β-monooxygenase

1982 • 4 citations

Frationation of brain copper proteins.

1956 • 4 citations

Copper- and Zinc-Binding Protein Fractions in the Soluble Cytoplasm of Rat Tissues

1977 • 1 citations

[Superoxide dismutase from brain white substance].

1976 • 1 citations