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Chemotherapy of Parasitic Worms: New Biochemical Strategies

Data up to Jan 2025

Published1979
Citations111
References79

Total Citations Per Year

Abstract

References (79)

N-formylmethionyl peptides as chemoattractants for leucocytes.

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Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

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THE QUANTITATIVE DISTRIBUTION OF 5‐HYDROXY‐TRYPTAMINE IN THE INVERTEBRATES, ESPECIALLY IN THEIR NERVOUS SYSTEMS*

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Über den jetzigen Stand der Chemotherapie

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The Effect of Serotonin (5-Hydroxytryptamine) on the Formation of Adenosine 3', 5'-Phosphate by Tissue Particles from the Liver Fluke, Fasciola hepatica

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1977 • 196 citations

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1974 • 162 citations

Aspects of the pharmacology of a new anthelmintic: pyrantel

1970 • 148 citations

Phosphofructokinase* *Some of the studies carried out by the author and reviewed here were supported by the U. S. Public Health Service Research Grant (AI04214) from the National Institute of Allergy and Infectious Diseases and a grant-in-aid from the American Heart Association.

1972 • 125 citations

Studies on the carbohydrate metabolism of the liver fluke Fasciola hepatica

1959 • 119 citations

THE POSSIBLE ROLE OF ACETYLCHOLINE IN SCHISTOSOMA MANSONI

1966 • 115 citations

Occurrence and Concentrations of Biogenic Amines in Trematodes

1972 • 93 citations

ACETYLCHOLINESTERASE ACTIVITY OF SCHISTOSOMA MANSONI*

1952 • 84 citations

THE RELATIONSHIP BETWEEN INHIBITION OF PHOSPHOFRUCTOKINASE ACTIVITY AND THE MODE OF ACTION OF TRIVALENT ORGANIC ANTIMONIALS ON SCHISTOSOMA MANSONI

1957 • 80 citations

Effect of serotonin on glycolysis in homogenates from the liver fluke Fasciola hepatica.

1962 • 76 citations

An in vitro method for the chemotherapeutic investigation of anthelminthic potency

1943 • 73 citations

Histochemical localization of esterase activity in schistosomes

1967 • 73 citations

Investigations on the Action of Piperazine on Ascaris Lumbricoides

1957 • 73 citations

Medicine and the Law

1959 • 71 citations

Metrifonate in urinary schistosomiasis.

1969 • 68 citations

Adenylate Cyclase from Brevibacterium liquefaciens

1974 • 67 citations

Uptake of 5-hydroxytryptamine by Schistosoma mansoni.

1973 • 63 citations

THE ACTIONS OF ANTIMONIALS ON GLYCOLYTIC ENZYMES OF SCHISTOSOMA MANSONI

1954 • 63 citations

Schistosome motility measurements: response to drugs.

1973 • 62 citations

Identification of chemicals of snail origin that attract Schistosoma mansoni miracidia

1974 • 60 citations

The effect of serotonin and related compounds on the carbohydrate metabolism of the liver fluke, Fasciola hepatica.

1959 • 58 citations

Inhibition by metrifonate and dichlorvos of cholinesterases in schistosomes

1972 • 54 citations

6-phosphofructokinase (pyrophosphate). Properties of the enzyme from Entamoeba histolytica and its reaction mechanism.

1976 • 53 citations

A CONTRIBUTION TO THE PHARMACOLOGY OF MOVEMENT IN THE LIVER FLUKE

1953 • 51 citations

THE EFFECT OF LYSERGIC ACID DIETHYLAMIDE, 5‐HYDROXYTRYPTAMINE, AND RELATED COMPOUNDS ON THE LIVER FLUKE, FASCIOLA HEPATICA

1957 • 51 citations

Schistosoma mansoni : Identification of Chemicals That Attract or Trap Its Snail Vector, Biomphalaria glabrata

1978 • 48 citations

The Pharmacology and Biochemistry of Parasitic Helminths

1964 • 47 citations

Effect of serotonin on phenol oxidase from the liver fluke Fasciola hepatica and from other sources

1958 • 46 citations

A CONTRIBUTION TO THE PHYSIOLOGY AND PHARMACOLOGY OF ASCARIS LUMBRICOIDES FROM THE PIG

1949 • 44 citations

Phosphofructokinase from the liver fluke Fasciola hepatica. i. Activation by adenosine 3',5'-phosphate and by serotonin.

1967 • 43 citations

Antischistosomal Action of Tubercidin administered after Absorption into Red Cells

1971 • 43 citations

Occurrence and Concentration of Biogenic Amines in Mesocestoides corti (Cestoda)

1974 • 42 citations

Biochemical effects of lysergic acid diethylamide on the liver fluke Fasciola hepatica

1970 • 40 citations

Identification of Chemicals triggering Cercarial Penetration Responses of Schistosoma mansoni

1969 • 40 citations

Measurement of chemotaxis in the slime mold Physarum polycephalum

1978 • 39 citations

Chemotaxis toward carbohydrates and amino acids in Physarum polycephalum

1978 • 39 citations

A Strategy for the Chemotherapy of Infectious Disease

1977 • 38 citations

A KYMOGRAPHIC STUDY OF THE ACTION OF DRUGS ON THE LIVER FLUKE (FASCIOLA HEPATICA)

1949 • 38 citations

Adenylate cyclase from Fasciola hepatica. 1. Ligand specificity of adenylate cyclase-coupled serotonin receptors.

1978 • 36 citations

Oxidative Phosphorylation in Adult Schistosoma mansoni

1972 • 36 citations

Adenosine 3′, 5′-cyclic monophosphate in

1973 • 35 citations

Adenosine 3′,5′-Monophosphate Phosphodiesterase in the Growth Medium of Physarum polycephalum

1971 • 33 citations

TREATMENT OF URINARY SCHISTOSOMIASIS WITH TRICHLOROPHONE

1967 • 31 citations

Sources of error in neurotransmitter analysis

1977 • 31 citations

Activity of Piperazine, in vitro, Against Ascaris lumbricoides

1955 • 30 citations

Testing arecoline hydrobromide as an anthelminthic for hydatid worms in dogs

1946 • 30 citations

An Adenosine 3',5'-Monophosphate-inhibited Protein Kinase from Physarum polycephalum

1971 • 30 citations

The Effects of Stibophen on Phosphofructokinases and Aldolases of Adult Filariids

1975 • 30 citations

Adenosine cyclic 3',5'-monophosphate in the liver fluke, Fasciola hepatica. I. Activation of adenylate cyclase by 5-hydroxytryptamine.

1976 • 29 citations

Adenylate cyclase from Fasciola hepatica. 2. Role of guanine nucleotides in coupling adenylate cyclase and serotonin receptors.

1978 • 26 citations

Effects of tubercidin and its ribonucleotides on various metabolic pathways in Schistosoma Mansoni

1972 • 24 citations

Effect of hormones on carbohydrate metabolism of invertebrates.

1967 • 23 citations

Effects of amino acids and light on the behavior of miracidia of Schistosomatium douthitti (Cort 1914)

1972 • 22 citations

The effect of metrifonate in vitro on Schistosoma haematobium and S. mansoni adults

1971 • 21 citations

Disulfiram—a compound that selectively induces abnormal egg production and lowers norepinephrine levels in Schistosoma mansoni

1978 • 21 citations

Phosphofructokinase from the liver fluke Fasciola hepatica. II. Kinetic properties of the enzyme.

1967 • 21 citations

Effect of methysergide and dihydroergotamine on Schistosoma mansoni.

1974 • 20 citations

Studies on the anthelmintic activity of hexylresorcinol and tetrachlorethylene

1944 • 19 citations

Adenosine cyclic 3',5'-monophosphate in the liver fluke, Fasciola hepatica. II. Activation of protein kinase by 5-hydroxytryptamine.

1976 • 19 citations

Phosphodiesterase in the liver fluke, fasciola hepatica

1977 • 19 citations

Effect of lysergic acid derivatives on the liver fluke Fasciola hepatica

1963 • 17 citations

Spectrofluorometric and chromatographic characterization of a butanol extract fromFasciola hepatica

1970 • 16 citations

Cyclic 3′,5′-AMP phosphodiesterase in Physarum polycephalum I. Chemotaxis toward inhibitors and cyclic nucleotides

1979 • 15 citations

Cyclic 3′,5′-AMP phosphodiesterase in Physarum polycephalum

1979 • 13 citations

The effects of thiouracil and thyroxine on the host-parasite relationship of Amplicaecum robertsi Sprent & Mines, 1960, in the mouse

1966 • 10 citations

Effect of some phosphodiesterase inhibitors on adenylate cyclase from the liver fluke, Fasciola hepatica

1979 • 10 citations

The effects of pregnancy and treatment with progesterone on the host–parasite relationship of Amplicaecum robertsi Sprent & Mines, 1960, in the mouse

1966 • 8 citations

An adenosine‐3′,5′‐monophosphate activated adenylate cyclase in the slime mold Physarum polycephalum

1978 • 7 citations

Actions of serotonin and epinephrine on intact and broken cell preparations from the liver fluke, Fasciola hepatica.

1959 • 6 citations

Phosphofructokinase activity in particulate-free extracts of Trypanosoma (trypanozoon) rhodesiense

1971 • 5 citations

Enhancement of the Antigenic Activity of Toxoids by Sympathomimetic Drugs

1955 • 1 citations

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