The Pathogenesis of Silicosis

AN EXAMINATION OF THE CYTOTOXIC EFFECTS OF SILICA ON MACROPHAGES

1966 • 868 citations

Fibronectin: current concepts of its structure and functions

1980 • 735 citations

Pathology of the lung

1985 • 702 citations

The Macrophage as an Effector Cell

1980 • 628 citations

Activity of a Macrophage Factor in Collagen Formation by Silica

1967 • 293 citations

Defense Mechanisms of the Respiratory Membrane1–4

2015 • 274 citations

Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role for interleukin 1 in the pathogenesis of silicosis.

1984 • 254 citations

Chrysotile asbestos inhalation in rats: deposition pattern and reaction of alveolar epithelium and pulmonary macrophages.

1981 • 234 citations

Leukotriene B4 production by the human alveolar macrophage: a potential mechanism for amplifying inflammation in the lung.

1984 • 188 citations

Cooperation between Mononuclear Phagocytes and Lymphocytes in Immunity

1980 • 149 citations

The Numerous Postulated Biological Manifestations of Interleukin-1

1984 • 136 citations

Immune complexes and autoantibodies in silicosis

1981 • 94 citations

Deposition and translocation of inhaled silica in rats. Quantification of particle distribution, macrophage participation, and function.

1982 • 91 citations

Kinetics of inflammatory and fibrotic pulmonary changes in a murine model of silicosis.

1985 • 76 citations

Experimental silicosis: morphologic and biochemical abnormalities produced by intratracheal instillation of quartz into guinea pig lungs.

1980 • 75 citations

The Regulation of Lung Fibroblast Proliferation by Alveolar Macrophages in Experimental Silicosis^1–3

1984 • 71 citations

Lung inflammation: role of endogenous chemotactic factors in attracting polymorphonuclear granulocytes.

1983 • 69 citations

The induction of fibrogenesis by silica-treated alveolar macrophages

1973 • 65 citations

Interstitial Pulmonary Fibrosis—Which Cell is the Culprit?^1,2

1983 • 59 citations

Current concepts about the pathogenesis of silicosis and asbestosis

1982 • 58 citations

The in-vitro effects of silica-treated hamster macrophages on collagen production by hamster fibroblasts

1973 • 57 citations

Mineral dust and cell recovery from the bronchoalveolar lavage of healthy Vermont granite workers.

1985 • 46 citations

Raised immunoglobulin concentrations in bronchoalveolar lavage fluid of healthy granite workers.

1986 • 44 citations

Lymphokine regulation of macrophage-derived growth factor secretion following pulmonary injury.

1985 • 43 citations

Effect of alveolar lining material-coated silica on rat alveolar macrophages.

1983 • 43 citations

Alveolar Macrophage Stimulation and Population Changes in Silica-Exposed Rats

1981 • 42 citations

Bronchoalveolar lavage in silicosis

1979 • 39 citations

Silica stimulation of chemotactic factor release by guinea pig alveolar macrophages.

1981 • 38 citations

The effects of silica dust and alveolar macrophages on lung fibroblasts grown

1974 • 34 citations

A study of macrophage-mediated initiation of fibrosis by asbestos and silica using a diffusion chamber technique.

1982 • 28 citations

Increased Prevalence of HLA-Aw19 and of the Phenogroup Aw19,B18 in Advanced Silicosis

1983 • 24 citations

What goes wrong with the macrophage in silicosis?

1982 • 17 citations

Use of backscattered electron imaging to quantify the distribution of inhaled crystalline silica.

1980 • 9 citations