Tissue-selective actions of estrogen analogs

Hormone Therapy To Prevent Disease and Prolong Life in Postmenopausal Women

1992 • 2,379 citations

Effects of Estrogen or Estrogen/ Progestin Regimens on Heart Disease Risk Factors in Postmenopausal Women

1995 • 2,281 citations

The ovariectomized rat model of postmenopausal bone loss

1991 • 1,345 citations

Effects of Tamoxifen on Bone Mineral Density in Postmenopausal Women with Breast Cancer

1992 • 1,139 citations

Association of Hormone-Replacement Therapy with Various Cardiovascular Risk Factors in Postmenopausal Women

1993 • 924 citations

Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.

1990 • 772 citations

Skeletal Effects of Estrogen*

1994 • 722 citations

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.

1994 • 649 citations

Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats.

1994 • 614 citations

Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. The Writing Group for the PEPI Trial

1995 • 602 citations

Cytokines and Estrogen in Bone: Anti-Osteoporotic Effects

1993 • 466 citations

Biochemical pharmacology of antiestrogen action.

1984 • 417 citations

Endocrine Pharmacology of Antiestrogens as Antitumor Agents*

1990 • 403 citations

Estrogen Treatment Prevents Osteopenia and Depresses Bone Turnover in Ovariectomized Rats*

1988 • 356 citations

Dynamics of Steroid Hormone Receptor Action

1980 • 348 citations

Effects of anti-estrogens on bone in castrated and intact female rats

1987 • 329 citations

Estrogenic action of DDT and its analogs

1969 • 320 citations

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions

1994 • 293 citations

Antagonism of estrogen action with a new benzothiophene derived antiestrogen

1983 • 244 citations

Tamoxifen prevents the skeletal effects of ovarian hormone deficiency in rats

1987 • 243 citations

Tamoxifen Inhibits Osteoclast-Mediated Resorption of Trabecular Bone in Ovarian Hormone-Deficient Rats*

1988 • 224 citations

Stromal-Epithelial Interactions in Sex Differentiation

1980 • 217 citations

Tamoxifen is a potent ‘pure’ anti-oestrogen in chick oviduct

1977 • 184 citations

Effect of tamoxifen on lumbar spine bone mineral density in postmenopausal women after 5 years

1994 • 169 citations

Raloxifene preserves bone strength and bone mass in ovariectomized rats.

1994 • 165 citations

Skeletal response of ovariectomized rats to low and high doses of 17β-estradiol

1991 • 156 citations

Estrogen Stimulation of Deoxyribonucleic Acid Synthesis in Uterine Epithelial Cells which Lack Estrogen Receptors*

1986 • 148 citations

3-[4-(1,2-Diphenylbut-1-enyl)phenyl]acrylic Acid: A Non-Steroidal Estrogen with Functional Selectivity for Bone over Uterus in Rats

1994 • 144 citations

Clomiphene protects against osteoporosis in the mature ovariectomized rat

1984 • 139 citations

DDT induces a Decrease in Eggshell Calcium

1969 • 136 citations

The effects of raloxifene on tibia histomorphometry in ovariectomized rats

1994 • 136 citations

Long-term adjuvant tamoxifen therapy for breast cancer

1990 • 117 citations

Effects of ovariectomy and estrogen on the serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3

1994 • 105 citations

Dual-energy X-ray absorptiometry of raloxifene effects on the lumbar vertebrae and femora of ovariectomized rats

1994 • 104 citations

Effects of Tamoxifen Treatment on Plasma Lipids and Lipoprotein Lipid Composition

1990 • 103 citations

The estrogen antagonist ICI 182,780 reduces cancellous bone volume in female rats.

1993 • 96 citations

A comparative study of the actions of tamoxifen, estrogen and progesterone in the ovariectomized rat

1991 • 95 citations

The effect of tamoxifen on bone mineral content in premenopausal women with breast cancer

1984 • 94 citations

Mechanism of action of estrogen on cancellous bone balance in tibiae of ovariectomized growing rats: Inhibition of indices of formation and resorption

1993 • 92 citations

Reduced chondroclast differentiation results in increased cancellous bone volume in estrogen-treated growing rats.

1994 • 77 citations

Effect of long-term tamoxifen therapy on cancellous bone remodeling and structure in women with breast cancer

1994 • 77 citations

Differential Sensitivity of Rat Uterine Growth and Epithelium Hypertrophy to Estrogens and Antiestrogens

1993 • 73 citations

Estrogen does not increase bone formation in growing rats.

1993 • 70 citations

Bone mineral content of women receiving tamoxifen for mastalgia

1989 • 68 citations

Effects of a non-steroidal pure antioestrogen, ZM 189,154, on oestrogen target organs of the rat including bones

1994 • 66 citations

Dose-Dependent Effects of Tamoxifen on Long Bones in Growing Rats: Influence of Ovarian Status*

1991 • 66 citations

The effects of tamoxifen on the osteopenia induced by sciatic neurotomy in the rat: A histomorphometric study

1988 • 57 citations

Raloxifene preserves bone strength and bone mass in ovariectomized rats

1994 • 52 citations

Antiestrogen and antiandrogen administration reduce bone mass in the rat

1989 • 51 citations

Stimulatory and Inhibitory Effects of Estrogen and Antiestrogen on Uterine Cell Division*

1981 • 44 citations

Therapeutic potential of pure antioestrogens in the treatment of breast cancer

1990 • 40 citations

Effects of estrogen and tamoxifen on serum osteocalcin levels in ovariectomized rats

1991 • 33 citations

The estrogenic and antiestrogenic properties of tamoxifen in GH4C1 pituitary tumor cells are gene specific.

1992 • 32 citations

Serum cholesterol reduction with tamoxifen

1990 • 31 citations

The estrogen antagonist ICI 182,780 reduces cancellous bone volume in female rats

1993 • 31 citations

TAMOXIFEN USE, OESTROGEN BINDING AND SERUM LIPIDS IN POSTMENOPAUSAL WOMEN WITH BREAST CANCER

1990 • 27 citations

Evidence that Estrogen Binding Sites are Present in Bone Cells and Mediate Medullary Bone Formation in Japanese Quail

1993 • 27 citations

Estrogen does not increase bone formation in growing rats

1993 • 24 citations

Risks and benefits of long-term treatment with estrogens.

1989 • 24 citations

Estrogen receptor mRNA is expressed in vivo in rat calvarial periosteum

1995 • 24 citations

Reduced chondroclast differentiation results in increased cancellous bone volume in estrogen-treated growing rats

1994 • 19 citations

Nuclear estrogen receptor in the reproductive tract of laying Japanese quail

1978 • 16 citations

The estrogenic and antiestrogenic properties of tamoxifen in GH4C1 pituitary tumor cells are gene specific

1992 • 15 citations

Amelioration of postmenopausal primary hyperparathyroidism during adjuvant tamoxifen for breast cancer

1989 • 12 citations

Tamoxifen and Norethisterone: Effects on Plasma Cholesterol and Total Body Calcium Content in the Estrogen-Deficient Rat

1994 • 11 citations

o,p′-DDT as an estrogen: An evaluation of its ability to compete with3H-estradiol for nuclear estrogen receptor sites in the quail oviduct

1978 • 10 citations

The effect of medroxyprogesterone acetate on bone metabolism in the oophorectomized, tamoxifen-treated rat.

1995 • 10 citations

The effect of medroxyprogesterone acetate on bone metabolism in the oophorectomized, tamoxifen-treated rat

1995 • 4 citations