Desensitization and noncompetitive blockade of GABAA receptors in ventral midbrain neurons by a neurosteroid dehydroepiandrosterone sulfate

Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons.

1981 • 559 citations

Neurosteroids: A new brain function?

1990 • 526 citations

Benzodiazepine impairs and β-carboline enhances performance in learning and memory tasks

1986 • 500 citations

Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons

1989 • 436 citations

The neurosteroid dehydroepiandrosterone sulfate is an allosteric antagonist of the GABAA receptor

1990 • 433 citations

Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.

1991 • 426 citations

Benzodiazepines, memory and mood: a review

1991 • 402 citations

Estimating kinetic constants from single channel data

1983 • 307 citations

Intracellular calcium ions decrease the affinity of the GABA receptor

1986 • 255 citations

'Concentration‐clamp' study of gamma‐aminobutyric‐acid‐induced chloride current kinetics in frog sensory neurones.

1986 • 218 citations

Receptor binding and electrophysiological effects of Dehydroepiandrosterone sulfate, an antagonist of the GABAA receptor

1991 • 216 citations

gamma-Aminobutyric acid receptor channels in adrenal chromaffin cells: a patch-clamp study.

1985 • 206 citations

gamma-Aminobutyric acid A or C receptor? gamma-Aminobutyric acid rho 1 receptor RNA induces bicuculline-, barbiturate-, and benzodiazepine-insensitive gamma-aminobutyric acid responses in Xenopus oocytes.

1992 • 201 citations

Effects of dehydroepiandrosterone and its sulfate on brain tissue in culture and on memory in mice

1987 • 199 citations

Whole-cell voltage-clamp study of the fading of GABA-activated currents in acutely dissociated hippocampal neurons

1986 • 178 citations

Burst kinetics of single calcium‐activated potassium channels in cultured rat muscle.

1983 • 174 citations

Rat hippocampal neurons in culture: voltage-clamp analysis of inhibitory synaptic connections

1984 • 165 citations

Inhibitory post‐synaptic currents in rat hippocampal CA1 neurones.

1984 • 155 citations

A steroid anesthetic prolongs inhibitory postsynaptic currents in cultured rat hippocampal neurons

1987 • 144 citations

Gamma‐aminobutyric acid uptake and the termination of inhibitory synaptic potentials in the rat hippocampal slice.

1985 • 139 citations

Spontaneous inhibitory post-synaptic potentials in hippocampus: Mechanism for tonic inhibition

1980 • 134 citations

Synaptic Transmission in Hippocampal Neurons: Numerical Reconstruction of Quantal IPSCs

1990 • 109 citations

Noncompetitive inhibition of gamma-aminobutyric acidA channels by Zn.

1991 • 104 citations

Voltage-clamp study on GABA response desensitization in single pyramidal cells dissociated from the hippocampus of adult guinea pigs

1984 • 103 citations

Treatment strategies for senile dementia: antagonist β-carbolines

1988 • 103 citations

Desensitization of .gamma.-aminobutyric acid receptor from rat brain: two distinguishable receptors on the same membrane

1987 • 93 citations

Actions of benzodiazepine and beta-carboline derivatives on gamma-aminobutyric acid-activated Cl- channels recorded from membrane patches of neonatal rat cortical neurons in culture.

1987 • 87 citations

Actions of pentobarbital on rat brain receptors expressed in Xenopus oocytes

1986 • 85 citations

Contribution of chloride shifts to the fade of gamma‐aminobutyric acid‐gated currents in frog dorsal root ganglion cells.

1987 • 76 citations

cAMP increases the rate of GABA_A receptor desensitization in chick cortical neurons

1989 • 70 citations

The Biologic Role of Dehydroepiandrosterone (DHEA)

1990 • 64 citations

GABA and glycine actions on spinal motoneurons

1977 • 62 citations

Desensitization of GABA-activated currents and channels in cultured cortical neurons

1992 • 58 citations

The biologic role of dehydroepiandrosterone (DHEA)

1992 • 55 citations

Desensitization of GABA-induced currents in cultured rat hippocampal neurons

1992 • 53 citations

‘Inverse agonists’, cooperativity and drug action at benzodiazepine receptors

1986 • 52 citations

Modulation of neurotransmitter receptor desensitization: chlordiazepoxide stimulates fading of the GABA response

1988 • 47 citations

Does glial uptake affect GABA responses? An intracellular study on rat dorsal root ganglion neurones in vitro

1980 • 39 citations

Effects of anisatin on the GABA action in the crayfish neuromuscular junction

1981 • 25 citations

GABA ‘desensitization’ of frog primary afferent fibers

1982 • 23 citations

Involvement of GABAergic systems in benzodiazepine-induced impairment of passive avoidance learning in mice

1991 • 22 citations

DEHYDROEPIANDROSTERONE (DHEA) AND ITS SULFATE (DHEAS) AS NEURAL FACILITATORS: EFFECTS ON BRAIN TISSUE IN CULTURE AND ON MEMORY IN YOUNG AND OLD MICE. A CYCLIC GMP HYPOTHESIS OF ACTION OF DHEA AND DHEAS IN NERVOUS SYSTEM AND OTHER TISSUES

1990 • 20 citations

The effects of amoxapine on electroencephalographic stages of sleep in normal human subjects

1975 • 16 citations

COGNITIVE EFFECTS OF DHEA REPLACEMENT THERAPY

1990 • 13 citations

THE BIOLOGICAL SIGNIFICANCE OF DEHYDROEPIANDROSTERONE

1990 • 8 citations

Cited By (0)

Loading...