Effects of OPC-18790, a New Positive Inotropic Agent, on Canine Ventricular Arrhythmias

The Heart and Cardiovascular System

1992 • 655 citations

Action potentials, afterpotentials, and arrhythmias.

1977 • 474 citations

Canine-effective plasma concentrations of antiarrhythmic drugs on the two-stage coronary ligation arrhythmia.

1982 • 71 citations

Novel positive inotropic agents: synthesis and biological activities of 6-(3-amino-2-hydroxypropoxy)-2(1H)-quinolinone derivatives

1992 • 65 citations

Effects of antiarrhythmic drugs on canine ventricular arrhythmia models: Which electrophysiological characteristics of drugs are related to their effectiveness?

1991 • 61 citations

Canine digitalis arrhythmia as a model for detecting Na-channel blocking antiarrhythmic drugs: A comparative study using other canine arrhythmia models and the new antiarrhythmic drugs, propafenone, tocainide, and SUN 1165

1985 • 57 citations

Mode and mechanism of action of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, on the dog heart.

1984 • 56 citations

Effective Plasma Concentrations of Antiarrhythmic Drugs Against Sustained Halothane-Adrenaline Arrhythmia in Dogs

1983 • 50 citations

In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, in various animals.

1984 • 43 citations

Cardiovascular actions of OPC-18790: A novel positive inotropic agent with little chronotropic action

1992 • 32 citations

The first demonstration of CGRP-immunoreactive fibers in canine hearts: Coronary vasodilator, inotropic and chronotropic effects of CGRP in canine isolated, blood-perfused heart preparations.

1989 • 29 citations

Comparison of Cardiovascular Effects of Pirmenol with Those of Disopyramide in Isolated Canine Heart Preparations Cross-Circulated with a Donor Dog

1990 • 24 citations

Effects of OPC‐8212, a new positive inotropic agent, on canine ventricular arrhythmias

1986 • 17 citations

Positive inotropic effect of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212) in the dog with experimentally-induced right-sided heart failure.

1984 • 12 citations