Consequences of Complexity within Biological Networks: Robustness and Health, or Vulnerability and Disease

Error and attack tolerance of complex networks

2000 • 6,651 citations

The large-scale organization of metabolic networks

2000 • 4,250 citations

From molecular to modular cell biology

1999 • 3,617 citations

Robustness in simple biochemical networks

1997 • 1,531 citations

The control of flux.

1973 • 1,381 citations

Protein function in the post-genomic era

2000 • 721 citations

Monogenic traits are not simple: lessons from phenylketonuria

1999 • 428 citations

Phenotypes of Patients with “Simple” Mendelian Disorders Are Complex Traits: Thresholds, Modifiers, and Systems Dynamics

2000 • 418 citations

Modifier Genes Convert “Simple” Mendelian Disorders to Complex Traits

2000 • 252 citations

Robustness Analysis of the Escherichia coli Metabolic Network

2000 • 211 citations

Synergistic Heterozygosity: Disease Resulting from Multiple Partial Defects in One or More Metabolic Pathways

2000 • 204 citations

Regulation Analysis Of Energy Metabolism

1997 • 129 citations

How robust is the Internet?

2000 • 70 citations

Regulation and Control in Complex, Dynamic Metabolic Systems: Experimental Application of the Top-Down Approaches of Metabolic Control Analysis to Fatty Acid Oxidation and Ketogenesis

1996 • 16 citations