Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo

Beyond Cholesterol

1989 • 6,533 citations

Compensatory Enlargement of Human Atherosclerotic Coronary Arteries

1987 • 3,549 citations

Molecular Bases of the Acute Coronary Syndromes

1995 • 2,049 citations

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology.

1994 • 1,913 citations

Thrombosis and Acute Coronary-Artery Lesions in Sudden Cardiac Ischemic Death

1984 • 1,700 citations

Low density lipoprotein undergoes oxidative modification in vivo.

1989 • 1,537 citations

Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?

1988 • 1,483 citations

Does Visual Interpretation of the Coronary Arteriogram Predict the Physiologic Importance of a Coronary Stenosis?

1984 • 1,233 citations

Effect of lovastatin on early carotid atherosclerosis and cardiovascular events. Asymptomatic Carotid Artery Progression Study (ACAPS) Research Group.

1994 • 887 citations

Malondialdehyde-Altered Protein Occurs in Atheroma of Watanabe Heritable Hyperlipidemic Rabbits

1988 • 757 citations

Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture.

1995 • 723 citations

Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

1990 • 627 citations

Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products.

1987 • 625 citations

Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.

1995 • 596 citations

Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma.

1996 • 557 citations

Atherosclerotic plaque caps are locally weakened when macrophages density is increased

1991 • 541 citations

Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice

1995 • 518 citations

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

1994 • 498 citations

Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits.

1990 • 478 citations

Plaque fissures in human coronary thrombosis

1966 • 424 citations

Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein.

1996 • 354 citations

Pre-existing coronary stenoses in patients with first myocardial infarction are not necessarily severe

1988 • 291 citations

Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit.

1989 • 250 citations

Increased Autoantibody Titers Against Epitopes of Oxidized LDL in LDL Receptor–Deficient Mice With Increased Atherosclerosis

1995 • 247 citations

Role of oxidised low density lipoprotein in atherogenesis

1993 • 230 citations

Addition of sulfhydryl groups of Escherichia coli ribosomes by protein modification with 2-iminothiolane (methyl 4-mercaptobutyrimidate)

1978 • 201 citations

Fatty streak expansion and maturation in Watanabe Heritable Hyperlipemic and comparably hypercholesterolemic fat-fed rabbits.

1987 • 174 citations

Distribution of plasma proteins across the human aortic wall Barrier functions of endothelium and internal elastic lamina

1980 • 168 citations

Impact of compensatory enlargement of atherosclerotic coronary arteries on angiographic assessment of coronary artery disease.

1989 • 167 citations

Immunostaining of human autopsy aortas with antibodies to modified apolipoprotein B and apoprotein(a).

1993 • 150 citations

Immunological Evidence for the Presence of Advanced Glycosylation End Products in Atherosclerotic Lesions of Euglycemic Rabbits

1995 • 135 citations

Imaging human atherosclerosis with 99mTc-labeled low density lipoproteins.

1988 • 134 citations

Monoclonal antibody pretargetting techniques for tumour localization

1991 • 112 citations

Renal and Systemic Transvascular Albumin Leakage in Severe Atherosclerosis

1995 • 102 citations

External imaging of human atherosclerosis.

1983 • 95 citations

Noninvasive Localization of Experimental Atherosclerotic Lesions With Mouse/Human Chimeric Z2D3 F(ab′) ₂ Specific for the Proliferating Smooth Muscle Cells of Human Atheroma

1995 • 89 citations

Assessment of stenoses in coronary angioplasty. Inter- and intraobserver variability

1983 • 86 citations

Chemical evaluation of conformational differences in native and chemically modified proteins

1966 • 84 citations

Scintigraphic detection of carotid atherosclerosis with indium-111-labeled autologous platelets.

1980 • 77 citations

Generation, Characterization, and Histochemical Application of Monoclonal Antibodies Selectively Recognizing Oxidatively Modified ApoB-Containing Serum Lipoproteins

1995 • 77 citations

Dissociation of [3H]cholesterol and 125I-labelled plasma protein influx in normal and atheromatous rabbit aorta

1968 • 67 citations

Effect of vitamin E on atherogenesis in LDL receptor-deficient rabbits

1995 • 62 citations

Rapid blood clearance of biotinylated IgG after infusion of avidin.

1989 • 61 citations

Indium-111-labeled LDL: a potential agent for imaging atherosclerotic disease and lipoprotein biodistribution.

1990 • 57 citations

Evidence for more extensive deposits of epitopes of oxidized low density lipoprotein in aortas of young people with elevated serum thiocyanate levels

1996 • 53 citations

Magnetic resonance imaging to study lesions of atherosclerosis in the hyperlipidemic rabbit aorta

1996 • 52 citations

Radionuclide imaging of experimental atherosclerosis with nonspecific polyclonal immunoglobulin G.

1989 • 49 citations

Coronary Artery Screening by Electron Beam Computed Tomography

1995 • 44 citations

In vivo technetium-99m S12 antibody imaging of platelet alpha-granules in rabbit endothelial neointimal proliferation after angioplasty.

1991 • 42 citations

External Imaging of Atherosclerosis in Rabbits Using an ¹²³I‐Labeled Synthetic Peptide Fragment

1993 • 40 citations

Functional and Anatomic Evaluation of Carotid Atherothrombosis

1995 • 39 citations

Indium-111-labeled platelet scintigraphy in carotid atherosclerosis.

1989 • 34 citations

Early Change of Vascular Permeability in Hypercholesterolemic Rabbits

1995 • 25 citations

Evaluation of indium-111-polyclonal immunoglobulin G to quantitate atherosclerosis in Watanabe heritable hyperlipidemic rabbits with scintigraphy: effect of age and treatment with antioxidants or ethinylestradiol.

1993 • 22 citations

Biodistribution and radioimmunopharmacokinetics of 131I-Ama monoclonal antibody in atherosclerotic rabbits

1995 • 20 citations

Detection of experimental atherosclerosis with indium-111 radiolabelled hematoporphyrin derivative

1989 • 16 citations

Permeability of arterial endothelium to plasma macromolecules

1977 • 14 citations

Deleted Work

1955 • 0 citations