Epinephrine-stimulated phosphorylation of pyruvate kinase in hepatocytes

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

1969 • 4,428 citations

Polyacrylamide Gel Electrophoresis of Viral Proteins

1971 • 1,477 citations

Cyclic GMP Metabolism and Involvement in Biological Regulation

1977 • 629 citations

X-ray intensifying screens greatly enhance the detection by autoradiography of the radioactive isotopes 32P and 125I

1978 • 419 citations

Combinations of specific color reactions useful in the peptide mapping technique

1965 • 398 citations

Studies on the alpha-adrenergic activation of hepatic glucose output. I. Studies on the alpha-adrenergic activation of phosphorylase and gluconeogenesis and inactivation of glycogen synthase in isolated rat liver parenchymal cells.

1976 • 350 citations

Studies on the Role of Adenosine 3',5'-Monophosphate in the Hepatic Actions of Glucagon and Catecholamines

1971 • 321 citations

Studies on alpha-adrenergic activation of hepatic glucose output. Studies on role of calcium in alpha-adrenergic activation of phosphorylase.

1977 • 289 citations

Studies on alpha-adrenergic activation of hepatic glucose output. Relationship between alpha-adrenergic stimulation of calcium efflux and activation of phosphorylase in isolated rat liver parenchymal cells.

1978 • 259 citations

“Fluorokinase” and pyruvic kinase

1958 • 224 citations

Cyclic AMP and Aclrenergic Receptor Control of Rat Liver Glycogen Metabolism

1972 • 214 citations

Gluconeogenesis in the perfused liver

1966 • 200 citations

The role of calcium ion as a mediator of the effects of angiotensin II, catecholamines, and vasopressin on the phosphorylation and activity of enzymes in isolated hepatocytes.

1979 • 176 citations

Lack of Correlation between Catecholamine Effects on Cyclic Adenosine 3′:5′-Monophosphate and Gluconeogenesis in Isolated Rat Liver Cells

1973 • 173 citations

Phosphorylation of purified rat liver pyruvate kinase by cyclic 3′,5′-AMP-stimulated protein kinase

1974 • 172 citations

Hepatic pyruvate kinase. Regulation by glucagon, cyclic adenosine 3'-5'-monophosphate, and insulin in the perfused rat liver.

1976 • 168 citations

Rapid Reciprocal Changes in Rat Hepatic Glycolytic Enzyme and Fructose Diphosphatase Activities following Insulin and Glucagon Injection

1974 • 135 citations

A rapid method for the isolation of large quantities of rat liver parenchymal cells with high anabolic rates

1972 • 132 citations

Studies on alpha-adrenergic activation of hepatic glucose output.

1978 • 121 citations

Stimulation of glucagon of in vivo phosphorylation of rat hepatic pyruvate kinase.

1978 • 119 citations

Studies on the role of cyclic guanosine 3':5'-monophosphate and extracellular Ca2+ in the regulation of glycogenolysis in rat liver cells.

1976 • 119 citations

Hormonal control of [14C]glucose synthesis from [U-14C]dihydroxyacetone and glycerol in isolated rat hepatocytes

1976 • 108 citations

Studies on the Regulation of Gluconeogenesis in Isolated Rat Liver Cells by Epinephrine and Glucagon

1974 • 107 citations

Regulation in vitro of rat liver pyruvate kinase by phosphorylation-dephosphorylation reactions, catalyzed by cyclic-AMP dependent protein kinases and a histone phosphatase

1976 • 106 citations

Amino acid sequence of a (32P)phosphopeptide from pig liver pyruvate kinase phosphorylated by cyclic 3′,5′-AMP-stimulated protein kinase and γ-(32P)ATP

1974 • 102 citations

The effects of glucagon, catecholamines, and the calcium ionophore A23187 on the phosphorylation of rat hepatocyte cytosolic proteins.

1978 • 101 citations

Comparative kinetic studies on the L-type pyruvate kinase from rat liver and the enzyme phosphorylated by cyclic 3′,5′-AMP-stimulated protein kinase

1976 • 96 citations

Role of pyruvate kinase in the regulation of gluconeogenesis from L-lactate.

1977 • 94 citations

Studies on the phosphorylation and dephosphorylation of L-type pyruvate kinase by the catalytic subunit of cyclic AMP-dependent protein kinase.

1980 • 92 citations

Control of pyruvate kinase activity by glucagon in isolated hepatocytes

1976 • 75 citations

Glucagon-stimulated phosphorylation of pyruvate kinase in hepatocytes.

1978 • 75 citations

Rapid reciprocal changes of rat hepatic glycolytic enzymes and fructose-1,6-diphosphatase following glucagon and insulin injection in vivo

1972 • 74 citations

Relationship of Some Hepatic Actions of Insulin to the Intracellular Level of Cyclic Adenylate

1972 • 63 citations

Effects of Guanosine 3',5'-Monophosphate on the Perfused Rat Liver

1971 • 62 citations

Acute hormonal control of pyruvate kinase and lactate formation in the isolated rat hepatocyte

1978 • 57 citations

Studies on the cyclic 3':5'-AMP-stimulated pig liver protein kinase reaction with pyruvate kinase as substrate.

1977 • 57 citations

Amino acid sequence at the phosphorylated site of rat liver pyruvate kinase

1975 • 50 citations

Adrenergic control of the cyclic AMP-dependent protein kinase and pyruvate kinase in isolated hepatocytes. Application of a synthetic peptide substrate for measuring protein kinase activity.

1978 • 48 citations

Cyclic nucleotide-, pyruvate- and hormone-induced changes in pyruvate kinase activity in isolated rat hepatocytes

1976 • 47 citations

Cyclic nucleotides and gluconeogenesis by rat liver cells

1975 • 39 citations

Rapid Reciprocal Changes in Rat Tissue Enzyme Activities following Epinephrine Injection

1974 • 38 citations

Evidence for a proteolytic modification of liver pyruvate kinase in fasted rats

1979 • 34 citations

The Rapid Changes of Hepatic Glycolytic Enzymes and Fructose-1, 6-Diphosphatase Activities after Intravenous Glucagon in Humans

1974 • 32 citations

Effect of hormones on content of purine nucleoside cyclic monophosphates in perfused rat liver

1978 • 25 citations

The subunit structure of rat liver pyruvate kinase

1978 • 15 citations

Cyclic AMP stimulated phosphorylation of liver pyruvate kinase in hepatocytes

1978 • 14 citations

Adrenergic receptors

1977 • 7 citations