Localisation of the monocyte-binding region on human immunoglobulin G

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.

1981 • 1,432 citations

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-.ANG. resolution

1981 • 1,286 citations

Human neutrophil Fc gamma receptor distribution and structure.

1982 • 577 citations

Methods for Studying Mononuclear Phagocytes

1981 • 576 citations

Red Cells Coated with Immunoglobulin G: Binding and Sphering by Mononuclear Cells in Man

1967 • 475 citations

Immunoglobulin G: Functional sites

1985 • 442 citations

Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages.

1975 • 314 citations

Structural Aspects and Heterogeneity of Immunoglobulin Fc Receptors

1981 • 270 citations

Receptors for IgG: subclass specificity of receptors on different mouse cell types and the definition of two distinct receptors on a macrophage cell line.

1977 • 199 citations

Effector functions of a monoclonal aglycosylated mouse IgG2a: Binding and activation of complement component C1 and interaction with human monocyte Fc receptor

1985 • 195 citations

The C1q receptor site on immunoglobulin G

1980 • 161 citations

Ultracentrifuge studies of the binding of IgG of different subclasses to the Clq subunit of the first component of complement

1976 • 159 citations

The structure and function of immunoglobulin domains. II. The importance of interchain disulfide bonds and the possible role of molecular flexibility in the interaction between immunoglobulin G and complement.

1975 • 154 citations

Monoclonal antibodies (McAbs) to determinants on human gamma chains: properties of antibodies showing subclass restriction or subclass specificity.

1982 • 153 citations

The Binding of Human Immunoglobulin G1 Monomer and Small, Covalently Cross-Linked Polymers of Immunoglobulin G1 to Human Peripheral Blood Monocytes and Polymorphonuclear Leukocytes

1982 • 152 citations

Characterization of the Fc receptor for IgG on a human macrophage cell line, U937.

1980 • 137 citations

Classes and subclasses of rat immunoglobulins: Interaction with the complement system and with staphylococcal protein A

1978 • 135 citations

Separate Fc-receptors for immunoglogulins IgG2a and IgG2b on an established cell line of mouse macrophages.

1976 • 115 citations

Segmental flexibility of immunoglobulin G antibody molecules in solution: a new interpretation

1981 • 114 citations

RECONSTITUTION OF 7S MOLECULES FROM L AND H POLYPEPTIDE CHAINS OF ANTIBODIES AND γ-GLOBULINS

1964 • 102 citations

Quantitative influence of antibody and complement coating of red cells on monocyte-mediated cell lysis.

1978 • 88 citations

The Structure and Function of Immunoglobulin Domains

1975 • 87 citations

Specificity of fc receptors for IgG2a, IgG1/IgG2b, and IgE on rat macrophages.

1981 • 86 citations

Changes in quaternary structure of IgG upon reduction of the interheavy-chain disulfide bond.

1979 • 83 citations

Separate Fc-Receptors for Immunoglobulins IgG2a and IgG2b on an Established Cell Line of Mouse Macrophages

1976 • 83 citations

The binding of human and guinea-pig IgG subclasses to homologous macrophage and monocyte Fc receptors.

1978 • 80 citations

Relationship between the Papain Sensitivity of Human γG Immunoglobulins and their Heavy Chain Subclass

1968 • 77 citations

The Subclass Specificity for the Binding of Murine Myeloma Proteins to Macrophage and Lymphocyte Cell Lines and to Normal Spleen Cells

1978 • 71 citations

Functional affinity constants of the reaction between 125I-labelled C1q and C1q binders and their use in the measurement of plasma C1q concentrations.

1977 • 71 citations

Properties of monoclonal antibodies to human immunoglobulin kappa and lambda chains.

1981 • 67 citations

The role of the inter-heavy chain disulfide bond in modulating the flexibility of immunoglobulin G antibody

1977 • 60 citations

Conformational changes induced in a homogeneous antitype III pneumococcal antibody by oligosaccharides of increasing size

1975 • 60 citations

Antibody‐Induced Hemolytic Activity of Human Blood Monocytes

1974 • 58 citations

Conformational changes accompanying the dissociation and association of immunoglobulin-G subunits

1972 • 56 citations

Monocyte receptors for the Fc portion of IgG studies with monomeric human IgG1: normal in vitro expression of Fc gamma receptors in HLA-B8/Drw3 subjects with defective Fc gamma-mediated in vivo clearance.

1982 • 50 citations

Rotational dynamics of monoclonal anti-dansyl immunoglobulins

1982 • 50 citations

Human monocytes, B lymphocytes, and non-B lymphocytes each have structurally unique Fc gamma receptors.

1983 • 49 citations

The monocyte binding domain(S) on human immunoglobulin G

1984 • 44 citations

The Mechanism of Activation of the First Component of Complement by a Univalent Hapten-IgG Antibody Complex

1977 • 40 citations

The use of anti-IgG monoclonal antibodies in mapping the monocyte receptor site on IgG

1986 • 37 citations

Conformational change and complementarity in the combination of H and L chains of immunoglobulin-G.

1967 • 36 citations

Human placentae membrane receptor for IgG—i. Studies on properties and solubilization of the receptor

1981 • 34 citations

Comparison of the cytophilic activities of guinea pig IgG₁ and IgG₂ antibodies

1976 • 34 citations

Fc receptors of a human promyelocytic leukemic cell line: evidence for two types of receptors defined by binding of the staphylococcal protein A-IgG1 complex.

1980 • 34 citations

Binding of mouse monoclonal antibodies to human leukaemic cells via the Fc receptor: a possible source of 'false positive' reactions in specificity screening.

1983 • 34 citations

Binding sites for Fcγ receptors on immunoglobulin G and factors influencing their expression

1982 • 33 citations

Fractionation of rat IgG subclasses and screening for IgG Fc-binding to bacteria

1982 • 31 citations

Characterization of ligand-binding activity of isolated murine Fc gamma receptor.

1981 • 28 citations

Human monocyte binding of homologous monomer and complexed IgG.

1982 • 27 citations

Structural requirements of immunoglobulin G for binding to the Fc gamma receptors of the human tumor cell lines U937, HL-60, ML-1, and K562.

1985 • 23 citations

Characterization of a polyvalent antibody directed against the IgG Fc receptor of human mononuclear phagocytes.

1985 • 22 citations

Evidence for two distinct Fc receptors on guinea pig peritoneal macrophages

1981 • 20 citations

Effects of immunoglobulin structure on Fc receptor binding: a mouse myeloma variant immunoglobulin with a gamma 2b-gamma 2a hybrid heavy chain having a complete gamma 2a Fc region fails to bind to gamma 2a Fc receptors on mouse macrophages.

1982 • 20 citations

Soluble immune complexes binding to human monocytes and polymorphonuclear leucocytes.

1981 • 19 citations

The localization of the binding site(s) on human IgG1 for the Fc receptors on homologous monocytes and heterologous mouse macrophages.

1983 • 15 citations

Preparation and Characterization of Rabbit IgG Fractions

1975 • 15 citations

The binding of rabbit IgG and its enzymatically derived fragments to homologous peritoneal macrophages.

1979 • 14 citations

Studies on the asymmetrically attached oligosaccharide of rabbit immunoglobulin-G. II. On the biological function of the C2-oligosaccharide.

1970 • 11 citations

The effect of fragment b of staphylococcal protein a on the binding of rabbit IgG to human granulocytes and monocytes

1982 • 11 citations

Design, construction and properties of novel protein molecules

1985 • 11 citations

A requirement for native (undenatured) IgG for detection of species specificity of the IgG-Fc receptor on lymphocytes

1981 • 9 citations

OBTAINING AND CULTURING HUMAN MONOCYTES

1981 • 9 citations

The use of protein A and concanavalin A to examine the possible role of the carbohydrate of IgG in the binding of Clq

1981 • 7 citations

Isolation of a rabbit IgG fraction with cytophilic properties

1983 • 6 citations

Binding, fractionation, and papain susceptibility of groups d and e rabbit IgG allotypes.

1980 • 4 citations