Effect of chelating agents and metal ions on the degradation of DNA by bleomycin

The catalytic decomposition of hydrogen peroxide by iron salts

1934 • 2,483 citations

Base Specificity in the Interaction of Polynucleotides with Antibiotic Drugs

1965 • 480 citations

ON THE MECHANISM OF ACTION OF BLEOMYCIN : SCISSION OF DNA STRANDS IN VITRO AND IN VIVO

1969 • 328 citations

A role for ferrous ion and oxygen in the degradation of DNA by bleomycin

1976 • 291 citations

Nucleic Acids and Metals

1959 • 270 citations

Evidence for the involvement of iron in the ADP-activatedperoxidation of lipids in microsomes and mitochondria

1964 • 267 citations

The mechanism of the bleomycin-induced cleavage of DNA

1977 • 247 citations

Bleomycin-DNA interactions: fluorescence and proton magnetic resonance studies

1977 • 238 citations

Chemical analysis of DNA alterations

1968 • 222 citations

Evidence for superoxide-dependent reduction of Fe3+ and its role in enzyme-generated hydroxyl radical formation

1976 • 201 citations

Action of Bleomycin on DNA and RNA

1972 • 195 citations

Escherichia coli Deoxyribonucleic Acid Polymerase I, a Zinc Metalloenzyme

1973 • 190 citations

The mechanism of the degradation of DNA by streptonigrin

1976 • 187 citations

Increased DNA chain breakage by combined action of bleomycin and superoxide radical

1975 • 183 citations

ON THE MECHANISM OF ACTION OF BLEOMYCIN

1970 • 139 citations

The combined effects of bleomycin and sulfhydryl compounds on the thermal denaturation of DNA

1969 • 126 citations

Release of free bases from deoxyribonucleic acid after reaction with bleomycin.

1972 • 123 citations

Characterization of chain breakage in DNA induced by bleomycin

1974 • 102 citations

Polynucleotide Ligase Activity in Cells Infected with Simian Virus 40, Polyoma Virus, or Vaccinia Virus

1969 • 93 citations

Characterization of DNA strand breakage in vitro by the antitumor protein neocarzinostatin

1977 • 88 citations

Intermediates in the Synthesis of Type 2 Adenovirus Deoxyribonucleic Acid

1971 • 74 citations

Single-strand scissions induced in circular and linear λ DNA by the presence of dithiothreitol and other reducing agents

1967 • 74 citations

Effects of Reducing and Oxidizing Agents on the Action of Bleomycin1

1975 • 71 citations

REACTION OF BLEOMYCIN WITH DNA

1971 • 66 citations

THE EFFECT OF BLEOMYCIN ON SV40 DNA: CHARACTERISTICS OF BLEOMYCIN ACTION WHICH PRODUCES A SINGLE SCISSION IN A SUPERHELICAL FORM OF SV40 DNA

1973 • 65 citations

Mechanism of oxygenation of ferrous ion in neutral solution

1970 • 63 citations

Proton nuclear magnetic resonance study of bleomycin in aqueous solution. Assignment of resonances

1977 • 49 citations

Bleomycin, an inhibitor of vaccinia virus replication

1974 • 47 citations

Effect of ATP and other nucleotides on the bleomycin-induced degradation of vaccinia virus DNA

1976 • 42 citations

Interactions between bleomycins and metals.

1976 • 20 citations

Bleomycin-induced breakage of closed-circular DNA

1977 • 14 citations

MECHANISM OF THE ANTIVIRAL ACTION OF BLEOMYCIN

1977 • 11 citations