Formation of C5a during cardiopulmonary bypass: Inhibition by precoating with heparin

Complement Activation during Cardiopulmonary Bypass

1981 • 1,163 citations

Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes.

1978 • 512 citations

A New Non-Thrombogenic Surface Prepared by Selective Covalent Binding of Heparin Via a Modified Reducing Terminal Residue

1983 • 437 citations

Reduced complement activation with heparin-coated oxygenator and tubings in coronary bypass operations

1992 • 255 citations

Biochemistry and Biology of Anaphylatoxins

1986 • 169 citations

Modulation of the formation of the amplification convertase of complement, C3b, Bb, by native and commercial heparin.

1978 • 165 citations

Effect of time, temperature and anticoagulants on in vitro complement activation: consequences for collection and preservation of samples to be examined for complement activation.

1988 • 165 citations

Structural Determinants of the Capacity of Heparin to Inhibit the Formation of the Human Amplification C3 Convertase

1981 • 156 citations

Deposition of Terminal C5b–9 Complement Complexes on Erythrocytes and Leukocytes during Cardiopulmonary Bypass

1988 • 155 citations

Radioimmunoassay for anaphylatoxins: A sensitive method for determining complement activation products in biological fluids

1984 • 142 citations

Biocompatibility of extracorporeal circulation

1991 • 129 citations

Fluid phase generation of terminal complement complex as a novel index of bioincompatibility

1990 • 124 citations

Complement activation during major operations with or without cardiopulmonary bypass

1987 • 117 citations

Accentuated Formation of the Terminal C5b-9 Complement Complex in Patient Plasma Precedes Development of the Adult Respiratory Distress Syndrome

1988 • 95 citations

Complement activation and clearance in acute illness and injury: evidence for C5a as a cell-directed mediator of the adult respiratory distress syndrome in man.

1985 • 86 citations

Potentiation of C1-esterase inhibitor activity by heparin

1976 • 86 citations

In vivo clearance and tissue distribution of C5a and C5a des arginine complement fragments in rabbits.

1982 • 72 citations

Complement Activation in Cardiopulmonary Bypass, with Special Reference to Anaphylatoxin Production in Membrane and Bubble Oxygenators

1988 • 64 citations

Detection of native human complement components C3 and C5 and their primary activation peptides C3a and C5a (anaphylatoxic peptides) by ELISAs with monoclonal antibodies

1988 • 60 citations

Relative inefficiency of terminal complement activation.

1988 • 60 citations

Sensitive ELISA for quantitating the terminal membrane C5b-9 and fluid-phase SC5b-9 complex of human complement

1987 • 56 citations

Complement activation produced by biomaterials.

1986 • 50 citations

A Sensitive Enzyme Immunoassay for the Quantitation of Human C5a/C5a(desArg) Anaphylatoxin Using a Monoclonal Antibody with Specificity for a Neoepitope

1991 • 45 citations

Generation of an activated form of human C5 (C5b-like C5) by oxygen radicals

1987 • 44 citations

Complement activation with bubble and membrane oxygentors in aortocorpnary bypass grafting

1990 • 37 citations

Complement Activation in Extracorporeal Circulation: Physiological and Pathological Implications

1986 • 33 citations

Rapid in vivo clearance of C5ades arg: a possible protective mechanism against complement-mediated tissue injury.

1981 • 33 citations

Pulmonary response of fifth component of complement-sufficient and -deficient mice to hyperoxia.

1984 • 31 citations

A Sensitive ELISA for the Quantitation of Human C5a in Blood Plasma Using a Monoclonal Antibody

1986 • 27 citations

Complement activation by extracorporeal circulation: effects of precoating a membrane oxygenator circuit with human whole blood

1988 • 22 citations

Rapid and simple measurement of human C5a-des-Arg level in plasma or serum using monoclonal antibodies

1987 • 16 citations

Solid-phase radioimmunoassay of human complement fragment C5a.

1988 • 1 citations