Production of human α₁‐antitrypsin in the milk of transgenic sheep and mice: Targeting expression of CDNA sequences to the mammary gland

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

GERM-LINE TRANSFORMATION OF MICE

1986 • 1,165 citations

Introns increase transcriptional efficiency in transgenic mice.

1988 • 733 citations

Heterologous introns can enhance expression of transgenes in mice.

1991 • 489 citations

Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene

1987 • 479 citations

Genetic Engineering of Livestock

1989 • 437 citations

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.

1991 • 407 citations

Alteration of the quality of milk by expression of sheep β-lactoglobulin in transgenic mice

1987 • 273 citations

Production of Human Tissue Plasminogen Activator in Transgenic Mouse Milk

1987 • 194 citations

High-level expression of biologically active human alpha 1-antitrypsin in the milk of transgenic mice.

1990 • 179 citations

Expression of Human Anti-Hemophilic Factor IX in the Milk of Transgenic Sheep

1989 • 168 citations

Production of transgenic mice, rabbits and pigs by microinjection into pronuclei

1985 • 167 citations

Gene Transfer into Sheep

1988 • 136 citations

Targeting expression to the mammary gland: intronic sequences can enhance the efficiency of gene expression in transgenic mice

1991 • 136 citations

Rabbit β-Casein Promoter Directs Secretion of Human Interleukin-2 into the Milk of Transgenic Rabbits

1990 • 120 citations

Characterization of the gene encoding ovine beta-lactoglobulin

1988 • 116 citations

Bovine AlphaS1-Casein Gene Sequences Direct High Level Expression of Active Human Urokinase in Mouse Milk

1990 • 106 citations

Co-Culture of Ovine Ova with Oviductal Cells in Medium 199

1988 • 102 citations

Pharmaceuticals from transgenic livestock

1987 • 86 citations

Production of transgenic merino sheep by microinjection of ovine metallothionein-ovine growth hormone fusion genes

1989 • 70 citations

Developmental regulation of the sheep β‐lactoglobulin gene in the mammary gland of transgenic mice

1991 • 58 citations

Construction and identification of recombinant plasmids carrying cDNAs coding for ovine αs1-, αs2-, β-, κ-casein and β-lactoglobulin. Nucleotide sequence of αs1-casein cDNA

1985 • 53 citations

Breast Cancer Protein PS2 Synthesis in Mammary Gland of Transgenic Mice and Secretion into Milk

1989 • 52 citations

Production of transgenic mice, rabbits and pigs by microinjection

1986 • 17 citations

Recombinant Proteins of Therapeutic Interest Expressed by Lymphoid Cell Lines Derived from Transgenic Mice

1989 • 17 citations

Enhancement of Factor VIII-von Willebrand Factor Ristocetin Cofactor Activity by Monoclonal Antibodies

1985 • 10 citations