Involvement of a p38 Mitogen-activated Protein Kinase Phosphatase in Protecting Neonatal Rat Cardiac Myocytes from Ischemia

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1994 • 3,285 citations

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1

1995 • 2,080 citations

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

1993 • 1,169 citations

Cardiac Muscle Cell Hypertrophy and Apoptosis Induced by Distinct Members of the p38 Mitogen-activated Protein Kinase Family

1998 • 855 citations

Inhibition of p38 Mitogen-Activated Protein Kinase Decreases Cardiomyocyte Apoptosis and Improves Cardiac Function After Myocardial Ischemia and Reperfusion

1999 • 504 citations

The Mitogen-activated Protein Kinase Phosphatases PAC1, MKP-1, and MKP-2 Have Unique Substrate Specificities and Reduced Activity in Vivo toward the ERK2 sevenmaker Mutation

1996 • 434 citations

The Dual Specificity Phosphatases M3/6 and MKP-3 Are Highly Selective for Inactivation of Distinct Mitogen-activated Protein Kinases

1996 • 385 citations

An Inhibitor of p38 Mitogen-activated Protein Kinase Protects Neonatal Cardiac Myocytes from Ischemia

1999 • 300 citations

Phosphorylation of Tyrosine 182 of p38 Mitogen-activated Protein Kinase Correlates with the Protection of Preconditioning in the Rabbit Heart

1997 • 270 citations

Activation of c-Jun N-Terminal Kinases and p38-Mitogen-activated Protein Kinases in Human Heart Failure Secondary to Ischaemic Heart Disease

1999 • 216 citations

Biomechanical stress‐induced apoptosis in vein grafts involves p38 mitogen‐activated protein kinases

2000 • 155 citations

Role of p38 MAP Kinase in Myocardial Stress

1998 • 103 citations

Activation of the p38 Mitogen-activated Protein Kinase Pathway by Estrogen or by 4-Hydroxytamoxifen Is Coupled to Estrogen Receptor-induced Apoptosis

2000 • 97 citations

A dual function for p38 MAP kinase in hematopoietic cells: involvement in apoptosis and cell activation

1999 • 60 citations