Functional and genetic analysis of annexin VI

Identity of p36K phosphorylated upon Rous sarcoma virus transformation with a protein purified from brush borders; calcium-dependent binding to non-erythroid spectrin and F-actin.

1984 • 541 citations

Inhibition of phospholipase A2 by "lipocortins" and calpactins. An effect of binding to substrate phospholipids.

1987 • 534 citations

Troponin and Parvalbumin Calcium Binding Regions Predicted in Myosin Light Chain and T4 Lysozyme

1975 • 374 citations

Five distinct calcium and phospholipid binding proteins share homology with lipocortin I.

1988 • 364 citations

Characterization of Ca2+-dependent phospholipid binding, vesicle aggregation and membrane fusion by annexins

1990 • 293 citations

INHIBITION OF PHOSPHOLIPASE

1983 • 284 citations

Placental anticoagulant proteins: isolation and comparative characterization of four members of the lipocortin family

1988 • 186 citations

Isolation of mammalian calelectrins: a new class of ubiquitous calcium(2+)-regulated proteins

1984 • 180 citations

Primary structure of the human, membrane-associated Ca2+-binding protein p68 a novel member of a protein family.

1988 • 157 citations

New proteins involved in cell regulation by Ca2+ and phospholipids

1986 • 152 citations

Amino acid sequence analysis of the annexin super‐gene family of proteins

1991 • 152 citations

Modulation of Ca2+ release channel activity from sarcoplasmic reticulum by annexin VI (67-kDa calcimedin).

1990 • 149 citations

Annexin VI is required for budding of clathrin-coated pits

1992 • 144 citations

Novel Calcium-Binding Proteins

1991 • 120 citations

Annexin V: the key to understanding ion selectivity and voltage regulation?

1994 • 112 citations

Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins.

1988 • 109 citations

Calcium(2+)-dependent annexin self-association on membrane surfaces

1991 • 105 citations

Expression of annexins on the surfaces of non-metastatic and metastatic human and rodent tumor cells

1993 • 102 citations

Interactions of annexins with membrane phospholipids

1991 • 102 citations

Crystallization of p68 on lipid monolayers and as three-dimensional single crystals

1989 • 94 citations

Structural evolution of the annexin supergene family

1994 • 88 citations

Isolation and characterization of a novel 68,000-Mr Ca2+-binding protein of lymphocyte plasma membrane

1984 • 84 citations

Calcium channel and membrane fusion activity of synexin and other members of the Annexin gene family

1992 • 81 citations

Endocytosis occurs independently of annexin VI in human A431 cells

1994 • 77 citations

Annexin VI, a marker protein of hepatocytic endosomes.

1994 • 69 citations

Cellular distribution of p68, a new calcium-binding protein from lymphocytes.

1984 • 68 citations

Membrane‐bound annexin V isoforms (CaBP33 and CaBP37) and annexin VI in bovine tissues behave like integral membrane proteins

1992 • 59 citations

Ca2+-dependent phospholipid and arachidonic acid binding by the placental annexins VI and IV

1991 • 57 citations

Alternative splicing of human synexin mRNA in brain, cardiac, and skeletal muscle alters the unique N-terminal domain.

1991 • 55 citations

Expression of annexin VI (p68, 67 kDa-calelectrin) in normal human tissues: evidence for developmental regulation in B- and T-lymphocytes

1991 • 51 citations

Correlation of gene and protein structure of rat and human lipocortin I

1991 • 50 citations

Unique calcium-dependent hydrophobic binding proteins: Possible independent mediators of intracellular calcium distinct from calmodulin

1984 • 49 citations

Differential Subcellular Distribution of p36 (the Heavy Chain of Calpactin I) and Other Annexins in the Adrenal Medulla

1991 • 48 citations

Structure of the human annexin VI gene.

1994 • 48 citations

Expression of annexin VI in A431 carcinoma cells suppresses proliferation: A possible role for annexin VI in cell growth regulation

1994 • 47 citations

Annexins in the endocytic pathway

1994 • 47 citations

Alternative splicing gives rise to two forms of the p68 Ca²⁺ ‐binding protein

1990 • 46 citations

Mechanism of matrix vesicle calcification: characterization of ion channels and the nucleational core of growth plate vesicles

1992 • 44 citations

Calcium-sensitive, lipid-binding cytoskeletal proteins of the human placental microvillar region.

1987 • 42 citations

Coated-vesicle formation in vitro: Conflicting results using different assays

1993 • 42 citations

Molecular cloning of murine p68, a Ca²⁺‐binding protein of the lipocortin family

1988 • 41 citations

Annexin VI is associated with calcium‐sequestering organelles

1991 • 41 citations

Characterization of the human lipocortin-2-encoding multigene family: its structure suggests the existence of a short amino acid unit undergoing duplication

1990 • 40 citations

Interaction of Annexin VI with membranes: Highly restricted dissipation of clustered phospholipids in membranes containing phosphatidylethanolamine

1992 • 38 citations

Annexins IV (p32) and VI (p68) interact with erythrocyte membrane in a calcium-dependent manner

1992 • 36 citations

Cross-linking of lipocortin I and enhancement of its Ca2+ sensitivity by tissue transglutaminase

1989 • 36 citations

Regulation of the sarcoplasmic reticulum Ca²⁺‐release channel requires intact annexin VI

1991 • 33 citations

Diversity in the Annexin Family

1991 • 33 citations

Characterizations of Two Distinct Ca2+-dependent Phospholipid-binding Proteins of 68-kDa Isolated from Human Placenta

1989 • 31 citations

A model of the structure of human annexin VI bound to lipid monolayers

1992 • 30 citations

Organization of the Human Annexin V (ANX5) Gene

1994 • 30 citations

The effect of annexin IV and VI on the fluidity of phosphatidylserine/phosphatidylcholine bilayers studied with the use of 5‐deoxylstearate spin label

1993 • 29 citations

Developmental regulation of calcium‐binding proteins (calelectrins and calpactin I) in mammary glands

1989 • 29 citations

The gene coding for the p68 calcium-binding protein is localised to bands q32?q34 of human chromosome 5, and to mouse chromosome 11

1989 • 26 citations

Molecular cloning of murine p68, a Ca2+-binding protein of the lipocortin family

1988 • 25 citations

Annexins V and VI: major calcium-dependent atrial secretory granule-binding proteins.

1991 • 24 citations

Identification of four lipocortin proteins and phosphorylation of lipocortin I by protein kinase C in cytosols of porcine thyroid cell cultures

1989 • 23 citations

Chromaffin Granules Release Calcium on Contact with Annexin VI: Implications for Exocytosis

1994 • 22 citations

Two 68‐kDa Proteins in Slow Axonal Transport Belong to the 70‐kDa Heat Shock Protein Family and the Annexin Family

1991 • 22 citations

The phosphorylation of p68, a calcium-binding protein associated with the human syncytiotrophoblast submembranous cytoskeleton, is modulated by growth factors, activators of protein kinase C and cyclic AMP

1989 • 21 citations

Calcium-independent phospholipases from guinea pig digestive tract as probes to study the mechanism of lipocortin.

1990 • 20 citations

A growth-dependent post-translational modification of annexin VI

1992 • 20 citations

Alternatively spliced annexin XI transcripts encode proteins that differ near the amino-terminus

1992 • 19 citations

Immunocytochemical localization of 67 KD Ca2+ binding protein (p67) in ventricular, skeletal, and smooth muscle cells.

1992 • 16 citations

Z-DNA-forming sequences at a putative duplication site in the human annexin VI-encoding gene

1994 • 16 citations

Calcium-dependant binding proteins associated with human placental syncytiotrophoblast microvillous cytoskeleton

1987 • 15 citations

Presence of lipocortins I and IV, but not II and VI, in human platelets

1993 • 15 citations

67 k calcimedin (67 kDa) is distinct from p67 calelectrin and lymphocyte 68 kDa Ca2+-binding protein

1988 • 14 citations

Simultaneous phosphorylation of three human calpactins by kinase C

1991 • 13 citations

Isolation and Characterization of an Anticoagulant Protein from Human Placenta

1989 • 13 citations

Effect of 67 kDa calcimedin on caldesmon functioning

1993 • 11 citations

Structure and Expression of cDNA for Calphobindin II, a Human Placental Coagulation Inhibitor

1989 • 11 citations

Axonal transport of actin and actin-binding proteins in the rat sciatic nerve

1994 • 9 citations

Molecular cloning of a novel N-terminal variant of annexin II from rat basophilic leukaemia cells

1994 • 9 citations

Structure and Properties of Calphobindin II, an Anticoagulant Protein from Human Placenta

1990 • 8 citations

Ca2(+)-dependent membrane-binding proteins in normal erythrocytes and erythrocytes from patients with chronic myelogenous leukemia

1990 • 8 citations

An immunological and biochemical comparison of 67 kDa calcimedin and 67 kDa calelectrin

1989 • 7 citations

Purification, characterization, and localization of 70 kDa calcium‐sensitive protein (calelectrin) from mammary glands

1989 • 6 citations