Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo.

ADENOSINE-DEAMINASE DEFICIENCY IN TWO PATIENTS WITH SEVERELY IMPAIRED CELLULAR IMMUNITY

1972 • 1,654 citations

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

1977 • 416 citations

Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency.

1978 • 399 citations

Regulation of Mammalian Deoxyribonucleotide Biosynthesis by Nucleotides as Activators and Inhibitors

1966 • 395 citations

Identification and quantitation of adenine deoxynucleotides in erythrocytes of a patient with adenosine deaminase deficiency and severe combined immunodeficiency.

1978 • 277 citations

A rapid and sensitive high pressure liquid chromatography assay for deoxyribonucleoside triphosphates in cell extracts

1979 • 272 citations

Experimental evaluation of potential anticancer agents. XXI. Scheduling of arabinosylcytosine to take advantage of its S-phase specificity against leukemia cells.

1967 • 242 citations

Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease

1978 • 230 citations

Purinogenic immunodeficiency diseases: selective toxicity of deoxyribonucleosides for T cells.

1978 • 209 citations

Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines.

1979 • 176 citations

Differential Sensitivity of Human Leukemic T Cell Lines and B Cell Lines to Growth Inhibition by Deoxyadenosine

1978 • 167 citations

Nucleosides of 2-Fluoroadenine

1969 • 140 citations

Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation.

1969 • 121 citations

Adenine and Adenosine Are Toxic to Human Lymphoblast Mutants Defective in Purine Salvage Enzymes

1977 • 112 citations

Synthesis and biological activity of selected 2,6-disubstituted(2-deoxy-.alpha.- and -.beta.-D-erythro-pentofuranosyl)purines

1972 • 107 citations

Biochemical basis for differential deoxyadenosine toxicity to T and B lymphoblasts: role for 5'-nucleotidase.

1979 • 99 citations

Specificity of adenosine deaminase toward adenosine and 2′-deoxyadenosine analogues

1966 • 94 citations

Nucleoside analogues : chemistry, biology, and medical applications

1979 • 90 citations

Chemistry and Biology of Nucleosides and Nucleotides

1978 • 88 citations

Differences in deoxyadenosine metabolism in human and mouse lymphocytes.

1980 • 71 citations

Differences in metabolism and cytotoxicity between 9-beta-D arabinofuranosyladenine and 9-beta-D-arabinofuranosyl-2-fluoroadenine in human leukemic lymphoblasts.

1980 • 59 citations

Treatment of acute lymphoblastic leukemia with 2'-deoxycoformycin: clinical and biochemical consequences of adenosine deaminase inhibition.

1979 • 58 citations

[60] Nucleoside deoxyribosyltransferase from Lactobacillus helveticus

1978 • 32 citations

N⁶-(Δ²-Isopentenyl)adenosine: Its Conversion to Inosine, Catalyzed By Adenosine Aminohydrolases From Chicken Bone Marrow and Calf Intestinal Mucosa

1971 • 26 citations

Synthesis and anti-deoxyribonucleic acid virus activity of certain 9-.beta.-D-arabinofuranosyl-2-substituted adenine derivatives

1974 • 9 citations

Metabolism and Toxicity of 9-β-D-Arabinofuranosyladenine in Human Malignant T Cells and B Cells in Tissue Culture

1980 • 6 citations

Ciba Foundation Symposium 68 ‐ Enzyme Defects and Immune Dysfunction

1979 • 3 citations