Astemizole and other H1-antihistaminic drug treatment of asthma

I. The Croonian Lecture

1810 • 634 citations

COMPARISON OF WEIGHT REDUCTION WITH METOPROLOL IN TREATMENT OF HYPERTENSION IN YOUNG OVERWEIGHT PATIENTS

1985 • 370 citations

The quantitative estimation of histamine in the blood

1937 • 283 citations

The nature of the vaso‐dilator constituents of certain tissue extracts

1927 • 243 citations

REACTIONS OF ISOLATED HUMAN ASTHMATIC LUNG AND BRONCHIAL TISSUE TO A SPECIFIC ANTIGEN HISTAMINE RELEASE AND MUSCULAR CONTRACTION

1951 • 222 citations

PREVENTION OF ENDEMIC GOITRE

1965 • 221 citations

Determinants of allergen-induced asthma: dose of allergen, circulating IgE antibody concentration, and bronchial responsiveness to inhaled histamine.

1979 • 207 citations

Exercise-induced release of histamine and neutrophil chemotactic factor in atopic asthmatics

1982 • 194 citations

Interaction between hyperosmolar and IgE-mediated histamine release from basophils and mast cells.

1984 • 187 citations

Pharmacokinetics and biotransformation studies of terfenadine in man.

1982 • 125 citations

Bronchodilating activity of an H blocker, chlorpheniramine

1977 • 123 citations

Terfenadine in exercise induced asthma.

1984 • 109 citations

INHIBITION OF HISTAMINE RELEASE FROM HUMAN LUNG in vitro BY ANTIHISTAMINES AND RELATED DRUGS

1980 • 106 citations

In vitro and in vivo binding characteristics of a new long-acting histamine H1 antagonist, astemizole.

1982 • 97 citations

Astemizole, a potent histamine H1‐receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels.

1984 • 87 citations

The relationship of plasma histamine to the activity of bronchial asthma

1977 • 86 citations

Histamine levels in plasma, blood, and urine in severe asthma, and the effect of corticosteroid treatment.

1976 • 84 citations

Antihistamines in Bronchial Asthma

1949 • 82 citations

Concentration effect relationships of infused histamine in normal volunteers

1982 • 71 citations

Pathogenesis of asthma

1984 • 70 citations

Bronchial histamine reactivity: its relationship to the reactivity of the bronchi to allergens

1976 • 69 citations

Inhaled antihistamines--bronchodilatation and effects on histamine- and methacholine-induced bronchoconstriction.

1978 • 59 citations

Plasma Histamine and Catecholamines in Stable Asthmatic Subjects

1982 • 59 citations

The Role of Histamine Receptors in Asthma

1981 • 57 citations

Protection tests on bronchial allergen challenge with disodium cromoglycate and thiazinamium

1970 • 51 citations

Exercise and isocapnic hyperventilation-induced bronchoconstriction in asthma: Relevance of circulating basophils to measurements of plasma histamine

1984 • 51 citations

Effect of inhaled H1 and H2 receptor antagonist in normal and asthmatic subjects.

1980 • 47 citations

The effect of astemizole on exercise-induced asthma.

1984 • 43 citations

The role of histamine and its receptors in the pathogenesis of asthma

1983 • 43 citations

Comparison of plasma histamine and cyclic nucleotides after antigen and methacholine inhalation in man

1980 • 38 citations

Effect of antihistamines and antiallergic drugs on responses to allergen and histamine provocation tests in asthma.

1984 • 36 citations

The effect of astemizole on exercise-induced asthma

1984 • 32 citations

Effect of an inhaled antihistamine (clemastine) as a bronchodilator and as a maintenance treatment in asthma.

1979 • 28 citations

The bronchodilator effects of chlorpheniramine in childhood asthma

1979 • 27 citations

THE RÔLE OF HISTAMINE IN CANINE ANAPHYLACTIC SHOCK

1936 • 20 citations

Increased antigen-induced local and systemic mediator release in rhinitis subjects with pulmonary symptoms in the pollen season

1984 • 17 citations

144 Airway hyperreactivity and mediator release in clinical models of asthma

1985 • 17 citations

The Protective Property of Equipotent Bronchodilating Doses of Inhaled KWD 2131 and Terbutaline against Allergen-Induced Bronchospasm

1982 • 7 citations

231 Immunological studies of antigen-induced late asthmatic reactions

1983 • 5 citations