Altered transcriptional regulation of phosphoenolpyruvate carboxykinase in rats following endotoxin treatment.

Statistical principles in experimental design.

1962 • 27,228 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

Statistical Principles in Experimental Design

1964 • 8,376 citations

Bacterial lipopolysaccharides : extraction with phenol-water and further applications of the procedure

1965 • 2,566 citations

Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF)

1990 • 1,307 citations

Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.

1979 • 975 citations

Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas.

1986 • 701 citations

Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.

1984 • 436 citations

Identification of a Sequence in the PEPCK Gene That Mediates a Negative Effect of Insulin on Transcription

1990 • 369 citations

Inhibition of transcription of the phosphoenolpyruvate carboxykinase gene by insulin

1983 • 366 citations

The Enzymatic Carboxylation of Phosphoenolpyruvate

1966 • 353 citations

Regulation of hepatic acute phase plasma protein genes by hepatocyte stimulating factors and other mediators of inflammation.

1990 • 335 citations

Endotoxemia elicits increased circulating beta 2-IFN/IL-6 in man.

1989 • 323 citations

Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression.

1987 • 320 citations

Gluconeogenesis

1972 • 317 citations

IL-6 modulates the synthesis of a specific set of acute phase plasma proteins in vivo.

1989 • 307 citations

Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene.

1990 • 299 citations

The genes of hepatic glucose metabolism.

1990 • 271 citations

Rat hepatic cytosolic phosphoenolpyruvate carboxykinase (GTP). Structures of the protein, messenger RNA, and gene.

1985 • 231 citations

IL-6/IFN-beta-2 as a circulating hormone. Induction by cytokine administration in humans.

1989 • 201 citations

The acute phase response of the liver in inflammation.

1990 • 171 citations

Cyclic AMP stabilizes the mRNA for phosphoenolpyruvate carboxykinase (GTP) against degradation.

1988 • 165 citations

Increase in level of functional messenger RNA coding for phosphoenolpyruvate carboxykinase (GTP) during induction by cyclic adenosine 3':5'-monophosphate.

1977 • 133 citations

Interleukin-6 Affects Insulin Secretion and Glucose Metabolism of Rat Pancreatic Isletsin Vitro*

1990 • 127 citations

3' noncoding region of phosphoenolpyruvate carboxykinase mRNA contains a glucocorticoid-responsive mRNA-stabilizing element.

1989 • 113 citations

Interleukin 1: a regulatory role in glucocorticoid-regulated hepatic metabolism.

1986 • 95 citations

N6,O2'-dibutyryl cycle AMP and glucose regulate the amount of messenger RNA coding for hepatic phosphoenolpyruvate carboxykinase (GTP).

1982 • 91 citations

Effects of adenosine cyclic monophosphate, dexamethasone, and insulin on phosphoenolpyruvate carboxykinase synthesis in Reuber H-35 hepatoma cells

1975 • 89 citations

Characterization of a Complex Glucocorticoid Response Unit in the Phosphoenolpyruvate Carboxykinase Gene

1990 • 89 citations

Glucocorticoids and the regulation of phosphoenolpyruvate carboxykinase (guanosine triphosphate) in the rat

1975 • 87 citations

Effects of Endotoxin on Gluconeogenesis, Glycogen Synthesis, and Liver Glycogen Synthase in Mice

1973 • 83 citations

Alterations in translatable messenger RNA coding for phosphoenolpyruvate carboxykinase (GTP) in rat liver cytosol during deinduction.

1978 • 62 citations

Human recombinant IL-1 alters glucocorticoid receptor function in Reuber hepatoma cells.

1988 • 58 citations

Regulation of rat liver phosphoenolpyruvate carboxykinase (GTP) messenger ribonucleic acid activity by N6,O2'-dibutyryladenosine 3',5'-phosphate

1981 • 52 citations

Endotoxin-enhanced secretion of macrophage insulin-like activity.

1980 • 36 citations

Inhibition of Hepatic Enzyme Induction as a Sensitive Assay for Endotoxin

1968 • 35 citations

Influence of endotoxin treatment on dexamethasone induction of hepatic phosphoenolpyruvate carboxykinase

1983 • 30 citations

Study of Inhibition of Induction of Phosphoenolpyruvate Carboxykinase by Endotoxin with Radial Immunodiffusion

1972 • 25 citations

Purification and NH2-terminal Amino-acid-sequence of a New T-cell Derived Lymphokine With Growth-factor Activity for B-cell Hybridomas

1987 • 22 citations

Effect of lipopolysaccharide and lipid A on mouse liver pyruvate kinase activity

1975 • 14 citations

Monokines Mediate Decreased Hepatic Glucocorticoid Binding in Endotoxemia

1987 • 14 citations

Mechanism of Action of Interferon‐β₂/Interleukin‐6 on Induction of Hepatic Liver Enzymes^a

1989 • 11 citations

Failure of glucagon to induce hepatic phosphoenolpyruvate carboxykinase in endotoxic shock.

1988 • 11 citations

Antiglucocorticoid effects of endotoxin.

1984 • 8 citations

The molecular biology of insulin action on protein synthesis.

1987 • 8 citations

Cytokines and Acute Phase Protein Expression

2024 • 6 citations

METABOLIC AND ENDOCRINE ALTERATIONS FOLLOWING ENDOTOXIN ADMINISTRATION IN NORMAL AND DIABETIC RATS

1981 • 6 citations