Effect of Two- and Three-Locus Linkage Disequilibrium on the Power to Detect Marker/Phenotype Associations

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

1993 • 3,693 citations

Patterns of linkage disequilibrium in the human genome

2002 • 1,132 citations

Genetic Data Analysis II. By Bruce S. Weir, Sunderland, Massachusetts. Sinauer Associates, Inc.445 pages. ISBN 0-87893-902-4.

1996 • 947 citations

Testing Association of Statistically Inferred Haplotypes with Discrete and Continuous Traits in Samples of Unrelated Individuals

2002 • 677 citations

Haplotype blocks and linkage disequilibrium in the human genome

2003 • 629 citations

Haplotypes vs single marker linkage disequilibrium tests: what do we gain?

2001 • 444 citations

Genetic Analysis of Case/Control Data Using Estimated Haplotype Frequencies: Application to APOE Locus Variation and Alzheimer's Disease

2001 • 432 citations

A first-generation linkage disequilibrium map of human chromosome 22

2002 • 412 citations

The Power of Association Studies to Detect the Contribution of Candidate Genetic Loci to Variation in Complex Traits

1999 • 406 citations

Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots

2003 • 291 citations

ON THE THEORY OF RANDOM MATING

1952 • 142 citations

Issues concerning association studies for fine mapping a susceptibility gene for a complex disease

2001 • 51 citations

A classical setting for associations between markers and loci affecting quantitative traits

1999 • 40 citations

Third order linkage disequilibrium*

1984 • 37 citations

HLA Haplotype Associations with Disease

1979 • 32 citations

Non-Random Association of Neutral Linked Genes in Finite Populations

1976 • 29 citations

Clinical chemistry of common apolipoprotein E isoforms

1996 • 28 citations

Association Studies under General Disease Models

2001 • 18 citations