High and low doses of haptens dictate whether dermal or epidermal antigen‐presenting cells promote contact hypersensitivity

Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB.

1980 • 983 citations

Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization.

1990 • 543 citations

Langerhans cells form a reticuloepithelial trap for external contact antigens

1976 • 283 citations

Phenotypic and functional characteristics of in vivo-activated Langerhans cells.

1990 • 238 citations

Natural and Perturbed Distributions of Langerhans Cells: Responses to Ultraviolet Light, Heterotopic Skin Grafting, and Dinitrofluorobenzene Sensitization

1980 • 151 citations

Genetic basis of ultraviolet-B effects on contact hypersensitivity

1988 • 114 citations

Antigen-Presenting Cells in the Induction of Contact Hypersensitivity in Mice: Evidence that Langerhans Cells Are Sufficient but not Required

1989 • 89 citations

Studies of Contact Hypersensitivity Induction in Mice with Optimal Sensitizing Doses of Hapten

1993 • 45 citations

Sensitization through carcinogen-induced Langerhans cell-deficient skin activates specific long-lived suppressor cells for both cellular and humoral immunity

1987 • 44 citations

DETECTION OF DONOR-DERIVED CELLS BY POLYMERASE CHAIN REACTION IN NEONATALLY TOLERANT MICE

1995 • 40 citations

Fresh and cultured Langerhans cells display differential capacities to activate hapten-specific T cells.

1993 • 40 citations

Role of dermal cells from normal and ultraviolet B-damaged skin in induction of contact hypersensitivity and tolerance.

1994 • 35 citations

Immunology/Inflammation of the Skin—A 50-Year Perspective

1989 • 31 citations

Ultrastructural studies bearing on the mechanism of UVB-impaired induction of contact hypersensitivity to DNCB in man

1993 • 27 citations

Analysis of Dose Response of Trinitrochlorobenzene Contact Hypersensitivity Induction in Mice: Pretreatment with Cyclophosphamide Reveals an Optimal Sensitizing Dose

1990 • 24 citations

Induction of Tolerance to Urushiol by Epicutaneous Application of This Hapten on Dinitrofluorobenzene-Treated Skin

1985 • 20 citations

Cellular and Molecular Mechanisms in the Induction Phase of Contact Sensitivity

1995 • 16 citations

Sensitizing capacity of Langerhans' cells obtained from ultraviolet-B-exposed murine skin.

1995 • 15 citations

Effects of immunological responsiveness on Langerhans cell behavior in contact sensitization

1994 • 8 citations

Immunology/Inflammation of the Skin--A 50-Year Perspective.

1989 • 5 citations