Chemical modification of radiation effects

Radiation and High-Dose Metronidazole in Supratentorial Glioblastomas

1976 • 309 citations

Modification of radiation injury to normal tissues by chemotherapeutic agents

1975 • 273 citations

Differential Chemoprotection of Normal and Malignant Tissues<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1969 • 266 citations

Clinical testing of the radiosensitizer Ro 07-0582: Experience with multiple doses

1977 • 264 citations

Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of the oral cavity and oropharynx: a randomized study

1976 • 257 citations

Quantification of combined radiation therapy and chemotherapy effects on critical normal tissues

1976 • 253 citations

Radiation pneumonitis: A new approach to the derivation of time-dose factors

1973 • 238 citations

Electron Affinic Sensitization: V. Radiosensitization of Hypoxic Bacteria and Mammalian Cells in Vitro by Some Nitroimidazoles and Nitropyrazoles

1974 • 229 citations

Hydrated electrons and radiobiological sensitisation

1963 • 211 citations

Hypoxic Sensitizers: Radiobiological Studies at the Cellular Level

1975 • 205 citations

Protective Mechanisms in Ionizing Radiation Injury

1953 • 193 citations

Synergistic interaction of anticancer agents: a cellular perspective.

1975 • 190 citations

CHEMICAL RADIOSENSITIZATION OF HYPOXIC CELLS

1973 • 166 citations

Chemoprotection against Three Modes of Radiation Death in the Mouse

1969 • 143 citations

Radioprotection of tumor and normal tissues by thiophosphate compounds

1973 • 136 citations

Radiobiolgoical and biochemical studies of thiophosphate radioprotective compounds related to cysteamine.

1971 • 135 citations

Selective Radiosensitization of the Hypoxic Cells of Mouse Tumors with the Nitroimidazoles Metronidazole and Ro 7-0582

1975 • 128 citations

Molecular Radiobiology of Human Cell Lines: V. Comparative Radiosensitizing Properties of 5-Halodeoxycytidines and 5-Halodeoxyuridines

1963 • 127 citations

Clinical testing of the radiosensitiser Ro-07-0582 I. dose tolerance, serum and tumour concentrations

1976 • 125 citations

Clinical testing of the radiosensitiser Ro-07-0582 III. Response of tumours

1976 • 121 citations

Metronidazole (“Flagyl”). A radiosensitizer of hypoxic cells

1974 • 118 citations

Tests of Two Electron-Affinic Radiosensitizers in Vivo Using Regrowth of an Experimental Carcinoma

1975 • 115 citations

Increase in Radiosensitivity to Ionizing Radiation Related to Replacement of Thymidine in Mammalian Cells with 5-Bromodeoxyuridine

1965 • 112 citations

Radiobiological and Biochemical Studies of Thiophosphate Radioprotective Compounds Related to Cysteamine

1971 • 105 citations

Hypoxic Cell Radiosensitizers: Comparative Tests of Some Electron Affinic Compounds Using Epidermal Cell Survival in Vivo

1974 • 104 citations

Localized ewing's sarcoma—treatment and results

1974 • 102 citations

Biological factors affecting the radioprotective efficiency of S-2-[3-aminopropylamino]ethylphosphorothioic acid (WR-2721): LD 50(7) doses.

1971 • 98 citations

Distribution of 35 S-Labeled WR-2721 in Normal and Malignant Tissues of the Mouse

1976 • 97 citations

Effectiveness of nitrofuran derivatives in sensitizing hypoxic mammalian cells to X rays

1973 • 95 citations

Demonstration of radiosensitization of hypoxic cells in solid tumours by metronidazole

1974 • 90 citations

Radiosensitization of Malignant Brain Tumours with Bromouridine (Thymidine Analogue)

1969 • 85 citations

Phase 1 Study of High-Dose Metronidazole: A SpecificIn VivoandIn VitroRadiosensitizer of Hypoxic Cells

1975 • 81 citations

Clinical testing of the radiosensitiser Ro-07-0582 II. Radiosensitisation of normal and hypoxic skin

1976 • 75 citations

Radiosensitization of C3H Mouse Mammary Tumours by a 2-Nitroimidazole Drug

1974 • 68 citations

Prediction of the Effective Radioprotective Dose of WR-2721 in Humans through an Interspecies Tissue Distribution Study

1976 • 68 citations

S-[2-(.omega.-Aminoalkylamino)ethyl] dihydrogen phosphorothioates and related compounds as potential antiradiation agents

1969 • 67 citations

Biological Factors Affecting the Radioprotective Efficiency of S-2-[3-Aminopropylamino] Ethylphosphorothioic Acid (WR-2721). LD 50(30) Doses

1970 • 65 citations

Preferential Radiosensitization of Mouse Sarcoma Relative to Normal Skin by Chronic Intra-Arterial Infusion of Halogenated Pyrimidine Analogs<xref ref-type="fn" rid="FN2">2</xref>

1971 • 63 citations

Response of a Murine Solid Tumor toIn VivoCombined Chemotherapy and Irradiation

1973 • 53 citations

Protection of normal tissues by WR2721 during fractionated irradiation

1976 • 49 citations

Differential Radioprotection of Euoxic and Hypoxic Mouse Mammary Tumors by a Thiophosphate Compound

1974 • 42 citations

Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results

1975 • 40 citations

The Response of a Transplantable Tumor to Fractionated Irradiation: 1. X Rays and the Hypoxic Cell Radiosensitizer Ro-07-0582

1976 • 40 citations

A Clinical Study of Chemical Radiosensitization1

2015 • 40 citations

Effect of Oxygen in Mammalian Cells Sensitized to Radiation by Incorporation of 5-Bromodeoxyuridine into the DNA

1963 • 34 citations

Nitroheterocyclic drugs as selective radiosensitizers of hypoxic mammalian cells.

1974 • 33 citations

Chemical protection against ionising radiation.

1961 • 31 citations

In Vivo Testing of Hypoxic Cell Radiosensitizers

1975 • 30 citations

Radiosensitization of C₃H mouse mammary tumours using fractionated doses of X rays with the drug Ro-07–0582

1976 • 30 citations

Modification of the Response of Mouse Skin to X-Irradiation by Bleomycin Treatment

1975 • 27 citations

Modification of the response of mouse skin to x-irradiation by bleomycin treatment.

1975 • 25 citations

Effect of Radioprotective Drugs on the Therapeutic Ratio for a Mouse Tumor System

1973 • 25 citations

Combined Radiosensitizer Infusion and Irradiation of Osteogenic Sarcomas

1975 • 21 citations

Exploitation of Kinetic Differences between Normal and Malignant Cells

1975 • 19 citations

Skin reaction — a quantitative system for measurement of radiosensitisation in man

1976 • 11 citations

Influence of Aminoethylisothiouronium Bromide·hydrobromide and Hypoxia on Recovery from Radiation Injury in Mice

1966 • 10 citations

CHEMICAL PROTECTION AGAINST IONIZING RADIATIONS

1956 • 9 citations

Radical partial renal irradiation.An alternative to partial nephrectomy in bilateral Wilms' tumor

1976 • 5 citations

Prolonged carotid arterial radiosensitizer infusion and radiation therapy of mouse gliomas.

1972 • 5 citations