Review: Putative mutagens and carcinogens in foods III. Butylated hydroxytoluene (BHT)

Inhibition of Carcinogenic and Toxic Effects of Polycyclic Hydrocarbons by Phenolic Anti-oxidants and Ethoxyquin<xref ref-type="fn" rid="FN2">2</xref>

1972 • 352 citations

Free Radical Theory of Aging: Effect of Free Radical Reaction Inhibitors on the Mortality Rate of Male LAF1 Mice

1968 • 339 citations

Handbook of Food Additives

1973 • 321 citations

THE MUTAGENIC ACTIVITY OF 61 AGENTS AS DETERMINED BY THE MICRONUCLEUS, SALMONELLA, AND SPERM ABNORMALITY ASSAYS

1979 • 283 citations

Chemical Mutagens in the Human Environment

1968 • 224 citations

The effects of antioxidants on skin tumor initiation and aryl hydrocarbon hydroxylase.

1977 • 201 citations

Antioxidants and carcinogenesis: butylated hydroxytoluene, but not diphenyl-p-phenylenediamine, inhibits cancer induction by N-2-fluorenylacetamide and by N-hydroxy-N-2-fluorenylacetamide in rats

1973 • 157 citations

Carcinogen-Induced Chromosomal Breakage Decreased by Antioxidants

1973 • 149 citations

Enhancing effects of phenobarbitone and butylated hydroxytoluene on 2-acetylaminofluorene-induced hepatic tumorigenesis in the rat

1977 • 138 citations

The Transplacental Migration and Accumulation in Blood of Volatile Organic Constituents

1976 • 132 citations

Butylated hydroxytoluene (BHT): A review

1982 • 132 citations

Enhancement of Urethan Tumorigenesis in Mouse Lung by Butylated Hydroxytoluene2

1977 • 127 citations

Antioxidants reduce the mutagenic effect of malonaldehyde and β-propiolactone

1979 • 125 citations

Major Effect on Susceptibility to Urethan-lnduced Pulmonary Adenoma by a Single Gene in BALB/cBy Mice<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 121 citations

Dose-response study of hemorrhagic death by dietary butylated hydroxytoluene (BHT) in male rats

1978 • 119 citations

Lung Damage in Mice Following Intraperitoneal Injection of Butylated Hydroxytoluene

1972 • 110 citations

Inhibitory effect of butylated hydroxytoluene (BHT) on intestinal carcinogenesis in rats by azoxymethane

1977 • 96 citations

Effect of retinoic acid, butylated hydroxytoluene, selenium and sorbic acid on azo-dye hepatocarcinogenesis

1980 • 96 citations

Butylated Hydroxytoluene Inactivated Lipid-Containing Viruses

1975 • 89 citations

Use of Spin Labels to Evaluate Effects of Cold Shock and Osmolality on Sperm

1978 • 86 citations

Potentiation of diffuse lung damage by oxygen: determining variables.

1981 • 76 citations

Perturbations of the dynamics of lipid alkyl chains in membrane systems: Effect on the activity of membrane-bound enzymes

1974 • 75 citations

Effect of the antioxidant butylated hydroxytoluene (BHT) on the metabolism of the carcinogens N-2-fluorenylacetamide and N-hydroxy-N-2-fluorenylacetamide

1973 • 74 citations

Enhancement of tumor formation in mouse lung by dietary butylated hydroxytoluene

1981 • 73 citations

THE EFFECT OF THE LEVEL OF DIETARY FAT ON THE TOXICITY OF PHENOLIC ANTIOXIDANTS

1959 • 73 citations

Effects of drug metabolism inhibitors on butylated hydroxytoluene-induced pulmonary toxicity in mice

1980 • 70 citations

Enhancement of Oncogenesis in C3H/10T1/2 Mouse Embryo Cell Cultures by Saccharin

1978 • 70 citations

Quantitative correspondence between the in vivo and in vitro activity of teratogenic agents.

1982 • 66 citations

Effects of butylated hydroxytoluene on the ultrastructure of rat hepatocytes.

1967 • 65 citations

Binding of (3H)benzo(a)pyrene to DNA in cultured human bronchus.

1976 • 64 citations

Effect of phenolic antioxidants on the mutagenicity of aflatoxin B1

1980 • 64 citations

Prevention of butylated hydroxytoluene-induced lung damage in mice by cedar terpene administration

1979 • 61 citations

Ultrastructural and biochemical changes in the liver of monkeys given butylated hydroxytoluene and butylated hydroxyanisole

1972 • 59 citations

Modification of the acute toxicity of mutagenic and carcinogenic chemicals in the mouse by prefeeding with antioxidants

1973 • 58 citations

Butylated Hydroxytoluene Protects Chickens Exposed to Newcastle Disease Virus

1977 • 55 citations

Butylate hydroxytoluene pretreatment protects against cytotoxicity and reduces covalent binding of aflatoxin B1 in primary hepatocyte cultures

1981 • 54 citations

BHT oxidase. A liver-microsomal enzyme induced by the treatment of rats with butylated hydroxytoluene

1967 • 49 citations

Enhancement of adenoma formation in mouse lung by butylated hydroxytoluene

1979 • 47 citations

Inhibition of Promutagen Activation by the Antioxidants Butylated Hydroxyanisole and Butylated Hydroxytoluene

1979 • 45 citations

Progress report on multigeneration reproduction studies in rats fed butylated hydroxytoluene (BHT)

1965 • 44 citations

Pulmonary toxicity of butylated hydroxytoluene and related alkylphenols: Structural requirements for toxic potency in mice*1

1982 • 43 citations

The effect of butylated hydroxyanisole and butylated hydroxytoluene on behavioral development of mice

1974 • 43 citations

Modification of lung tumor development in A/J mice

1981 • 42 citations

Effects of the Food Additive Butylated Hydroxytoluene on Monolayer Cultures of Primate Cells

1967 • 40 citations

Studies on the mechanism of inhibition of 2-acetylaminofluorene toxicity by butylated hydroxytoluene

1976 • 39 citations

Antioxidants and the mutagenicity of benzo(a) pyrene and some derivatives

1978 • 39 citations

Synthetic Organic Chemicals: United States Production and Sales, 1976.

1977 • 36 citations

Cytotoxicity of butylated hydroxytoluene and butylated hydroxyanisole in cultured heart cells

1978 • 34 citations

Selective Sex-Related Modification of Diethylnitrosamine-lnduced Carcinogenesis in BALB/c Mice by Concomitant Administration of Butylated Hydroxytoluene2

1978 • 34 citations

Benzo(a)pyrene metabolism in mouse epidermis. Analysis by high pressure liquid chromatography and DNA binding

1977 • 33 citations

Developmental neurobehavioural toxicity of butylated hydroxytoluene in rats

1981 • 29 citations

Long-Term Antioxidant Exposure Effects on Female Primates

1976 • 27 citations

Cytogenetic activity of some common antioxidants and their interaction with x-rays

1979 • 26 citations

Species and strain differences in the butylated hydroxytoluene (BHT)-producing induction of hepatic drug oxidation enzymes.

1980 • 26 citations

Radiosensitization ofDrosophilaSperm by Commonly Used Food Additives–Butylated Hydroxyanisole and Butylated Hydroxytoluene

1974 • 25 citations

A re-examination of the possible teratogenic effects of butylated hydroxytoluene (BHT) and its effect on the reproductive capacity of the mouse

1965 • 24 citations

Nitrous acid mutagenesis of duplex DNA as a three-component system

1979 • 23 citations

Butylated hydroxytoluene: Tumor-promoting activity in anin vitro two-stage carcinogenesis assay

1982 • 22 citations

Involvements of cyclic nucleotide systems in enlarged mice lungs produced by butylated hydroxytoluene

1978 • 22 citations

Effect of inhibitors of tumorigenesis on the formation of O6-methylguanine in the colon of 1,2-dimethylhydrazine-treated rats.

1981 • 21 citations

Strain differences in butylated hydroxytoluene-induced deaths in male mice

1981 • 20 citations

Selective inhibition of liver-cell proliferation by CFT 1201 and SKF 525 A

1972 • 20 citations

Inhibition by butylated hydroxytoluene of excision repair synthesis and semiconservative DNA synthesis

1978 • 19 citations

The effects of butylated hydroxytoluene on the cell cycle and chromosome morphology of phytohaemagglutinin-stimulated leucocyte cultures

1974 • 18 citations

Altered phosphorylation of lung proteins following administration of Butylated Hydroxytoluene (BHT) to mice

1979 • 18 citations

Hydroxylation of benzo[a]pyrene and binding of (−)trans 5-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to deoxyribonucleic acid catalyzed by purified forms of rabbit liver microsomal cytochrome P-450

1980 • 17 citations

Effects of butylated hydroxyanisole on the aryl hydrocarbon hydroxylase of rats and mice

1981 • 16 citations

Radiosensitization of EL4 lymphoma cells by a commonly used food additive-butylated hydroxytoluene (BHT)

1973 • 13 citations

Modification of the mutagenic activity of propane sultone by some phenolic antioxidants

1981 • 9 citations

Evidence for translational control of the binding of 7,12-dimethylbenz[a]anthracene to DNA of murine epidermal cell in culture

1979 • 6 citations

Changes in tumor-specific nuclear antigen activity in carcinogen-treated colon by tumor promoter and carcinogen inhibitors.

1981 • 3 citations