Identification of vancomycin resistance protein VanA as a D-alanine:D-alanine ligase of altered substrate specificity

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Plasmid-Mediated Resistance to Vancomycin and Teicoplanin in Enterococcus Faecium

1988 • 1,441 citations

Structure, biochemistry and mechanism of action of glycopeptide antibiotics

1989 • 671 citations

THE STRUCTURE AND MODE OF ACTION OF GLYCOPEPTIDE ANTIBIOTICS OF THE VANCOMYCIN GROUP

1984 • 490 citations

Transferable vancomycin and teicoplanin resistance in Enterococcus faecium

1989 • 315 citations

Modifications of the acyl-<scp>d</scp>-alanyl-<scp>d</scp>-alanine terminus affecting complex-formation with vancomycin

1971 • 258 citations

Inducible, transferable resistance to vancomycin in Enterococcus faecalis A256

1989 • 198 citations

Resistance of enterococci to glycopeptides

1990 • 193 citations

Inducible Resistance to Vancomycin in Enterococcus faecium D366

1989 • 147 citations

The VANA glycopeptide resistance protein is related to d-alanyl-d-alanine ligase cell wall biosynthesis enzymes

1990 • 141 citations

The Enzymatic Synthesis of d-Alanyl-d-alanine

1962 • 134 citations

Existence of two D-alanine:D-alanine ligases in Escherichia coli: cloning and sequencing of the ddlA gene and purification and characterization of the DdlA and DdlB enzymes

1991 • 129 citations

Characterization of vancomycin resistance in Enterococcus faecium and Enterococcus faecalis

1989 • 104 citations

The Enzymatic Synthesis of d-Alanyl-d-alanine

1962 • 104 citations

D-amino acid aminotransferase of Bacillus sphaericus. Enzymologic and spectrometric properties.

1975 • 101 citations

Rotational resonance determination of the structure of an enzyme-inhibitor complex: phosphorylation of an (aminoalkyl)phosphinate inhibitor of D-alanyl-D-alanine ligase by ATP

1990 • 84 citations

Reverse-phase high-pressure liquid chromatography of uridine diphosphate N-acetylmuramyl peptide precursors of bacterial cell wall peptidoglycan

1981 • 84 citations

Mechanism of resistance to vancomycin in Enterococcus faecium D366 and Enterococcus faecalis A256

1990 • 84 citations

Purification and characterization of the D-alanyl-D-alanine-adding enzyme from Escherichia coli

1990 • 74 citations

Streptomycin Biosynthesis and Metabolism

1970 • 70 citations

Isolation, cloning, and sequencing of the Salmonella typhimurium ddlA gene with purification and characterization of its product, D-alanine:D-alanine ligase (ADP forming)

1988 • 64 citations

Enzymatic Synthesis of Analogs of the Cell-Wall Precursor. I. Kinetics and Specificity of Uridine Diphospho-N-acetylmuramyl-L-alanyl-D- glutamyl-L-lysine:D-Alanyl-D-alanine Ligase (Adenosine Diphosphate) from Streptococcus faecalis R^*

1965 • 59 citations

Reversal by a specific peptide (diacetyl-αγ-<scp>l</scp>-diaminobutyryl-<scp>d</scp>-alanine) of vancomycin inhibition in intact bacteria and cell-free preparations

1972 • 38 citations

Comparison of vancomycin-inducible proteins from four strains of Enterococci

1990 • 37 citations

Steric effects on penicillin-sensitive peptidoglycan synthesis in a membrane-wall system from Gaffkya homari

1976 • 21 citations

d-alanine-d-alanine ligase (ADP) from Salmonella typhimurium

1989 • 13 citations