Frequent monoallelic loss of D13S319 in multiple myeloma patients shown by interphase fluorescence in situ hybridization

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1986 • 2,968 citations

Current Protocols in Human Genetics

2001 • 1,023 citations

Multiple Myeloma: Increasing Evidence for a Multistep Transformation Process

1998 • 761 citations

The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis

1985 • 419 citations

Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities

1995 • 418 citations

Cytogenetic findings in 200 patients with multiple myeloma

1995 • 378 citations

Altered Expression of the Retinoblastoma Gene Product in Human Sarcomas

1990 • 221 citations

Plasma cell karyotype in multiple myeloma

1988 • 174 citations

MULTIPLE MYELOMA: ALMOST ALL PATIENTS ARE CYTOGENETICALLY ABNORMAL

1996 • 161 citations

Interphase fluorescence in situ hybridization identifies chromosomal abnormalities in plasma cells from patients with monoclonal gammopathy of undetermined significance

1995 • 143 citations

The Genetic Basis of Cancer

1995 • 140 citations

13q deletions in lymphoid malignancies

1995 • 137 citations

Evidence for a new tumour suppressor locus (DBM) in human B–cell neoplasia telomeric to the retinoblastoma gene

1993 • 135 citations

Cloning and Gene Mapping of the Chromosome 13q14 Region Deleted in Chronic Lymphocytic Leukemia

1997 • 130 citations

High frequency of monoallelic retinoblastoma gene deletion in B-cell chronic lymphoid leukemia shown by interphase cytogenetics

1993 • 127 citations

Cellular DNA content as a marker of human multiple myeloma

1980 • 113 citations

Minimal region of loss at 13q14 in B-cell chronic lymphocytic leukemia

1996 • 112 citations

Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: evidence for a role of an adjacent locus.

1993 • 102 citations

Deletion of the retinoblastoma gene in multiple myeloma.

1994 • 90 citations

Interphase fluorescence in situ hybridization (FISH) as a powerful tool for the detection of aneuploidy in multiple myeloma.

1995 • 85 citations

Heterogeneity of deletions involving RB-1 and the D13S25 locus in B-cell chronic lymphocytic leukemia revealed by fluorescence in situ hybridization.

1995 • 66 citations

Detection of numerical aberrations in hematologic neoplasias by fluorescence in situ hybridization.

1997 • 16 citations