CD81 on B cells promotes interleukin 4 secretion and antibody production during T helper type 2 immune responses

Cloning of a new cytokine that induces IFN-γ production by T cells

1995 • 2,584 citations

Selected methods in cellular immunology

1981 • 1,915 citations

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 • 1,695 citations

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

1995 • 1,560 citations

The tetraspanin superfamily: molecular facilitators

1997 • 938 citations

Interleukin (IL)-6 Directs the Differentiation of IL-4–producing CD4+ T Cells

1997 • 823 citations

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model.

1995 • 768 citations

Interferon‐γ‐inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin‐12 for interferon‐γ production

1996 • 606 citations

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4

1995 • 577 citations

IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12.

1997 • 528 citations

The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity.

1992 • 518 citations

CD81 (TAPA-1): A MOLECULE INVOLVED IN SIGNAL TRANSDUCTION AND CELL ADHESION IN THE IMMUNE SYSTEM

1998 • 507 citations

T cell genetic background determines default T helper phenotype development in vitro.

1995 • 466 citations

Developmental commitment to the Th2 lineage by extinction of IL-12 signaling

1995 • 429 citations

Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the J_H locus

1993 • 404 citations

TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins.

1990 • 365 citations

Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations.

1991 • 355 citations

T helper type 1 development of naive CD4⁺ T cells requires the coordinate action of interleukin‐12 and interferon‐γ and is inhibited by transforming growth factor‐β

1994 • 288 citations

Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type.

1995 • 271 citations

Interleukin‐12/T cell stimulating factor, a cytokine with multiple effects on T helper type 1 (T_h1) but not on T_h2 cells

1993 • 241 citations

Normal Lymphocyte Development but Delayed Humoral Immune Response in CD81-null Mice

1997 • 231 citations

Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses.

1996 • 204 citations

Normal development but differentially altered proliferative responses of lymphocytes in mice lacking CD81

1997 • 196 citations

Polarization of IL-4- and IFN-gamma-producing CD4+ T cells following activation of naive CD4+ T cells.

1997 • 188 citations

Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice

1997 • 169 citations

B7–2 (CD86) is essential for the development of IL-4-producing T cells

1996 • 150 citations

Regulation of T helper cell cytokine expression: functional dichotomy of antigen‐presenting cells

1993 • 136 citations

Differential effects of interleukin‐12 on the development of naive mouse CD4⁺ T cells

1994 • 132 citations

TAPA-1, the Target of an Antiproliferative Antibody, Defines a New Family of Transmembrane Proteins

1990 • 132 citations

Antigen-specific B cells preferentially induce CD4+ T cells to produce IL-4.

1997 • 117 citations

B cells are required for the switch from Th1- to Th2-regulated immune responses to Plasmodium chabaudi chabaudi infection

1994 • 98 citations

In vivo activation of naive T cells by antigen-presenting B cells.

1994 • 95 citations

Polyclonal activation of the murine immune system by a goat antibody to mouse IgD. IX. Induction of a polyclonal IgE response.

1987 • 90 citations

Costimulation of IL-4 production by murine B7-1 and B7-2 molecules.

1996 • 79 citations

IL-4 synthesis by in vivo primed keyhole limpet hemocyanin-specific CD4+ T cells. I. Influence of antigen concentration and antigen-presenting cell type.

1992 • 69 citations

Role of antigen‐presenting cells in the polarized development of helper T cell subsets: evidence for differential cytokine production by Th0 cells in response to antigen presentation by B cells and macrophages

1994 • 66 citations

New CD from the B Cell Section of the Fifth International Workshop on Human Leukocyte Differentiation Antigens

1994 • 50 citations

Reconstitution of B-cell-depleted mice with B cells restores Th2-type immune responses during Plasmodium chabaudi chabaudi infection

1996 • 26 citations

Ligation of TAPA‐1 (CD81) or major histocompatibility complex class II in co‐cultures of human B and T lymphocytes enhances interleukin‐4 synthesis by antigen‐specific CD4⁺ T cells

1996 • 22 citations