Nod2 Mutation in Crohn's Disease Potentiates NF-κB Activity and IL-1ß Processing

Caspases: Enemies Within

1998 • 6,923 citations

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

2001 • 5,526 citations

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

2001 • 4,997 citations

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

1997 • 4,661 citations

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

2004 • 4,044 citations

Inflammatory Bowel Disease

2002 • 3,038 citations

IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

2004 • 2,361 citations

Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection

2003 • 2,325 citations

Infliximab Maintenance Therapy for Fistulizing Crohn's Disease

2004 • 2,133 citations

Inflammatory bowel disease: Etiology and pathogenesis

1998 • 2,095 citations

Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2

2003 • 1,651 citations

Nod2, a Nod1/Apaf-1 Family Member That Is Restricted to Monocytes and Activates NF-κB

2001 • 1,331 citations

The Immunology of Mucosal Models of Inflammation

2002 • 1,323 citations

Inflammatory Caspases

2004 • 917 citations

NOD2 is a negative regulator of Toll-like receptor 2–mediated T helper type 1 responses

2004 • 831 citations

Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B.

1998 • 721 citations

Recognition of microbial infection by Toll-like receptors

2003 • 556 citations

The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

2003 • 482 citations

The Induction of Apoptosis by Bacterial Pathogens

1999 • 409 citations

Different Subsets of Enteric Bacteria Induce and Perpetuate Experimental Colitis in Rats and Mice

2001 • 334 citations

Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

2003 • 260 citations

Priming of Macrophages with Lipopolysaccharide Potentiates P2X7-mediated Cell Death via a Caspase-1-dependent Mechanism, Independently of Cytokine Production

2002 • 191 citations

Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing

2003 • 160 citations