A semiautomated measure of whole-brain atrophy in multiple sclerosis

Axonal Transection in the Lesions of Multiple Sclerosis

1998 • 4,007 citations

Defining the clinical course of multiple sclerosis

1996 • 3,606 citations

Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS

1999 • 728 citations

Histopathologic correlate of hypointense lesions on T1-weighted spin-echo MRI in multiple sclerosis

1998 • 652 citations

Thalamic neurodegeneration in multiple sclerosis

2002 • 488 citations

Progressive cerebral atrophy in multiple sclerosis A serial MRI study

1996 • 482 citations

A longitudinal study of brain atrophy and cognitive disturbances in the early phase of relapsing-remitting multiple sclerosis

2001 • 378 citations

Eight-year follow-up study of brain atrophy in patients with MS

2002 • 376 citations

A longitudinal study of brain atrophy in relapsing multiple sclerosis

1999 • 334 citations

Patterns of lesion development in multiple sclerosis: longitudinal observations with T1-weighted spin-echo and magnetization transfer MR.

1998 • 266 citations

T2 Hypointensity in the Deep Gray Matter of Patients With Multiple Sclerosis

2002 • 233 citations

Brain MRI lesions and atrophy are related to depression in multiple sclerosis

2000 • 224 citations

Brain Atrophy in Relapsing-Remitting Multiple Sclerosis and Secondary Progressive Multiple Sclerosis: Longitudinal Quantitative Analysis

2000 • 219 citations

MRI in multiple sclerosis: correlation with expanded disability status scale (EDSS)

1999 • 202 citations

Fluid-Attenuated Inversion Recovery Magnetic Resonance Imaging Detects Cortical and Juxtacortical Multiple Sclerosis Lesions

2001 • 200 citations

Brain iron transport and neurodegeneration

2001 • 191 citations

Iron and oxygen radicals in brain

1992 • 186 citations

Detection of ventricular enlargement in patients at the earliest clinical stage of MS

2000 • 184 citations

Reduced signal intensity on MR images of thalamus and putamen in multiple sclerosis: increased iron content?

1987 • 182 citations

High‐Resolution Fluorodeoxyglucose Positron Emission Tomography Shows Both Global and Regional Cerebral Hypometabolism in Multiple Sclerosis

1998 • 169 citations

Bicaudate Ratio as a Magnetic Resonance Imaging Marker of Brain Atrophy in Multiple Sclerosis

2002 • 150 citations

A Wallerian degeneration pattern in patients at risk for MS

2000 • 139 citations

Quality of Life and Its Relationship to Brain Lesions and Atrophy on Magnetic Resonance Images in 60 Patients With Multiple Sclerosis

2000 • 136 citations

Whole brain volume changes in patients with progressive MS treated with cladribine

2000 • 123 citations

Brain atrophy in relapsing-remitting multiple sclerosis: relationship with ‘black holes’, disease duration and clinical disability

2000 • 122 citations

Frontal Cortex Atrophy Predicts Cognitive Impairment in Multiple Sclerosis

2002 • 119 citations

Brain magnetic resonance imaging correlates of cognitive impairment in multiple sclerosis

1993 • 111 citations

Gray matter T2 hypointensity is related to plaques and atrophy in the brains of multiple sclerosis patients

2001 • 109 citations

Intraventricular CSF pulsation artifact on fast fluid-attenuated inversion-recovery MR images: analysis of 100 consecutive normal studies.

2000 • 107 citations

MRI T2 shortening (‘black T2’) in multiple sclerosis

2000 • 93 citations

Regional Brain Atrophy Is Associated With Physical Disability in Multiple Sclerosis: Semiquantitative Magnetic Resonance Imaging and Relationship to Clinical Findings

2001 • 88 citations

The Correlation Between Ventricular Diameter Measured by Transcranial Sonography and Clinical Disability and Cognitive Dysfunction in Patients With Multiple Sclerosis

2000 • 86 citations

Ventricular enlargement in multiple sclerosis: a comparison of three-dimensional and linear MRI estimates

2001 • 63 citations

Enhancing Magnetic Resonance Imaging Lesions and Cerebral Atrophy in Patients With Relapsing Multiple Sclerosis

2001 • 51 citations

Frontal Cortex Atrophy Predicts Cognitive Impairment in Multiple Sclerosis

2002 • 48 citations

A longitudinal study of ventricular volume in early relapsing-remitting multiple sclerosis

2000 • 46 citations

Magnetic Resonance Imaging of Multiple Sclerosis

2002 • 36 citations

Is Gadolinium Enhancement Predictive of the Development of Brain Atrophy in Multiple Sclerosis? A Review of the Literature

2002 • 26 citations