Calmodulin mediates melatonin cytoskeletal effects

Calmodulin Plays a Pivotal Role in Cellular Regulation

1980 • 2,441 citations

Brain dopamine receptors.

1980 • 1,878 citations

ISOLATION OF MELATONIN, THE PINEAL GLAND FACTOR THAT LIGHTENS MELANOCYTES¹

1958 • 1,634 citations

Three-dimensional structure of calmodulin

1985 • 1,035 citations

Polarized monolayers formed by epithelial cells on a permeable and translucent support

1978 • 869 citations

Organization and function of a central nervous system circadian oscillator: the suprachiasmatic hypothalamic nucleus.

1983 • 689 citations

Binding of trifluoperazine to the calcium-dependent activator of cyclic nucleotide phosphodiesterase.

1977 • 544 citations

Effects of melatonin on vertebrate circadian systems

1990 • 414 citations

Hydrophobic regions function in calmodulin-enzyme(s) interactions.

1980 • 363 citations

The Fate of Melatonin in Animals

1961 • 341 citations

Occluding junctions and cytoskeletal components in a cultured transporting epithelium

1980 • 327 citations

On the effect of melatonin upon human brain. Its possible therapeutic implications

1971 • 320 citations

Melatonin. A Mammalian Pineal Hormone*

1981 • 284 citations

Calmodulin is required for cell-cycle progression during G1 and mitosis.

1989 • 248 citations

Specific Binding of Melatonin in Bovine Brain*

1979 • 218 citations

Binding of 3H-melatonin to calmodulin

1993 • 207 citations

Photoperiodism and Effects of Indoleamines in a Unicellular Alga, Gonyaulax polyedra

1991 • 156 citations

Concerted regulation of protein phosphorylation and dephosphorylation by calmodulin

1991 • 155 citations

Melatonin binding sites in the central nervous system

1991 • 155 citations

Role of Cyclic AMP in Mediating the Effects of MSH, Norepinephrine, and Melatonin on Frog Skin Color

1969 • 155 citations

THE UPTAKE OF H3-MELATONIN IN ENDOCRINE AND NERVOUS TISSUES AND THE EFFECTS OF CONSTANT LIGHT EXPOSURE.

1964 • 154 citations

Evidence for a cytoplasmic melatonin receptor

1978 • 153 citations

Melatonin: a principal neuroimmunoregulatory and anti-stress hormone: its anti-aging effects

1987 • 153 citations

Immunohistological localization of N-acetylindolealkylamines in pineal gland, retina and cerebellum

1974 • 151 citations

Calmodulin activates the isolated catalytic unit of brain adenylate cyclase.

1981 • 147 citations

Immunohistological localization of melatonin in the rat digestive system

1977 • 145 citations

Melatonin and the pineal gland: from basic science to clinical application

1992 • 145 citations

Regional Uptake of 3H-Melatonin from Blood or Cerebrospinal Fluid by Rat Brain

1969 • 135 citations

Melatonin receptors in brain

1979 • 126 citations

Mechanism of activation of cyclic nucleotide phosphodiesterase: requirement of the binding of four Ca2+ to calmodulin for activation.

1981 • 123 citations

Pigment aggregation by melatonin in the retinal pigment epithelium and choroid of guinea-pigs,Cavia porcellus

1979 • 120 citations

Hydrophobic interaction of the Ca2+-calmodulin complex with calmodulin antagonists. Naphthalenesulfonamide derivatives.

1982 • 113 citations

Nerve Fiber Growth and Its Regulation by Extrinsic Factors

1982 • 105 citations

Mitotic arrest by melatonin

1973 • 102 citations

Calmodulin and its role in intracellular calcium regulation

1987 • 100 citations

Melatonin modifies calmodulin cell levels in MDCK and N1E-115 cell lines and inhibits phosphodiesterase activity in vitro

1991 • 97 citations

Melatonin in seasonal affective disorder and phototherapy.

1986 • 93 citations

Neurotensin Stimulates Inositol Phospholipid Metabolism and Calcium Mobilization in Murine Neuroblastoma Clone N1E‐115

1986 • 89 citations

Intrinsic calcium sensitivity of tubulin polymerization. The contributions of temperature, tubulin concentration, and associated proteins.

1981 • 88 citations

Melatonin Receptors

1991 • 83 citations

Melatonin effects on brain. Interaction with microtubule protein, inhibition of fast axoplasmic flow and induction of crystaloid and tubular formations in the hypothalamus

1975 • 74 citations

FLUXES, JUNCTIONS, AND BLISTERS IN CULTURED MONOLAYERS OF EPITHELIOID CELLS (MDCK)*

1981 • 73 citations

Melatonin Effects on the Cytoskeletal Organization of MDCK and Neuroblastoma N1E‐115 Cells

1990 • 69 citations

Effects of melatonin treatment and environmental lighting on the ultrastructural appearance, melatonin synthesis, norepinephrine turnover and microtubule protein content of the rat pineal gland

1975 • 68 citations

Changes in the organization of the neuritic cytoskeleton during nerve growth factor-activated differentiation of PC12 cells: a serial electron microscopic study of the development and control of neurite shape.

1986 • 67 citations

Fate of Intracisternally Injected Melatonin in the Rat Brain

1973 • 66 citations

Neurohumoral Coding of Brain Function

1973 • 64 citations

THE ACTION OF MELATONIN ON SINGLE AMPHIBIAN PIGMENT CELLS IN TISSUE CULTURE

1977 • 47 citations

Regulation of mitosis: II. interaction of isopropyl N-phenyl-carbamate and melatonin

1969 • 46 citations

Calmodulin plays a dominant role in determining neurotransmitter regulation of neuronal adenylate cyclase

1988 • 44 citations

Regulation of cAMP concentration by calmodulin-dependent cyclic nucleotide phosphodiesterase

1986 • 38 citations

Melatonin: Inhibition of Microtubule‐Based Oral Morphogenesis in Stentor coeruleus

1972 • 37 citations

Clinical Study of Melatonin in Untreatable Advanced Cancer Patients

1987 • 36 citations

Melatonin antagonizes colchicine-induced mitotic arrest

1976 • 35 citations

The control of granule movement in fish melanophores

1985 • 31 citations

Structure-activity relationships of phenothiazines and related drugs for inhibition of protein kinase C.

1991 • 31 citations

The calmodulin-binding domain on microtubule-associated protein 2.

1984 • 30 citations

Is melatonin a microtubule inhibitor?

1976 • 27 citations

The effects of melatonin and epinephrine on the melanophores of freshwater teleosts

1969 • 27 citations

A comparative study of the interaction of chlorpromazine, trifluoperazine, and promethazine with mouse brain tubulin.

1981 • 25 citations

On the Mechanism of Calmodulin-Induced Inhibition of Microtubule Assembly In Vitro1

1986 • 21 citations

Melatonin: cellular effects on live stentors correlated with the inhibition of colchicine-binding to microtubule protein.

1974 • 21 citations

MICROTUBULES AND THE MOVEMENT OF MELANIN GRANULES IN FROG DERMAL MELANOCYTES*

1975 • 21 citations

The Influence of Certain Hormones and Chemicals on Mammalian Pigment Cells**From the Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.

1966 • 20 citations

Effects of Indole Alkaloids and Related Compounds on the Properties of Brain Microtubular Protein

1975 • 19 citations

Calcium and Calmodulin in the Regulation of the Microtubular Cytoskeletona

1986 • 19 citations

Intrinsic Calcium Sensitivity of Tubulin Polymerization

1981 • 18 citations

Effects of cold and melatonin on the microtubules of the toad sciatic nerve

1981 • 16 citations

Subneuronal Fate of Intracerebroventricular Injected ³H‐Melatonin

1988 • 16 citations

Characterization of [3H]Ro 5-4864 binding to calmodulin using a rapid filtration technique

1987 • 13 citations

Calmodulin modulation of adverse effects of Cd2+ on microtubules and tubulin polymerization in vitro

1989 • 12 citations

Synthesis and phosphorylation of cytoskeletal proteins during the in vitro biogenesis of MDCK cell monolayers

1989 • 9 citations

Modulation of Subcortical Inhibitory Mechanisms by Melatonin

1974 • 8 citations

Chemical Agents Effective in Mediating Control of Growth and Division Synchrony of Plasmodium berghei in Pinealectomized Mice

1969 • 7 citations

Melatonin binding to D2 receptors in rat striatum: a comparative study with calmodulin antagonists.

1991 • 4 citations