Preparation and characterization of guanidinated trypsinogen and iε-guanidinated trypsin

A Protein Sequenator

1967 • 2,826 citations

Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

1969 • 1,060 citations

p-Nitrophenyl-p′-guanidinobenzoate HCl: A new active site titrant for trypsin

1967 • 848 citations

The Use of Cyanate for the Determination of NH2-terminal Residues in Proteins

1963 • 472 citations

The Reaction of Imidoesters with Proteins and Related Small Molecules

1962 • 306 citations

Molecular structural effects produced in proteins by reaction with succinic anhydride

1958 • 269 citations

IDENTIFICATION OF A PEPTIDE RELEASED DURING AUTOCATALYTIC ACTIVATION OF TRYPSINOGEN

1955 • 236 citations

The amino acid sequence around the reactive serine residue of some proteolytic enzymes

1960 • 199 citations

ESSENTIAL GROUPS FOR THE INTERACTION OF OVOMUCOID (EGG WHITE TRYPSIN INHIBITOR) AND TRYPSIN, AND FOR TRYPTIC ACTIVITY

1949 • 191 citations

Effects of the Amidination Reaction on Antibody Activity and on the Physical Properties of Some Proteins^*

1963 • 181 citations

[1] Accelerated methods

1967 • 146 citations

Isolation of trypsins by affinity chromatography

1971 • 114 citations

The Preparation of Orthoesters

1942 • 105 citations

7 Chymotrypsin-Chemical Properties and Catalysis

1971 • 100 citations

6 The Structure of Chymotrypsin

1971 • 84 citations

Preparation of Chemically Defined ɛN‐Acetylated Trypsin

1967 • 82 citations

Amino acid sequence of thermolysin. Isolation and characterization of the fragments obtained by cleavage with cyanogen bromide

1972 • 75 citations

The Involvement of the Amino-terminal Amino Acid in the Activity of Pancreatic Proteases

1967 • 68 citations

Relation of the α-amino group of trypsin to enzyme function and zymogen activation

1973 • 64 citations

GUANIDINE COMPOUNDS. II. PREPARATION OF MONO- AND N,N-DI-ALKYLGUANIDINES

1958 • 63 citations

Sur la séquence N-terminale du trypsinogéne et son ablation pendant l'activation de ce zymogéne

1955 • 55 citations

STUDIES ON THE AUTOCATALYTIC ACTIVATION OF TRYPSINOGEN

1957 • 50 citations

A NEW REAGENT FOR THE GUANIDINATION OF PROTEINS

1960 • 42 citations

Activity and conformation of the alkaline form of δ-chymotrypsin studied by the specific acylation of isoleucine-16

1970 • 38 citations

TRYPSINOGEN-KINASE IN ASPERGILLUS ORYZAE

1959 • 27 citations

Chemical modifications of amino groups of trypsin

1969 • 15 citations

Tryptic cleavage of homoarginyl bonds in the oxidized guanidinated derivative of a bovine trypsin inhibitor (Kunitz inhibitor)

1971 • 6 citations