A Lipopolysaccharide- and β-1,3-Glucan-binding Protein from Hemocytes of the Freshwater Crayfish Pacifastacus leniusculus

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane

1971 • 8,619 citations

Phylogenetic Perspectives in Innate Immunity

1999 • 2,478 citations

Innate Immunity: The Virtues of a Nonclonal System of Recognition

1997 • 2,397 citations

The Instructive Role of Innate Immunity in the Acquired Immune Response

1996 • 1,731 citations

Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

1996 • 1,687 citations

Pathogenetic Mechanisms of Septic Shock

1993 • 1,577 citations

Integrins.

1991 • 1,369 citations

Role of the prophenoloxidase-activating system in invertebrate immunity

1998 • 1,292 citations

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1998 • 1,218 citations

Antimicrobial peptides in insects; structure and function

1999 • 1,001 citations

A peptidoglycan recognition protein in innate immunity conserved from insects to humans

1998 • 471 citations

Purification of a Peptidoglycan Recognition Protein from Hemolymph of the Silkworm, Bombyx mori

1996 • 466 citations

Penaeidins, a New Family of Antimicrobial Peptides Isolated from the Shrimp Penaeus vannamei (Decapoda)

1997 • 419 citations

Molecular immune responses of the mosquito Anopheles gambiae to bacteria and malaria parasites

1997 • 373 citations

Bacterial Endotoxins

1992 • 372 citations

Innate immunity in higher insects

1996 • 358 citations

New Types of Clotting Factors and Defense Molecules Found in Horseshoe Crab Hemolymph: Their Structures and Functions

1998 • 291 citations

Pro-phenol oxidase activating proteinase from an insect, Manduca sexta: A bacteria-inducible protein similar to Drosophila easter

1998 • 260 citations

The Expansion Rate and Size of the Universe

1992 • 248 citations

Hemolin: an Insect-Immune Protein Belonging to the Immunoglobulin Superfamily

1990 • 247 citations

cDNA cloning of prophenoloxidase from the freshwater crayfish Pacifastacus leniusculus and its activation.

1995 • 242 citations

C-type lectins and galectins mediate innate and adaptive immune functions: their roles in the complement activation pathway

1999 • 238 citations

Prophenoloxidase-activating Enzyme of the Silkworm, Bombyx mori

1999 • 229 citations

The crayfish plasma clotting protein: A vitellogenin-related protein responsible for clot formation in crustacean blood

1999 • 222 citations

Purification and molecular cloning of an inducible gram-negative bacteria-binding protein from the silkworm, Bombyx mori.

1996 • 209 citations

Purification and Characterization of a Proline‐Rich Antibacterial Peptide, with Sequence Similarity to Bactenecin‐7, from the Haemocytes of the Shore Crab, Carcinus Maenas

1996 • 197 citations

Studies on prophenoloxidase and protease activity of Blaberus craniifer haemocytes

1985 • 184 citations

Antimicrobial peptide, tachyplesin I, isolated from hemocytes of the horseshoe crab (Tachypleus tridentatus). NMR determination of the beta-sheet structure.

1990 • 182 citations

The lipopolysaccharide‐binding protein participating in hemocyte nodule formation in the silkworm Bombyx mori is a novel member of the C‐type lectin superfamily with two different tandem carbohydrate‐recognition domains¹

1999 • 180 citations

Limulus factor C. An endotoxin-sensitive serine protease zymogen with a mosaic structure of complement-like, epidermal growth factor-like, and lectin-like domains.

1991 • 177 citations

Crystal Structure of Hemolin: A Horseshoe Shape with Implications for Homophilic Adhesion

1998 • 177 citations

Identification and Cloning of a Glucan- and Lipopolysaccharide-binding Protein from Eisenia foetidaEarthworm Involved in the Activation of Prophenoloxidase Cascade

1998 • 176 citations

A Pattern Recognition Protein for Peptidoglycan

1999 • 172 citations

Purification and characterization of a beta-1,3-glucan binding protein from plasma of the crayfish Pacifastacus leniusculus.

1990 • 165 citations

Structure and biological activity of a 1,3-beta-D-glucan-binding protein in crustacean blood.

1994 • 150 citations

Purification of prophenoloxidase from crayfish blood cells, and its activation by an endogenous serine proteinase

1991 • 149 citations

The repair of wounds in the integument of insects

1966 • 149 citations

Isolation and characterization of immune-related genes from the fall webworm, Hyphantria cunea, using PCR-based differential display and subtractive cloning

1998 • 147 citations

The 76 kD cell-adhesion factor from crayfish haemocytes promotes encapsulation in vitro

1990 • 130 citations

Molecular mechanisms for mammalian melanogenesis

1991 • 122 citations

A cell-surface superoxide dismutase is a binding protein for peroxinectin, a cell-adhesive peroxidase in crayfish

1999 • 118 citations

Molecular cloning of cDNA for pro‐phenol‐oxidase‐activating factor I, a serine protease is induced by lipopolysaccharide or 1,3‐β‐glucan in coleopteran insect, Holotrichia diomphalia larvae

1998 • 117 citations

Function of the lipopolysaccharide‐binding protein of Periplaneta americana as an opsonin

1992 • 110 citations

Role of lectins in the innate immunity of horseshoe crab

1999 • 109 citations

Immune mechanisms in invertebrate vectors

1986 • 101 citations

Phagocytosis of Escherichia coli by Insect Hemocytes Requires Both Activation of the Ras/Mitogen-activated Protein Kinase Signal Transduction Pathway for Attachment and β3 Integrin for Internalization

1998 • 100 citations

A protein with protective properties against the cellular defense reactions in insects

1998 • 98 citations

Horseshoe crab (1,3)-beta-D-glucan-sensitive coagulation factor G. A serine protease zymogen heterodimer with similarities to beta-glucan-binding proteins.

1994 • 97 citations

Molecular cloning of cDNA for lipopolysaccharide-binding protein from the hemolymph of the American cockroach, Periplaneta americana. Similarity of the protein with animal lectins and its acute phase expression

1991 • 92 citations

Lipopolysaccharide‐Binding Proteins and their Involvement in the Bacterial Clearance from the Hemolymph of the Silkworm Bombyx Mori

1997 • 90 citations

Molecular cloning of the first metazoan beta-1,3 glucanase from eggs of the sea urchin Strongylocentrotus purpuratus.

1996 • 81 citations

Purification and partial characterization of a β‐1,3‐glucan‐binding‐protein membrane receptor from blood cells of the crayfish Pacifastacus leniusculus

1992 • 78 citations

Purified Horseshoe Crab Factor G

1995 • 77 citations

Structure of the data encoding β-1,3-glucanase A1 of Bacillus circulans WL-12

1990 • 76 citations

A Newly Identified Horseshoe Crab Lectin with Specificity for Blood Group A Antigen Recognizes Specific O-Antigens of Bacterial Lipopolysaccharides

1999 • 72 citations

The ?-1,3-glucan-binding protein from the crayfish Pacifastacus leniusculus, when reacted with a ?-1,3-glucan, induces spreading and degranulation of crayfish granular cells

1991 • 68 citations

Physiological aspects of the immunoglobulin superfamily in invertebrates

1999 • 54 citations

Molecular cloning and functional properties of two early‐stage encapsulation‐relating proteins from the coleopteran insect, Tenebrio molitor larvae

1999 • 38 citations

Molecular mechanisms for mammalian melanogenesis

1991 • 32 citations