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Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter

Data up to Jan 2025

Published1999
Citations135
References99

Total Citations Per Year

Abstract

References (99)

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY

1963 • 24,942 citations

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study.

1959 • 1,751 citations

Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin

1989 • 1,570 citations

The Fine Structure of the Nervous System: Neurons and Their Supporting Cells

1991 • 1,522 citations

The control of firing pattern in nigral dopamine neurons: burst firing

1984 • 1,326 citations

Ventral tegmental (A10) system: neurobiology. 1. Anatomy and connectivity

1987 • 1,003 citations

Discussion

1998 • 972 citations

Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area

1992 • 832 citations

Handbook of chemical neuroanatomy

2005 • 776 citations

Nicotine activates and desensitizes midbrain dopamine neurons

1997 • 762 citations

Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area

1994 • 741 citations

Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats

1986 • 693 citations

Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter

1991 • 587 citations

Nicotine maintains robust self-administration in rats on a limited-access schedule

1989 • 586 citations

The dopamine transporter: immunochemical characterization and localization in brain

1995 • 586 citations

Cloning and Expression of a Cocaine-Sensitive Dopamine Transporter Complementary DNA

1991 • 584 citations

Dopamine Axon Varicosities in the Prelimbic Division of the Rat Prefrontal Cortex Exhibit Sparse Immunoreactivity for the Dopamine Transporter

1998 • 578 citations

Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons

1985 • 527 citations

Systemic nicotine‐induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area

1994 • 524 citations

Optimization of differential immunogold-silver and peroxidase labeling with maintenance of ultrastructure in brain sections before plastic embedding

1990 • 450 citations

Vesicular acetylcholine transporter (VAChT) protein: A novel and unique marker for cholinergic neurons in the central and peripheral nervous systems

1997 • 409 citations

Nicotinic effects on the firing pattern of midbrain dopamine neurons

1986 • 399 citations

Electrophysiological Characterization of GABAergic Neurons in the Ventral Tegmental Area

1998 • 387 citations

Functional identification of a vesicular acetylcholine transporter and its expression from a “cholinergic” gene locus.

1994 • 383 citations

The pharmacology of mesolimbic dopamine neurons: a dual-probe microdialysis study in the ventral tegmental area and nucleus accumbens of the rat brain

1996 • 376 citations

Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area

1995 • 371 citations

Cloning and functional characterization of a cocaine‐sensitive dopamine transporter

1991 • 362 citations

Cholinergic Hyperactivity and Negative Schizophrenic Symptoms

1989 • 353 citations

Tonic Activation of NMDA Receptors Causes Spontaneous Burst Discharge of Rat Midbrain Dopamine Neurons In Vivo

1993 • 350 citations

Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system

1987 • 350 citations

Ascending projections from the pedunculopontine tegmental nucleus and the adjacent mesopontine tegmentum in the rat

1988 • 343 citations

GABA-containing neurons in the ventral tegmental area project to the nucleus accumbens in rat brain

1995 • 326 citations

Behavioural assessment of mice lacking D1A dopamine receptors

1998 • 325 citations

Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. I. Central nervous system

1998 • 324 citations

Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area

1992 • 315 citations

Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles.

1996 • 294 citations

Nicotinic excitation of rat ventral tegmental neurones in vitro studied by intracellular recording

1989 • 291 citations

Muscarinic cholinergic receptor subtypes in the human brain. II. Quantitative autoradiographic studies

1986 • 288 citations

Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles

1996 • 283 citations

Burst firing induced in midbrain dopamine neurons by stimulation of the medial prefrontal and anterior cingulate cortices

1988 • 281 citations

Preferential stimulation of ventral tegmental area dopaminergic neurons by nicotine

1987 • 275 citations

Localization of m5 muscarinic receptor mRNA in rat brain examined by in situ hybridization histochemistry

1990 • 268 citations

Dopamine transporter immunoreactivity in rat brain

1995 • 245 citations

The Dopamine Transporter: Comparative Ultrastructure of Dopaminergic Axons in Limbic and Motor Compartments of the Nucleus Accumbens

1997 • 240 citations

Neurohistochemistry, Modern Methods and Applications

1987 • 234 citations

Excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental area

1985 • 231 citations

Pedunculopontine nucleus in the squirrel monkey: Cholinergic and glutamatergic projections to the substantia nigra

1994 • 225 citations

N-methyl-d-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens

1997 • 211 citations

Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and laterodorsal tegmental nucleus-lesioned rats

1996 • 211 citations

Cholinergic input to dopaminergic neurons in the substantia nigra: A double immunocytochemical study

1991 • 210 citations

Infusion of Nicotine in the Ventral Tegmental Area or the Nucleus Accumbens of the Rat Differentially Affects Accumbal Dopamine Release

1994 • 204 citations

Subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mRNA for the dopamine transporter: Comparison with the mRNA for the D2 receptor, tyrosine hydroxylase and calbindin immunoreactivity

1995 • 195 citations

Role of Tegmental Cholinergic Neurons in Dopaminergic Activation, Antimuscarinic Psychosis and Schizophrenia

1995 • 192 citations

Molecular cloning of a putative vesicular transporter for acetylcholine.

1994 • 183 citations

Cholinergic projections to the substantia nigra from the pedunculopontine and laterodorsal tegmental nuclei

1989 • 171 citations

Cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus

1992 • 159 citations

Muscarine depolarizes rat substantia nigra zona compacta and ventral tegmental neurons in vitro through M1-like receptors.

1990 • 156 citations

Effects of local and repeated systemic administration of (−)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex

1995 • 154 citations

The pharmacology of mesocortical dopamine neurons: a dual-probe microdialysis study in the ventral tegmental area and prefrontal cortex of the rat brain.

1998 • 151 citations

Electrophysiological properties of mouse dopamine neurons: In vivo and in vitro studies

1984 • 149 citations

Ultrastructural localization of tyrosine hydroxylase in the rat ventral tegmental area: relationship between immunolabeling density and neuronal associations

1990 • 146 citations

Dopamine transporter mRNA: dense expression in ventral midbrain neurons

1992 • 140 citations

Both Nicotinic and Muscarinic Receptors in Ventral Tegmental Area Contribute to Brain-Stimulation Reward

1997 • 137 citations

Differential expression of tyrosine hydroxylase and membrane dopamine transporter genes in subpopulations of dopaminergic neurons of the rat mesencephalon

1994 • 135 citations

Excitatory Amino Acid Receptors in the Ventral Tegmental Area Regulate Dopamine Release in the Ventral Striatum

1996 • 130 citations

Non-NMDA excitatory amino acid receptors in the ventral tegmental area mediate systemic dizocilpine (MK-801) induced hyperlocomotion and dopamine release in the nucleus accumbens

1998 • 129 citations

GABA-labeled terminals form proportionally more synapses with dopaminergic neurons containing low densities of tyrosine hydroxylase-immunoreactivity in rat ventral tegmental area

1991 • 126 citations

Synaptic innervation of midbrain dopaminergic neurons by glutamate-enriched terminals in the squirrel monkey

1996 • 123 citations

Burst firing of mesencephalic dopamine neurons is inhibited by somatodendritic application of kynurenate

1991 • 122 citations

Dopamine transporter mRNA expression is intense in rat midbrain neurons and modest outside midbrain

1993 • 120 citations

Muscarinic cholinergic hyperactivity in schizophrenia

1991 • 116 citations

Immunogold Localization of the Dopamine Transporter: An Ultrastructural Study of the Rat Ventral Tegmental Area

1997 • 115 citations

The role of afferents to the ventral tegmental area in the handling stress-induced increase in the release of dopamine in the medial prefrontal cortex: a dual-probe microdialysis study in the rat brain

1998 • 109 citations

Distribution of the vesicular acetylcholine transporter (VAChT) in the central and peripheral nervous systems of the rat

1994 • 107 citations

Activation of midbrain presumed dopaminergic neurones by muscarinic cholinergic receptors: an in vivo electrophysiological study in the rat

1998 • 107 citations

Nicotine injections into the ventral tegmental area increase locomotion and Fos-like immunoreactivity in the nucleus accumbens of the rat

1996 • 103 citations

Distribution of choline acetyltransferase immunoreactive axons and terminals in the rat and ferret brainstem

1991 • 100 citations

Immunohistochemical localization of a neuronal nicotinic acetylcholine receptor in mammalian brain.

1987 • 99 citations

Ultrastructural localization of CART (cocaine- and amphetamine-regulated transcript) peptides in the nucleus accumbens of monkeys

1997 • 98 citations

The cholinergic innervation of the rat substantia nigra: a light and electron microscopic immunohistochemical study

1988 • 97 citations

Autoradiographic localization of dopamine uptake sites in the rat brain with3H-GBR 12935

1992 • 93 citations

Cholinergic neurons of the feline pontomesencephalon. II. Ascending anatomical projections

1990 • 92 citations

Immunohistochemical localization of the nicotinic acetylcholine receptor subunit α6 to dopaminergic neurons in the substantia nigra and ventral tegmental area

1997 • 90 citations

The dopamine transporter and dopamine D2 receptor messenger RNAs are differentially expressed in limbic- and motor-related subpopulations of human mesencephalic neurons

1994 • 87 citations

Modulation of cellular excitability in neocortex: Muscarinic receptor and second messenger‐mediated actions of acetylcholine

1994 • 80 citations

Monoclonal Antibodies Against Glutaraldehyde‐Conjugated Dopamine

1987 • 76 citations

Distribution of the putative vesicular transporter for acetylcholine in the rat central nervous system

1997 • 70 citations

Dopamine transporter immunohistochemistry in median eminence, amygdala, and other areas of the rat brain

1996 • 66 citations

Cholinergic somata and terminals in the rat substantia nigra: An immunocytochemical study with optical and electron microscopic techniques

1989 • 63 citations

Expression of Cytoplasmic and Nuclear Vasopressin RNA Following Castration and Testosterone Replacement: Evidence for Transcriptional Regulation

1994 • 58 citations

Cholinergic neurons in the rat substantia nigra

1986 • 48 citations

Nicotinic potentiation of glutamatergic synapses in the prefrontal cortex: New insight into the analysis of the role of nicotinic receptors in cognitive functions

1994 • 44 citations

Presynaptic nicotinic acetylcholine receptors in the brain

1996 • 40 citations

Differential distribution of the putative vesicular transporter for acetylcholine in the rat central nervous system

1996 • 31 citations

Recent biochemical studies of the dopamine transporter — A CNS drug target

1998 • 29 citations

5-Fluoronicotine, noranhydroecgonine, and pyridyl-methylpyrrolidine release acetylcholine and biogenic amines in rat cortex in vivo

1995 • 20 citations

Activation of nigral M1 and M2 muscarinic receptors produces opposing effects on striatal 3,4-dihydroxyphenylacetic acid measured by in vivo voltammetry

1991 • 14 citations

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Cholinergic axon terminals in the ventral tegmental area target a subpopulation of… (1999) – The Journal of Comparative Neurology | Metascience Observatory Explorer