Myocardial dysfunction and ultrastructural alterations mediated by oxygen metabolites

Biology of disease: free radicals and tissue injury.

1982 • 3,078 citations

The catalytic decomposition of hydrogen peroxide by iron salts

1934 • 2,483 citations

Handbook of methods for oxygen radical research

1987 • 2,395 citations

Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts

1986 • 2,052 citations

Quantitative Aspects of the Production of Superoxide Anion Radical by Milk Xanthine Oxidase

1970 • 1,037 citations

The importance of free radicals and catalytic metal ions in human diseases

1985 • 939 citations

Superoxide‐dependent formation of hydroxyl radicals in the presence of iron chelates

1978 • 748 citations

Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine

1979 • 637 citations

Role of oxygen in the cellular damage induced by re-oxygenation of hypoxic heart

1980 • 550 citations

Molecular oxygen: Friend and foe*The role of the oxygen free radical system in the calcium paradox, the oxygen paradox and ischemia/reperfusion injury

1984 • 543 citations

Mechanisms of lipid peroxidation

1985 • 542 citations

The role of lipid peroxidation in pathogenesis of ischemic damage and the antioxidant protection of the heart

1982 • 523 citations

Superoxide and superoxide dismutases

1993 • 518 citations

Reperfusion-induced arrhythmias and oxygen-derived free radicals. Studies with "anti-free radical" interventions and a free radical-generating system in the isolated perfused rat heart.

1986 • 396 citations

Adenosine-5′-triphosphate

1965 • 313 citations

Oxygen, ischemia and inflammation.

1986 • 313 citations

Myocardial alterations due to free-radical generation

1984 • 308 citations

Role of oxygen radicals in cardiac injury due to reoxygenation*

1984 • 276 citations

Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals

1979 • 268 citations

Increase in microvascular permeability induced by enzymatically generated free radicals

1981 • 237 citations

The independent effects of oxygen radical scavengers on canine infarct size. Reduction by superoxide dismutase but not catalase.

1985 • 234 citations

Mechanisms of the killing of cultured hepatocytes by hydrogen peroxide

1984 • 172 citations

Involvement of hydrogen peroxide and hydroxyl radical in the ‘oxygen paradox’: Reduction of creatine kinase release by catalase, allopurinol or deferoxamine, but not by superoxide dismutase**

1985 • 168 citations

Reactions of ferrioxamine and desferrioxamine with the hydroxyl radical

1982 • 151 citations

Evidence that ischemic cell death begins in the subendocardium independent of variations in collateral flow or wall tension.

1983 • 110 citations

Superoxide dismutase enhances recovery following myocardial ischemia

1985 • 98 citations

Influence of oxygen radicals generated by xanthine oxidase in the isolated perfused rat heart

1986 • 90 citations

Influence of exogenously generated oxidant species on myocardial function

1986 • 90 citations

Free radical mediation of the effects of acidosis on calcium transport by cardiac sarcoplasmic reticulum in whole heart homogenates

1984 • 89 citations

Iron mobilization from ferritin by chelating agents

1980 • 89 citations

The degradation of cytochrome c by hydrogen peroxide

1985 • 78 citations

O2 free radical-mediated myocardial and vascular dysfunction

1986 • 74 citations

A new peroxidase color reaction: Oxidative coupling of 3-methyl-2-benzothiazolinone hydrazone (MBTH) with its formaldehyde azine. Application to glucose and choline oxidases

1983 • 72 citations

Effects of free radical generation on mouse pial arterioles: probable role of hydroxyl radicals

1983 • 66 citations

Lipid peroxidation as a mechanism of injury in cardiac myocytes.

1982 • 62 citations

Ultrastructural changes induced in the isolated rat heart by enzymatically generated oxygen radicals

1987 • 59 citations

Free oxygen radicals in cerebral vascular responses.

1983 • 49 citations

Isolated Heart Preparations Perfused or Superfused with Balanced Salt Solutions

1984 • 32 citations

Oxygen derived radicals related injury in the heart during calcium paradox

1987 • 12 citations