Subgroups of the BENEFIT study: Risk of developing MS and treatment effect of interferon beta-1b

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis

1993 • 2,032 citations

Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis

1993 • 1,908 citations

Intramuscular Interferon Beta-1A Therapy Initiated during a First Demyelinating Event in Multiple Sclerosis

2000 • 1,497 citations

A Randomized, Controlled Trial of Corticosteroids in the Treatment of Acute Optic Neuritis

1992 • 1,254 citations

Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis

1997 • 1,246 citations

Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group.

1993 • 1,227 citations

Early clinical predictors and progression of irreversible disability in multiple sclerosis: an amnesic process

2003 • 963 citations

Placebo-controlled multicentre randomised trial of interferon β-1b in treatment of secondary progressive multiple sclerosis

1998 • 931 citations

Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes

2006 • 660 citations

Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes

2006 • 552 citations

MRI T2 lesion burden in multiple sclerosis

2006 • 205 citations

Optic neuritis

1998 • 194 citations

Effect of interferon-?1b on magnetic resonance imaging outcomes in secondary progressive multiple sclerosis: Results of a European multicenter, randomized, double-blind, placebo-controlled trial

1999 • 158 citations

Validation of diagnostic magnetic resonance imaging criteria for multiple sclerosis and response to interferon β1a

2003 • 136 citations

Interferon β‐1a for early multiple sclerosis: CHAMPS trial subgroup analyses

2002 • 133 citations

MRI criteria for dissemination in space in patients with clinically isolated syndromes: a multicentre follow-up study

2006 • 130 citations

Is optic neuritis more benign than other first attacks in multiple sclerosis?

2005 • 128 citations

Isolated demyelinating syndromes: comparison of CSF oligoclonal bands and different MR imaging criteria to predict conversion to CDMS

2001 • 113 citations

Predictors of relapse rate in MS clinical trials

2005 • 81 citations

The effects of intramuscular interferon beta-Ia in patients at high risk for development of multiple sclerosis: A post hoc analysis of data from CHAMPS

2003 • 48 citations

Discrepancies in the interpretation of clinical symptoms and signs in the diagnosis of multiple sclerosis. A proposal for standardization

2005 • 36 citations

Predictors of short-term disease activity following a first clinical demyelinating event: analysis of the CHAMPS placebo groupy

2002 • 11 citations