The impact of obesity, fat distribution, and energy restriction on insulin-like growth factor-1 (IGF-1), IGF-binding protein-3, insulin, and growth hormone

Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity

1987 • 1,218 citations

Total and visceral adipose-tissue volumes derived from measurements with computed tomography in adult men and women: predictive equations.

1988 • 791 citations

Impaired growth hormone secretion in the adult population: relation to age and adiposity.

1981 • 643 citations

Williams Textbook of Endocrinology

1992 • 574 citations

Short-Term Metabolic Effects of Recombinant Human Insulin-like Growth Factor I in Healthy Adults

1987 • 554 citations

A novel technique for the determination of body fat by computed tomography.

1983 • 508 citations

Dual Defects in Pulsatile Growth Hormone Secretion and Clearance Subserve the Hyposomatotropism of Obesity in Man*

1991 • 481 citations

A Specific Radioimmunoassay for the Growth Hormone (GH)-Dependent Somatomedin-Binding Protein: Its Use for Diagnosis of GH Deficiency

1990 • 460 citations

Adiposity, Fat Distribution, and Cardiovascular Risk

1989 • 430 citations

Wick Chromatography for Rapid and Reliable Immunoassay of Insulin, Glucagon and Growth Hormone

1968 • 400 citations

Adipose tissue volume determinations in women by computed tomography: technical considerations.

1986 • 331 citations

Insulin-like growth factors and insulin: comparative aspects

1985 • 262 citations

Endocrine function in human obesity

1981 • 234 citations

Treatment of Obese, Diet-Restricted Subjects with Growth Hormone for 11 Weeks: Effects on Anabolism, Lipolysis, and Body Composition*

1988 • 185 citations

The distal axis of growth hormone (GH) in nutritional disorders: GH-binding protein, insulin-like growth factor-I (IGF-I), and IGF-I receptors in obesity and anorexia nervosa

1992 • 179 citations

The relationship between insulin-like growth factor-I, adiposity, and aging

1990 • 156 citations

REDUCED GROWTH HORMONE RESPONSE TO GROWTH HORMONE‐RELEASING HORMONE IN CHILDREN WITH SIMPLE OBESITY: EVIDENCE FOR SOMATOMEDIN‐C MEDIATED INHIBITION

1987 • 149 citations

Growth Hormone Administration Conserves Lean Body Mass during Dietary Restriction in Obese Subjects*

1987 • 144 citations

7 Somatomedin activity in disorders of nutrition and metabolism

1984 • 128 citations

Kidney tissue somatomedin C and initial renal growth in diabetic and uninephrectomised rats

1988 • 128 citations

Increased upper body and overall adiposity is associated with decreased sex hormone binding globulin in postmenopausal women.

1991 • 122 citations

Endocrine Aspects of Obesity

1989 • 121 citations

Recombinant human insulin-like growth factor I (rhIGF I) reduces hyperglycaemia in patients with extreme insulin resistance

1991 • 115 citations

Use of Insulin-Like Growth Factor-Binding Protein 3 for the Evaluation of Growth Disorders

1990 • 104 citations

Short-Term Changes in Serum Insulin-Like Growth Factors (IGF) and IGF Binding Protein 3 after Different Modes of Intravenous Growth Hormone (GH) Exposure in GH-Deficient Patients

1991 • 102 citations

Intra-abdominal fat is associated with decreased insulin sensitivity in healthy young men

1991 • 98 citations

Increased parathyroid hormone as a consequence of changed complex binding of plasma calcium in morbid obesity

1986 • 70 citations

DECREASED SEX HORMONE BINDING GLOBULIN (SHBG) AND INSULIN‐LIKE GROWTH FACTOR BINDING PROTEIN (IGFBP‐1) IN EXTREME OBESITY

1990 • 69 citations

Integrated concentrations of growth hormone, insulin, C-peptide and prolactin in human obesity

1982 • 65 citations

92195928 Increased upper body and overall adiposity is associated with decreased sex hormone binding globulin in postmenopausal women

1992 • 59 citations

Insulin-Like Growth Factor-I as a Reflection of Body Composition, Nutrition, and Puberty in Sixth and Seventh Grade Girls*

1991 • 58 citations

Inter‐relations between growth hormone, insulin, insulin‐like growth factor‐l (IGF‐I), IGF‐binding protein‐1 (IGFBP‐1) and sex hormone‐binding globulin in acromegaly

1991 • 57 citations

Evidence against growth hormone-releasing factor deficiency in children with idiopathic obesity

1986 • 53 citations

Spontaneous growth hormone and somatomedin-C/insulin-like growth factor-l secretion in obese subjects during puberty

1988 • 50 citations

Circadian patterns of serum insulin-like growth factor (IGF) II and IGF binding protein 3 in growth hormone-deficient patients and age- and sex-matched normal subjects

1990 • 49 citations

Regional Body Fat Measurements with CT‐scan and Evaluation of Anthropometric Predictions

1987 • 49 citations

GROWTH HORMONE RESPONSE TO LOW DOSE INTRAVENOUS INJECTIONS OF GROWTH HORMONE RELEASING FACTOR IN OBESE AND NORMAL WEIGHT WOMEN

1986 • 45 citations

ALTERED HYPOTHALAMIC AND SYMPATHETIC RESPONSES TO HYPOGLYCAEMIA IN FAMILIAL OBESITY

1982 • 44 citations

RELATIONS BETWEEN IMMUNOREACTIVE SOMATOMEDIN C, INSULIN AND T3 PATTERNS DURING FASTING IN OBESE SUBJECTS

1984 • 44 citations

Study of Insulin-Like Growth Factor I in Human Obesity

1991 • 40 citations

The effect of synthetic very low calorie diets on the GH-IGF-1 axis in obese subjects

1990 • 29 citations

Effect of obesity on plasma insulin-like growth factor-I in cancer patients.

1991 • 23 citations

Regional Obesity and Serum Lipids in European Women Born in 1948

1987 • 23 citations

Insulin-like growth factor-I in non-insulin-dependent diabetic monkeys: Basal plasma concentrations and metabolic effects of exogenously administered biosynthetic hormone

1991 • 20 citations

Formula diet plus free additional food choice up to 1000 kcal (4.2 MJ) compared with an isoenergetic conventional diet in the treatment of obesity. A randomised clinical trial

1987 • 18 citations

Reduction of plasma insulin levels does not restore integrated concentration of growth hormone to normal in obese children.

1992 • 15 citations

Serum Somatomedin Activity and Growth Hormone Level in Obese Men: Dependence on Degree of Obesity and Hyperlipidemia

2009 • 13 citations

Effect of obesity on plasma insulin-like growth factor-I in cancer patients.

1991 • 10 citations

Single sc Administration of Insulin-Like Growth Factor I (IGF-I) in Normal Men

1991 • 7 citations