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The Mechanism of Paracetamol-induced Hepatotoxicity: Implications for Therapy

Data up to Jan 2025

Published1983
Citations12
References16

Total Citations Per Year

Abstract

References (16)

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism.

1973 • 1,467 citations

Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo.

1973 • 1,174 citations

Acetaminophen-induced Hepatic Necrosis

1974 • 1,021 citations

PLASMA-PARACETAMOL HALF-LIFE AND HEPATIC NECROSIS IN PATIENTS WITH PARACETAMOL OVERDOSAGE

1971 • 610 citations

LIVER NECROSIS FROM PARACETAMOL

1966 • 304 citations

Acetaminophen hepatotoxicity

1980 • 108 citations

Quantitative determination of the glutathione, cysteine, and N-acetyl cysteine conjugates of acetaminophen by high-pressure liquid chromatography

1977 • 87 citations

Treatment of acetaminophen poisoning. The use of oral methionine

1981 • 76 citations

Treatment of Severe Acetaminophen Poisoning With Intravenous Acetylcysteine

1981 • 72 citations

Treatment of Acetaminophen Poisoning

1981 • 66 citations

Paracetamol oxidation: synthesis and reactivity of N-acetyl-p-benzoquinoneimine

1980 • 55 citations

Studies on the effects of l-ascorbic acid on acetaminophen-induced hepatotoxicity

1981 • 43 citations

Late presentation of acetaminophen hepatotoxicity

1982 • 28 citations

Rapid micro-method for the measurement of paracetamol in blood plasma or serum using gas-liquid chromatography with flame-ionisation detection

1981 • 23 citations

Chromatographic Analysis of Synthetic N-Acetyl-p-Benzoquinoneimine: The Putative Reactive Metabolite of Paracetamol

1983 • 7 citations

Detoxification of the putative reactive metabolite of paracetamol with glutathione

1982 • 5 citations

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The Mechanism of Paracetamol-induced Hepatotoxicity: Implications for Therapy (1983) – Human Toxicology | Metascience Observatory Explorer