Tetradecanoyl phorbol-13-acetate counteracts the responsiveness of cultured thyroid cells to thyrotropin

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.

1984 • 715 citations

In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: Part 1

1980 • 477 citations

Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells.

1982 • 417 citations

Tumour promotor induces plasminogen activator

1976 • 316 citations

Adenosine 3′,5′ cyclic monophosphate assay at 10−15 mole level

1973 • 262 citations

Evidence for two sources of arachidonic acid for oxidative metabolism by mouse peritoneal macrophages.

1982 • 247 citations

Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Putative effect of C kinase on alpha s-GTP-catalytic subunit interaction.

1985 • 239 citations

Chromatography of phosphatides on silicic acid impregnated paper

1956 • 217 citations

Effects of phorbol-12,13-diesters on prostaglandin production and phospholipase activity in canine kidney (MDCK) cells

1977 • 155 citations

Polarity of three-dimensional structures derived from isolated hog thyroid cells in primary culture

1979 • 138 citations

Enzyme translocation in the regulation of phosphatidylcholine biosynthesis

1984 • 134 citations

The phorbol ester, TPA inhibits glucagon‐stimulated adenylate cyclase activity

1984 • 128 citations

Regulation of rat liver cytosolic CTP: phosphocholine cytidylyltransferase by phosphorylation and dephosphorylation.

1982 • 109 citations

Tumor promoter stimulation of phosphatidylcholine turnover in HeLa cells.

1982 • 98 citations

Modulation of Adenylate Cyclase/Cyclic AMP Response by Thyrotropin and Prostaglandin E2 in Cultured Thyroid Cells. 1. Negative Regulation

1978 • 86 citations

Effects of 12-o-tetradecanoylphorbol 13-acetate on glycerolipid metabolism in cultured myoblasts

1982 • 80 citations

Forskolin Stimulation of Thyroid Adenylate Cyclase and Cyclic 3′,5′-Adenosine Monophosphate Accumulation

1982 • 78 citations

Forskolin requires more than the catalytic unit to activate adenylate cyclase

1982 • 70 citations

Tetradecanoyl-phorbol acetate stimulates phosphatidylcholine biosynthesis in hela cells by an increase in the rate of the reaction catalyzed by CTP: Phosphocholine cytidylyltransferase

1980 • 70 citations

Genetic evidence that a phorbol ester tumor promoter stimulates ornithine decarboxylase activity by a pathway that is independent of cyclic AMP‐dependent protein kinases in CHO cells

1982 • 56 citations

Stimulation by forskolin of the thyroid adenylate cyclase, cyclic amp accumulation and iodine metabolism

1983 • 54 citations

Alterations of glial tumor cell Ca2+ metabolism and Ca2+-dependent cAMP accumulation by phorbol myristate acetate.

1982 • 53 citations

Alterations in lipid metabolism induced by 12-O-tetradecanoylphorbol-13-acetate in differentiating human myeloid leukemia cells.

1980 • 52 citations

Membrane Phospholipid Turnover, Receptor Function and Protein Phosphorylation

1982 • 49 citations

Rapid alteration in Ca++ content and fluxes in phorbol 12-myristate 13-acetate treated myoblasts

1980 • 47 citations

Enhancement by 3-isobutyl-1-methylxanthine and cholera toxin of 12-O-tetradecanoylphorbol-13-acetate-stimulated cyclic nucleotide levels and ornithine decarboxylase activity in isolated epidermal cells.

1980 • 46 citations

Modulation of Adenylate Cyclase/Cyclic AMP Response by Thyrotropin and Prostaglandin E2 in Cultured Thyroid Cells. 2. Positive Regulation

1978 • 45 citations

Modulation of phagocytosis by tumor promoters and epidermal growth factor in normal and transformed macrophages.

1980 • 43 citations

Chronic and acute effects of thyrotropin on phosphatidylinositol turnover in cultured porcine thyroid cells

1982 • 30 citations

A tumor‐promoting phorbol ester inhibits the cyclic AMP response of rat embryo fibroblasts to catecholamines and prostaglandin E₁

1979 • 30 citations

Calcium‐dependent release of arachidonic acid from a murine epidermal cell line induced by the tumor promoter TPA or ionophore a 23187

1982 • 29 citations

Involvement of calcium, calmodulin and phospholipase A in the alteration of membrane dynamics and superoxide production of human neutrophils stimulated by phorbol myristate acetate

1982 • 28 citations

Phorbol ester tumor promoters specifically stimulate choline phospholipid metabolism in human leukemic cells

1984 • 26 citations

Effects of chlorpromazine, propranolol and phospholipase C on thyrotropin and prostaglandin stimulation of adenyl cyclase-cyclic AMP system in dog thyroid slices

1970 • 24 citations

Induction of plasminogen activator by 12-O-tetradecanoylphorbol-13-acetate and calcium ionophore

1983 • 24 citations

Enhancement of hormone action by a phorbol ester and anti-tubulin alkaloids involves different mechanisms

1982 • 22 citations

Structure of the thyrotropin receptor and thyroid adenylate cyclase system as determined by target analysis

1984 • 18 citations

Persistent activity modification of phosphatidate phosphohydrolase and fatty acyl‐CoA synthetase on incubation of adipocytes with the tumour promoter 12‐O‐tetradecanoylphorbol 13‐acetate

1985 • 17 citations

Interaction de la thyreostimuline avec ses recepteurs cellulaires: Effet de la phospholipase C sur la fixation et l'activité biologique

1971 • 16 citations

Forskolin stimulates adenylate cyclase and idodine metabolism in thyroid

1982 • 16 citations

Relationship between the “phospholipid effect” and calcium in the thyroid

1979 • 15 citations

Regulation of phosphatidylcholine synthesis and the activity of CTP:cholinephosphate cytidylyltransferase in myoblasts by 12-O-tetradecanoylphorbol-13-acetate

1984 • 13 citations

Alteration of cyclic nucleotide levels in phorbol 12-myristate 13-acetate treated myoblasts

1980 • 13 citations

Effects of arachidonate on cultured pig thyroid cells and their stimulation by thyrotropin

1981 • 12 citations

Effects of eicosatetraynoic acid (ETYA) on cultured pig thyroid cells

1982 • 6 citations