GABAA receptor subunit expression changes in the rat cerebellum and cerebral cortex during aging

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon

1992 • 1,525 citations

Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology

1989 • 1,283 citations

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum

1992 • 673 citations

Cerebellar GABAA receptor selective for a behavioural alcohol antagonist

1990 • 536 citations

Two novel GABAA receptor subunits exist in distinct neuronal subpopulations

1989 • 532 citations

Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site.

1990 • 415 citations

GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs.

1989 • 404 citations

Comparative molecular neuroanatomy of cloned GABA_Areceptor subunits in the rat CNS

1992 • 382 citations

A novel α subunit in rat brain GABAA receptors

1989 • 251 citations

Neuron numbers and sizes in aging brain: Comparisons of human, monkey, and rodent data

1988 • 243 citations

Subcellular localization of benzodiazepine/GABAA receptors in the cerebellum of rat, cat, and monkey using monoclonal antibodies

1989 • 234 citations

GABAA receptors display association of γ2-subunit with α1- and β2/3-subunits

1991 • 218 citations

Chronic ethanol administration alters gamma-aminobutyric acidA receptor gene expression.

1992 • 200 citations

Generation of Two Forms of the γ‐Aminobutyric Acid_A Receptor γ‐₂‐Subunit in Mice by Alternative Splicing

1991 • 196 citations

GABAA receptor subtypes immunopurified from rat brain with α subunit-specific antibodies have unique pharmacological properties

1991 • 195 citations

Chronic Ethanol Intoxication Induces Differential Effects on GABA_A and NMDA Receptor Function in the Rat Brain

1993 • 187 citations

Distribution and plasticity of immunocytochemically localized GABAA receptors in adult monkey visual cortex

1990 • 181 citations

GABAA receptor populations with novel subunit combinations and drug binding profiles identified in brain by alpha 5- and delta-subunit-specific immunopurification.

1993 • 170 citations

Prolonged ethanol inhalation decreases gamma-aminobutyric acidA receptor alpha subunit mRNAs in the rat cerebral cortex.

1991 • 169 citations

Localization of the GABAA receptor in the rat brain with a monoclonal antibody to the 57,000 Mr peptide of the GABAA receptor/benzodiazepine receptor/Cl- channel complex

1988 • 165 citations

Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. II. Chronic effects of ethanol.

1990 • 163 citations

GABAA receptor subunit immunoreactivity in primate visual cortex: distribution in macaques and humans and regulation by visual input in adulthood

1994 • 137 citations

Model of subunit composition of gamma-aminobutyric acid A receptor subtypes expressed in rat cerebellum with respect to their alpha and gamma/delta subunits.

1994 • 118 citations

Monoclonal antibodies and conventional antisera to the GABAA receptor/benzodiazepine receptor/Cl- channel complex

1988 • 118 citations

Chronic ethanol treatment upregulates the GABA receptor β subunit expression

1994 • 102 citations

Age-related decrease of GABAA receptor subunits and glutamic acid decarboxylase in the rat inferior colliculus

1994 • 98 citations

Immunocytochemical localization of gamma 2 short and gamma 2 long subunits of the GABAA receptor in the rat brain

1994 • 94 citations

Characterisation of δ-subunit containing GABAA receptors from rat brain

1995 • 94 citations

The Subunit Composition of a GABA_A/Benzodiazepine Receptor from Rat Cerebellum

1994 • 89 citations

The α₁ and α₆ Subunits Can Coexist in the Same Cerebellar GABA_A Receptor Maintaining Their Individual Benzodiazepine‐Binding Specificities

1996 • 81 citations

A prominent epitope on GABAA receptors is recognized by two different monoclonal antibodies

1992 • 80 citations

Mapping of GABAA receptor α5 and α6 subunit-like immunoreactivity in rat brain

1992 • 76 citations

Quantitative Characterization of α6 and α1α6 Subunit-containing Native γ-Aminobutyric AcidA Receptors of Adult Rat Cerebellum Demonstrates Two α Subunits per Receptor Oligomer

1995 • 69 citations

Short and Long Form γ₂ Subunits of the GABA_A/Benzodiazepine Receptors

1994 • 63 citations

Differential localization of type I and type II benzodiazepine binding sites in substantia nigra

1983 • 61 citations

Aging related alterations in GABAA receptor subunit mRNA levels in Fischer rats

1992 • 51 citations

Immunocytochemical localization of the ?6 subunit of the ?-aminobutyric acidA receptor in the rat nervous system

1996 • 51 citations

Antibodies to the Human γ₂ Subunit of the γ‐Aminobutyric Acid_A/Benzodiazepine Receptor

1993 • 47 citations

Enhancement of GABA-activated membrane currents in aged Fischer 344 rat basal forebrain neurons [published erratum appears in J Neurosci 1995 Jul;15(7):following table of contents]

1995 • 47 citations

Aging reduces the GABA-dependent 36Cl− flux in rat brain membrane vesicles

1988 • 45 citations

Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.

1991 • 41 citations

Binding characteristics of 3H-flunitrazepam and CL-218,872 in cerebellum and cortex of C57B1 mice made tolerant to and dependent on phenobarbital or ethanol

1985 • 40 citations

Differential expression of the short and long forms of the γ2 subunit of the GABAA/benzodiazepine receptors

1994 • 39 citations

Solubilization of Brain Benzodiazepine Receptors with a Zwitterionic Detergent: Optimal Preservation of Their Functional Interaction with the GABA Receptors

1983 • 39 citations

Aging-related subunit expression changes of the GABAA receptor in the rat hippocampus

1996 • 38 citations

Differential Expression of GABA_A/Benzodiazepine Receptor Subunit mRNAs and Ligand Binding Sites in Mouse Cerebellar Neurons Following In Vivo Ethanol Administration: An Autoradiographic Analysis

1995 • 35 citations

Effects of chronic ethanol inhalation on the enhancement of benzodiazepine binding to mouse brain membranes by GABA

1987 • 31 citations

Age‐Related Loss of t‐[³⁵S]Butylbicyclophosphorothionate Binding to the γ‐Aminobutyric Acid_A Receptor‐Coupled Chloride Ionophore in Rat Cerebral Cortex

1989 • 31 citations

Aging‐Associated Changes in the Pharmacological Properties of the Benzodiazepine (ω) Receptor Isotypes in the Rat Hippocampus

1995 • 31 citations

Altered expression of γ2L and γ2S GABAA receptor subunits in the aging rat brain

1996 • 30 citations

Molecular characterization of Type I GABAA receptor complex from rat cerebral cortex and hippocampus

1994 • 28 citations

Effects of chronic ethanol administration on [3H]zolpidem binding in rat brain

1994 • 27 citations

Aging reduces the mRNA of α1 GABAA receptor subunit in rat cerebral cortex

1991 • 24 citations

Molecular heterogeneity of the type I GABAA/benzodiazepine receptor complex

1994 • 24 citations

Age-dependent regulation of GABAA receptors in neocortex

1992 • 21 citations

Modification of γ‐Aminobutyric Acid_A Receptor Binding and Function by N‐Ethoxycarbonyl‐2‐Ethoxy‐1,2‐Dihydroquinoline In Vitro and In Vivo: Effects of Aging

1991 • 21 citations

Absence of modifications of the pharmacological properties of the GABAA receptor complex during aging, as assessed in 3- and 24-month-old rat cerebral cortex

1993 • 20 citations

Levels of Benzodiazepine Receptor Subtypes and GABA_A Receptor α‐Subunit mRNA Do Not Correlate During Development

1994 • 17 citations

Dutch science: Ministry plans intervention

1983 • 2 citations

Deleted Work

1955 • 0 citations