The role of cytochromes P-450 in adrenal steroidogenesis

Isolation from adrenal cortex of a nonheme iron protein and a flavoprotein functional as a reduced triphosphopyridine nucleotide-cytochrome P-450 reductase

1966 • 379 citations

Microsomal cytochrome P-450 from neonatal pig testis: two enzymic activities (17.alpha.-hydroxalase and C17,20 associated with one protein

1981 • 291 citations

Phenobarbital-induced rat liver cytochrome P-450. Purification and characterization of two closely related isozymic forms.

1982 • 221 citations

Immunochemical Studies on Electron Transport Chains Involving Cytochrome P-450

1971 • 211 citations

Studies on the steroid hydroxylation system in adrenal cortex microsomes. Purification and characterization of cytochrome P-450 specific for steroid C-21 hydroxylation.

1980 • 171 citations

Ionic effects on adrenal steroidogenic electron transport. The role of adrenodoxin as an electron shuttle.

1979 • 167 citations

Flavins and flavoproteins 1987

1989 • 141 citations

Purification and immunochemical characterization of the two adrenal cortex mitochondrial cytochrome P-450-proteins

1978 • 136 citations

Properties of an adrenal cytochrome P-450 (P-45011) for the hydroxylations of corticosteroids

1978 • 122 citations

Aldosterone synthesis by adrenal mitochondria

1967 • 109 citations

Phosphatidylcholine vesicle reconstituted cytochrome P-450scc. Role of the membrane in control of activity and spin state of the cytochrome.

1980 • 94 citations

Purification and some properties of cytochrome P-450 specific for steroid 17α-hydroxylation and C17C20 bond cleavage from guinea pig adrenal microsomes

1982 • 92 citations

Are polyphosphoinositides the cycloheximide-sensitive mediator in the steroidogenic actions of adrenocorticotropin and adenosine-3‘,5‘-monophosphate?

1980 • 89 citations

Cytochrome P-450scc. Cardiolipin as an effector of activity of a mitochondrial cytochrome P-450.

1981 • 86 citations

Purification and properties of 17α-hydroxylase from microsomes of pig adrenal: A scond C21side-chain cleavage system

1983 • 76 citations

Steroid 21-hydroxylase (cytochrome P-450) from porcine adrenocortical microsomes: microsequence analysis of cysteine-containing peptides

1983 • 59 citations

Purification and reconstitution of the steroid 21-hydroxylase system (cytochrome P-450-linked mixed function oxidase system) of bovine adrenocortical microsomes.

1981 • 54 citations

Purification and reconstitution of the steroid 21-hydroxylase system (cytochrome P-450-linked mixed function oxidase system) of bovine adrenocortical microsomes

1981 • 45 citations

19-Hydroxylation of 18-hydroxy-11-deoxycorticosterone catalyzed by cytochrome P-45011 beta of bovine adrenocortex.

1983 • 43 citations

Biochemistry of Steroid Hormones

1976 • 43 citations

Structural features of isozyme 2 of liver microsomal cytochrome P-450. Identification of a highly conserved cysteine-containing peptide.

1982 • 35 citations

In vitro synthesis of mitochondrial cytochromes P-450(scc) and P-450(11-β) and microsomal cytochrome P-450(C-21) by both free and bound polysomes isolated from bovine adrenal cortex

1980 • 33 citations

The final step of aldosterone biosynthesis is catalyzed by an NADPH-dependent and molecular oxygen-requiring enzyme

1982 • 20 citations

The final step of aldosterone biosynthesis requires reducing power

1983 • 14 citations

Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex.

1983 • 13 citations

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