Progression of carcinogen‐induced foci of y‐glutamyltranspeptidase‐positive hepatocytes to hepatomas in rats fed a choline‐deficient diet

HISTOCHEMICAL AND ULTRASTRUCTURAL DEMONSTRATION OF γ-GLUTAMYL TRANSPEPTIDASE ACTIVITY

1969 • 940 citations

Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis.

1977 • 541 citations

The stages of initiation and promotion in hepatocarcinogenesis

1980 • 515 citations

Biochemical characterisation of stages of hepatocarcinogenesis after a single dose of diethylnitrosamine

1978 • 415 citations

Quantitative evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcinogenesis from diethylnitrosamine.

1980 • 374 citations

Report of a workshop on classification of specific hepatocellular lesions in rats.

1975 • 371 citations

Early histological and functional alterations of ethionine liver carcinogenesis in rats fed a choline-deficient diet.

1978 • 248 citations

Regression and persistence of hyperplastic hepatic nodules induced by N-2-Fluorenylacetamide and their relationship to hepatocarcinogenesis.

1971 • 221 citations

Oral contraceptive steroids as promoters of hepatocarcinogenesis in female Sprague-Dawley rats.

1980 • 206 citations

Phenotypic diversity as an early property of putative preneoplastic hepatocyte populations in liver carcinogenesis.

1980 • 203 citations

Effects of varying the exposure to phenobarbital on its enhancement of 2-acetylaminofluorene-induced hepatic tumorigenesis in the rat.

1973 • 193 citations

Histochemistry of Gamma-Glutamyl Transpeptidase in Rat Liver During Aflatoxin B1-Induced Carcinogenesis2

1975 • 181 citations

Quantitative histochemical and autoradiographic studies of hepatocarcinogenesis in rats fed 2-acetylaminofluorene followed by phenobarbital.

1978 • 157 citations

The Occurrence of Neoplasms in the Liver, Lungs, and Other Tissues of Rats as a Result of Prolonged Choline Deficiency.

1946 • 150 citations

Kinetics of induction and growth of enzyme-deficient islands involved in hepatocarcinogenesis.

1976 • 129 citations

Development of Preneoplastic and Neoplastic Lesions of the Liver in Male Rats Given 0.025 Percent <italic>N</italic>-2-Fluorenyldiacetamide<xref ref-type="fn" rid="FN2">2</xref>

1965 • 128 citations

Quantitative Kinetics of Development of N-2-Fluorenylacetamide-Induced, Altered (Hyperplastic) Hepatocellular Foci Resistant to Iron Accumulation and of Their Reversion or Persistence Following Removal of Carcinogen23

1978 • 118 citations

Growth kinetics of diethylnitrosamine-induced, enzyme-deficient "preneoplastic" liver cell populations in vivo and in vitro.

1972 • 111 citations

Enhancement of Rat Hepatocellular-Altered Foci by the Liver Tumor Promoter Phenobarbital: Evidence That Foci Are Precursors of Neoplasms and That the Promoter Acts on Carcinogen-Induced Lesions23

1978 • 107 citations

The effects of various chemicals on the development of hyperplastic liver nodules in hepatectomized rats treated with N-nitrosodiethylamine or N-2-fluorenylacetamide.

1980 • 103 citations

Effects of varying the dietary concentration of phenobarbital on its enhancement of 2-acetylaminofluorene-induced hepatic tumorigenesis.

1980 • 97 citations

Dietary effects on chemical carcinogenesis in animal models for colon and liver tumors.

1975 • 85 citations

Nutrition and experimental carcinogenesis: a review.

1975 • 81 citations

Induction of foci of altered, γ-glutamyltranspeptidase-positive hepatocytes in carcinogen-treated rats fed a choline-deficient diet

1979 • 81 citations

Enhancing effect of phenobarbital on the development of enzyme-altered islands and hepatocellular carcinomas initiated by 3'-methyl-4-(dimethylamino) azobenzene or diethylnitrosamine.

1978 • 77 citations

Enhancement of 2‐acetylaminofluorene liver carcinogenesis in rats fed a choline‐devoid diet

1979 • 72 citations

Histochemical analysis of hyperplastic lesions and hepatomas of the liver of rats fed 2-fluorenylacetamide.

1971 • 72 citations

Diet and aflatoxin B1 toxicity in rats

1971 • 68 citations

Variable effects of a lipotrope-deficient, high-fat diet on chemical carcinogenesis in rats.

1975 • 65 citations

Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the rat.

1979 • 64 citations

Effects of a choline-devoid diet on the emergence of gamma-glutamyltranspeptidase-positive foci in the liver of carcinogen-treated rats.

1979 • 63 citations

Synergistic effect of a choline-devoid diet and phenobarbital in promoting the emergence of foci of gamma-glutamyltranspeptidase-positive hepatocytes in the liver of carcinogen-treated rats.

1980 • 61 citations

A sequential quantitative study of the reversibility or irreversibility of liver hyperplastic nodules in rats exposed to hepatocarcinogens.

1980 • 51 citations

Azaserine carcinogenesis: Organ susceptibility change in rats fed a diet devoid of choline

1978 • 45 citations