Involvement of the Carboxyl-terminal Region of the α1 Subunit in Voltage-dependent Inactivation of Cardiac Calcium Channels

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation

1990 • 1,528 citations

Structural parts involved in activation and inactivation of the sodium channel

1989 • 1,189 citations

Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells

1994 • 998 citations

Calcium channel β-subunit binds to a conserved motif in the I–II cytoplasmic linker of the α1-subunit

1994 • 659 citations

Destruction of Sodium Conductance Inactivation in Squid Axons Perfused with Pronase

1973 • 540 citations

Molecular Basis for CA2+ Channel Diversity

1994 • 461 citations

Expression vector system based on the chicken β-actin promoter directs efficient production of interleukin-5

1989 • 431 citations

Acceleration of activation and inactivation by the β subunit of the skeletal muscle calcium channel

1991 • 291 citations

Gating of inwardly rectifying K+ channels localized to a single negatively charged residue

1994 • 253 citations

Amino acid residues required for fast Na(+)-channel inactivation: charge neutralizations and deletions in the III-IV linker.

1992 • 241 citations

Molecular determinants of voltage-dependent inactivation in calcium channels

1994 • 217 citations

Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit.

1994 • 192 citations

Differential phosphorylation of two size forms of the neuronal class C L-type calcium channel alpha 1 subunit.

1993 • 168 citations

Gating of Na channels. Inactivation modifiers discriminate among models.

1987 • 150 citations

Repeat I of the dihydropyridine receptor is critical in determining calcium channel activation kinetics

1991 • 145 citations

Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart.

1993 • 132 citations

Sodium channel activation in the squid giant axon. Steady state properties.

1985 • 114 citations

Critical roles of the S3 segment and S3-S4 linker of repeat I in activation of L-type calcium channels.

1994 • 114 citations

Cyclic AMP‐dependent phosphorylation and regulation of the cardiac dihydropyridine‐sensitive Ca channel

1992 • 109 citations

Voltage-dependent facilitation of a neuronal alpha 1C L-type calcium channel.

1994 • 106 citations

Function of a truncated dihydropyridine receptor as both voltage sensor and calcium channel

1992 • 93 citations

On the edge of a wing

1990 • 81 citations

Probability assessment of conformational ensembles: sugar repuckering in a DNA duplex in solution

1995 • 72 citations

Modification of L‐type calcium current by intracellularly applied trypsin in guinea‐pig ventricular myocytes.

1988 • 63 citations

Double-pulse facilitation of smooth muscle alpha 1-subunit Ca2+ channels expressed in CHO cells.

1994 • 54 citations

Cloning, chromosomal location and functional expression of the human voltage‐dependent calcium‐channel β3 subunit

1994 • 49 citations

Structural Characterization of the Dihydropyridine Receptor-Linked Calcium Channel from Porcine Heart1

1992 • 33 citations

Calcium currents in the A7r5 smooth muscle-derived cell line. Increase in current and selective removal of voltage-dependent inactivation by intracellular trypsin.

1991 • 26 citations

The beta subunit controls the gating and dihydropyridine sensitivity of the skeletal muscle Ca2+ channel

1992 • 25 citations

Subunit structure and phosphorylation of the cardiac L-type calcium channel

1994 • 9 citations