The covalent binding of polycyclic hydrocarbons to DNA in the skin of mice of different strains

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

An Improved Diphenylamine Method for the Estimation of Deoxyribonucleic Acid

1965 • 1,968 citations

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

1974 • 1,144 citations

An Improved Preparation of Sodium Desoxyribonucleate

1952 • 937 citations

Evidence for the Binding of Polynuclear Aromatic Hydrocarbons to the Nucleic Acids of Mouse Skin : Relation between Carcinogenic Power of Hydrocarbons and their Binding to Deoxyribonucleic Acid

1964 • 687 citations

Benzo[ a ]pyrene Diol Epoxides as Intermediates in Nucleic Acid Binding in Vitro and in Vivo

1976 • 584 citations

A New, Quantitative, Approach to the Study of the Stages of Chemical Carcinogenesis in the Mouse's Skin

1947 • 532 citations

Evaluation of six short term tests for detecting organic chemical carcinogens and recommendations for their use

1976 • 276 citations

Fluorescence spectral evidence that benzo(a)pyrene‐DNA products in mouse skin arise from diol‐epoxides

1975 • 198 citations

Isolation of the hydrocarbon-deoxyribonucleoside products from the DNA of mouse embryo cells treated in culture with 7-methylbenz(a)anthracene-3H.

1973 • 181 citations

Nucleoside adducts from the in vitro reaction of benzo[a]pyrene-7,8-dihydrodiol 9,10-oxide or benzo[a]pyrene 4,5-oxide with nucleic acids

1977 • 169 citations

Studies on the formation of protein-bound derivatives of 3,4-benzpyrene in the epidermal fraction of mouse skin.

1951 • 165 citations

Benzo[a]pyrene diol epoxide covalently binds to deoxyguanosine and deoxyadenosine in DNA

1977 • 146 citations

Molecular Geometry and Carcinogenic Activity of Aromatic Compounds. New Perspectives

1969 • 137 citations

The reaction of (±)‐7α, 8β‐dihydroxy‐9β, 10β‐epoxy‐7,8,9,10‐tetrahydrobenzo(a)pyrene with dna

1976 • 126 citations

The involvement of a diol‐epoxide in the metabolic activation of benzo(a)pyrene in human bronchial mucosa and in mouse skin

1976 • 125 citations

The interaction of 7,12-dimethylbenz(a)anthracene with cells sensitive and resistant to toxicity induced by this carcinogen.

1967 • 121 citations

Binding of tritium-labeled polycyclic hydrocarbons to DNA of mouse skin.

1967 • 118 citations

The interaction of carcinogenic hydrocarbons with tissue constituents. IV. A quantitative study of the binding to skin proteins of several C14-labeled hydrocarbons.

1956 • 116 citations

Metabolic activation of the carcinogen 7,12-dimethylbenz[a]anthracene for DNA binding

1977 • 101 citations

Relationships Between Aryl Hydrocarbon Hydroxylase Inducibility and Sensitivity to Chemically Induced Subcutaneous Sarcomas in Various Strains of Mice23

1973 • 99 citations

The role of aryl hydrocarbon hydroxylase in 7,12-dimethylbenz(a)anthracene skin tumorigenesis: on the mechanism of 7,8-benzoflavone inhibition of tumorigenesis.

1972 • 87 citations

The metabolic activation of 7-methylbenz(a)anthracene in mouse skin

1977 • 75 citations

Fluorescence spectral studies on the metabolic activation of 3‐methylcholanthrene and 7,12‐dimethylbenz[a]anthracene in mouse skin

1977 • 70 citations

Aryl hydrocarbon hydroxylase, epoxide hydrase, and 7,12-dimethylbenz(a)anthracene-produced skin tumorigenesis in the mouse.

1972 • 67 citations

Tumorigenicity of five dihydrodiols of benz(a)anthracene on mouse skin: exceptional activity of benz(a)anthracene 3,4-dihydrodiol.

1977 • 66 citations

Metabolic formation of 1,9,10-trihydroxy-9,10-dihydro-3-methylcholanthrene: a potential proximate carcinogen from 3-methylcholanthrene

1978 • 60 citations

Genetic differences in aryl hydrocarbon hydroxylase induction and benzo(a)pyrene-produced tumorigenesis in the mouse.

1973 • 59 citations

The metabolic activation of 7-methylbenz(a)anthracene in mouse skin: High tumour-initiating activity of the 3,4-dihydrodiol

1977 • 55 citations

The metabolism and dna binding of 3‐methyl‐cholanthrene

1977 • 45 citations

A study of skin carcinogenesis in the mouse with single applications of 9,10-dimethyl-1,2-benzanthracene at different dosages.

1960 • 39 citations

Photosensitivity of dna‐bound 7,12‐dimethylbenz(a)‐anthracene

1977 • 38 citations

Age-Related Modification of 7,12-Dimethylbenz[ a ]anthracene Binding to Rat Mammary Gland DNA 2

1978 • 37 citations

Metabolic activation of polycyclic hydrocarbons Fluorescence spectral evidence is consistent with metabolism at the 1,2‐ and 3,4‐double bonds of 7‐methylbenz[a]anthracene

1977 • 37 citations

Rapid separation of nucleosides and nucleotides by cation-exchange column chromatography

1969 • 31 citations

In vitro reaction of radioactive 7β,8α,-dihydroxy-9α, 10α-epoxy-7,8,9,10-tetrahydrobenzo(A)pyrene and 7β,8α-dihydroxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzo(A)pyrene with DNA

1977 • 29 citations

Genetic Differences in Benzo[a]pyrene Carcinogenic Index in Vivo and in Mouse Cytochrome P1 450-Mediated Benzo[a]pyrene Metabolite Binding to DNA in Vitro

1977 • 15 citations

Some properties of vicinal diol-epoxides derived from benz(a)anthracene and benzo(a)pyrene

1978 • 12 citations