Piperonyl Butoxide Metabolism by Cytochrome P-450: Factors Affecting the Formation and Disappearance of the Metabolite-Cytochrome P-450 Complex

A new spectral intermediate associated with cytochrome P-450 function in liver microsomes

1971 • 240 citations

On the inhibitory action of mersalyl on microsomal drug oxidation: A rigid organization of the electron transport chain

1971 • 188 citations

The Enzymic Formation of a Methylenedioxyphenyl Derivative Exhibiting an Isocyanide-like Spectrum with Reduced Cytochrome P-450 in Hepatic Microsomes

1971 • 134 citations

Methylene-C ¹⁴ -Dioxyphenyl Compounds: Metabolism in Relation to Their Synergistic Action

1966 • 121 citations

A cytochrome P-450-piperonyl butoxide spectrum similar to that produced by ethyl isocyanide

1971 • 108 citations

Inhibition of microsomal drug metabolism by methylenedioxybenzenes

1968 • 101 citations

Importance of demethylenation in the metabolism in vivo and in vitro of methylenedioxyphenyl synergists and related compounds in mammals

1970 • 94 citations

The production and modification of cytochrome P-450 difference spectra by in vivo administration of methylenedioxyphenyl compounds

1972 • 89 citations

Factors affecting the enzymatic formation of o-methylated dihydroxy derivatives

1965 • 74 citations

Use of homolytic, steric, and hydrophobic constants in a structure-activity study of 1,3-benzodioxole synergists

1968 • 66 citations

The relationship between microsomal epoxidation and lipid peroxidation in houseflies and pig liver and the inhibitory effect of derivatives of 1,3-benzodioxole (methylenedioxybenzene)

1967 • 65 citations

Properties of housefly microsomal cytochromes in relation to sex, strain, substrate specificity, and apparent inhibition and induction by synergist and insecticide chemicals

1970 • 59 citations

Insecticide synergist interactions with cytochrome P-450 in mouse liver microsomes

1970 • 48 citations

Induction of a new hepatic microsomal haemoprotein by safrole and isosafrole

1971 • 42 citations

The kinetics of inhibition of drug metabolism in vitro by some naturally occurring compounds

1970 • 22 citations

Interaction of safrole and isosafrole with hepatic microsomal haemoproteins

1972 • 21 citations

Paradoxical effects of piperonyl butoxide on the kinetics of mouse liver microsomal enzyme activity

1972 • 19 citations