Unfolding of Titin Domains Explains the Viscoelastic Behavior of Skeletal Myofibrils

Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFM

1997 • 2,985 citations

Stretching DNA

1995 • 2,148 citations

Folding-Unfolding Transitions in Single Titin Molecules Characterized with Laser Tweezers

1997 • 1,198 citations

Titins: Giant Proteins in Charge of Muscle Ultrastructure and Elasticity

1995 • 1,195 citations

Mechanical and chemical unfolding of a single protein: A comparison

1999 • 1,022 citations

The molecular elasticity of the extracellular matrix protein tenascin

1998 • 835 citations

Mechanical unfolding intermediates in titin modules

1999 • 796 citations

Elasticity and unfolding of single molecules of the giant muscle protein titin

1997 • 735 citations

The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line.

1988 • 608 citations

Elastically Coupled Two-Level Systems as a Model for Biopolymer Extensibility

1998 • 481 citations

Series of Exon-Skipping Events in the Elastic Spring Region of Titin as the Structural Basis for Myofibrillar Elastic Diversity

2000 • 367 citations

The study of protein mechanics with the atomic force microscope

1999 • 325 citations

Muscle assembly: a titanic achievement?

1999 • 323 citations

Regulation of skeletal muscle stiffness and elasticity by titin isoforms: a test of the segmental extension model of resting tension.

1991 • 314 citations

The Mechanical Stability of Immunoglobulin and Fibronectin III Domains in the Muscle Protein Titin Measured by Atomic Force Microscopy

1998 • 309 citations

Evidence for cross-bridge attachment in relaxed muscle at low ionic strength.

1982 • 300 citations

Immunoglobulin-like modules from titin I-band: extensible components of muscle elasticity

1996 • 298 citations

Reversible unfolding of fibronectin type III and immunoglobulin domains provides the structural basis for stretch and elasticity of titin and fibronectin.

1994 • 294 citations

Towards a Molecular Understanding of the Elasticity of Titin

1996 • 284 citations

Viscoelasticity of the sarcomere matrix of skeletal muscles. The titin-myosin composite filament is a dual-stage molecular spring

1993 • 251 citations

Nature of PEVK-titin elasticity in skeletal muscle

1998 • 246 citations

Connectin/titin, giant elastic protein of muscle

1997 • 240 citations

I-Band Titin in Cardiac Muscle Is a Three-Element Molecular Spring and Is Critical for Maintaining Thin Filament Structure

1999 • 237 citations

Titin Extensibility In Situ: Entropic Elasticity of Permanently Folded and Permanently Unfolded Molecular Segments

1998 • 237 citations

Actin-titin interaction in cardiac myofibrils: probing a physiological role

1997 • 171 citations

Mechanically Driven Contour-Length Adjustment in Rat Cardiac Titin’s Unique N2B Sequence

1999 • 165 citations

Titin/connectin and nebulin: Giant protein rulers of muscle structure and function

1996 • 158 citations

A comparison of the folding kinetics and thermodynamics of two homologous fibronectin type III modules

1997 • 123 citations

Characterizing titin’s I-band Ig domain region as an entropic spring

1998 • 119 citations

Titin: a molecular control freak

1999 • 115 citations

Titin elasticity and mechanism of passive force development in rat cardiac myocytes probed by thin-filament extraction

1997 • 113 citations

A molecular map of titin/connectin elasticity reveals two different mechanisms acting in series

1996 • 112 citations

A Spring Tale: New Facts on Titin Elasticity

1998 • 97 citations

Basis of passive tension and stiffness in isolated rabbit myofibrils

1997 • 92 citations

Temperature‐dependent changes in the viscoelasticity of intact resting mammalian (rat) fast‐ and slow‐twitch muscle fibres

1998 • 78 citations

PEVK Extension of Human Soleus Muscle Titin Revealed by Immunolabeling with the Anti-titin Antibody 9D10

1998 • 75 citations

Rapid refolding of a proline-rich all-beta-sheet fibronectin type III module.

1996 • 71 citations

Titin folding energy and elasticity

1993 • 69 citations

A Survey of the Primary Structure and the Interspecies Conservation of I-Band Titin's Elastic Elements in Vertebrates

1998 • 53 citations

Assembly of the cardiac I-band region of titin/connectin: expression of the cardiac-specific regions and their structural relation to the elastic segments

1996 • 38 citations

Tension relaxation after stretch in resting mammalian muscle fibers: stretch activation at physiological temperatures

1996 • 25 citations

Evidence That the Tandem Ig Domains near the End of the Muscle Thick Filament Form an Inelastic Part of the I-Band Titin

1997 • 24 citations

Viscoelasticity and function of connectin/ titin filaments in skinned muscle fibers

1996 • 11 citations

Viscoelasticity and function of connectin/ titin filaments in skinned muscle fibers

1996 • 10 citations

Titin elasticity Interaction and extensibility of PEVK segment of human fetal skeletal titin

1997 • 1 citations