Effects of modafinil on working memory processes in humans

Aviat space environ med

1992 • 7,493 citations

Role of locus coeruleus in attention and behavioral flexibility

1999 • 867 citations

Regional and cellular fractionation of working memory

1996 • 821 citations

Maintenance versus Manipulation of Information Held in Working Memory: An Event-Related fMRI Study

1999 • 782 citations

Memory in the Cerebral Cortex

1996 • 776 citations

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Catecholamine modulation of prefrontal cortical cognitive function

1998 • 596 citations

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2003 • 526 citations

Cognitive enhancing effects of modafinil in healthy volunteers

2003 • 514 citations

Attention and arousal, cognition and performance

1982 • 509 citations

Hypothalamic Arousal Regions Are Activated during Modafinil-Induced Wakefulness

2000 • 484 citations

Efficacy and safety of modafinil (Provigil(R)) for the treatment of fatigue in multiple sclerosis: a two centre phase 2 study

2002 • 455 citations

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2002 • 422 citations

Chemical neuromodulation of frontal-executive functions in humans and other animals

2000 • 400 citations

Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine

2001 • 397 citations

Randomized trial of modafinil as a treatment for the excessive daytime somnolence of narcolepsy

2000 • 359 citations

Functional neuroanatomical double dissociation of mnemonic and executive control processes contributing to working memory performance

1999 • 344 citations

D1- Versus D2-Receptor Modulation of Visuospatial Working Memory in Humans

1998 • 328 citations

Effects of Dextroamphetamine on Cognitive Performance and Cortical Activation

2000 • 299 citations

Modafinil improves cognition and response inhibition in adult attention-deficit/hyperactivity disorder

2004 • 296 citations

Modafinil for the Treatment of Daytime Sleepiness in Parkinson´s Disease: A Double-blind, Randomized, Crossover, Placebo-controlled Polygraphic Trial

2002 • 248 citations

An evaluation of the abuse potential of modafinil using methylphenidate as a reference

2000 • 238 citations

Improved short-term spatial memory but impaired reversal learning following the dopamine D2 agonist bromocriptine in human volunteers

2001 • 232 citations

Central α1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil; studies with experimental animals

1990 • 221 citations

Systemic sulpiride in young adult volunteers simulates the profile of cognitive deficits in Parkinson's disease

1999 • 220 citations

Role of catecholamines in the modafinil and amphetamine induced wakefulness, a comparative pharmacological study in the cat

1992 • 207 citations

Using executive heterogeneity to explore the nature of working memory deficits in Parkinson’s disease

2003 • 198 citations

Modafinil, d‐amphetamine and placebo during 64 hours of sustained mental work. I. Effects on mood, fatigue, cognitive performance and body temperature

1995 • 192 citations

Adjunct Modafinil for the Short-Term Treatment of Fatigue and Sleepiness in Patients With Major Depressive Disorder

2003 • 190 citations

Guanfacine, But Not Clonidine, Improves Planning and Working Memory Performance in Humans

1999 • 184 citations

Efficacy of Modafinil Compared to Dextroamphetamine for the Treatment of Attention Deficit Hyperactivity Disorder in Adults

2000 • 182 citations

A double-blind, placebo-controlled investigation of the efficacy of modafinil for sustaining the alertness and performance of aviators: a helicopter simulator study

2000 • 168 citations

Maintenance and Manipulation in Spatial Working Memory: Dissociations in the Prefrontal Cortex

2002 • 163 citations

A Double‐Blind, Placebo‐Controlled, Ascending‐Dose Evaluation of the Pharmacokinetics and Tolerability of Modafinil Tablets in Healthy Male Volunteers

1999 • 158 citations

The Vigilance Promoting Drug Modafinil Increases Extracellular Glutamate Levels in the Medial Preoptic Area and the Posterior Hypothalamus of the Conscious Rat Prevention by Local GABAA Receptor Blockade

1999 • 149 citations

Contrasting effects of clonidine and diazepam on tests of working memory and planning

1995 • 124 citations

Modafinil affects mood, but not cognitive function, in healthy young volunteers

2002 • 117 citations

Open‐Label, Single‐Dose Pharmacokinetic Study of Modafinil Tablets: Influence of Age and Gender in Normal Subjects

1999 • 116 citations

Self‐monitoring cognitive performance during sleep deprivation: effects of modafinil, d‐amphetamine and placebo

1997 • 114 citations

Effects of Modafinil in Children With Attention-Deficit/Hyperactivity Disorder: An Open-Label Study

2001 • 114 citations

The pharmacology of human working memory

2001 • 94 citations

Reduction in excess daytime sleepiness by modafinil in patients with myotonic dystrophy

2003 • 90 citations

Models of Functional Organization of the Lateral Prefrontal Cortex in Verbal Working Memory: Evidence in Favor of the Process Model

2002 • 90 citations

Neurochemical Modulation of Prefrontal Cortical Function in Humans and Animals

2002 • 83 citations

Effect of modafinil on fatigue, mood, and health-related quality of life in patients with narcolepsy

2004 • 80 citations

The hypocretin/orexin system in health and disease

2003 • 76 citations

Subdissociative Dose Ketamine Produces a Deficit in Manipulation but not Maintenance of the Contents of Working Memory

2003 • 74 citations

Homology in behavioural pharmacology: an approach to animal models of human cognition

1998 • 65 citations

First evidence of a delay-dependent working memory-enhancing effect of modafinil in mice

2001 • 60 citations

Functional magnetic resonance imaging neuroactivation studies in normal subjects and subjects with the narcoleptic syndrome. Actions of modafinil

1999 • 56 citations

Modafinil

1998 • 51 citations

Manipulation of working memory information is impaired in Parkinson's disease and related to working memory capacity.

2002 • 50 citations

Noradrenergic blockade and numeric working memory in humans

2005 • 43 citations

Disrupted Sleep-Wake Rhythm and Performance: Advantages of Modafinil

1995 • 42 citations

Modafinil During 64 Hr of Sleep Deprivation: Dose-Related Effects on Fatigue, Alertness, and Cognitive Performance

1998 • 38 citations

Effects of modafinil on attentional processes during 60 hours of sleep deprivation

1998 • 35 citations

High-performance liquid chromatographic determination of modafinil and its two metabolites in human plasma using solid-phase extraction

1998 • 34 citations

Effects of pallidal deep brain stimulation and levodopa treatment on reaction-time performance in Parkinson’s disease

2002 • 32 citations

Differential Demands on Working Memory for Guiding a Simple Action Sequence: Evidence from Closed-head-injured Subjects

2000 • 29 citations

Antagonism by modafinil of the psychomotor and cognitive impairment induced by sleep-deprivation in 12 healthy volunteers

1991 • 28 citations

Modafinil--medical considerations for use in sustained operations.

2003 • 26 citations

Initiating treatment with modafinil for control of excessive daytime sleepiness in patients switching from methylphenidate: an open-label safety study assessing three strategies

2003 • 21 citations

Manipulation of working memory information is impaired in Parkinson's disease and related to working memory capacity.

2002 • 20 citations