Thromboxane A2 Mediates Augmented Polymorphonuclear Leukocyte Adhesiveness

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

1975 • 3,075 citations

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin.

1978 • 1,559 citations

Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

1974 • 1,004 citations

The effects of bacterial endotoxins on host mediation systems. A review.

1978 • 648 citations

Inhibition of Granulocyte Adherence by Ethanol, Prednisone, and Aspirin, Measured with an Assay System

1974 • 496 citations

Prostaglandins as Potentiators of Increased Vascular Permeability in Inflammation

1973 • 485 citations

Radioimmunoassay of Prostaglandins F_α, E₁ and E₂ in Human Plasma

1975 • 450 citations

Stimulation of human eosinophil and neutrophil polymorphonuclear leukocyte chemotaxis and random migration by 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid.

1977 • 356 citations

Corticosteroids inhibit complement-induced granulocyte aggregation. A possible mechanism for their efficacy in shock states.

1979 • 284 citations

Quantitative determination of prostaglandins and malondialdehyde formed by the arachidonate oxygenase (prostaglandin synthetase) system of bovine seminal vesicle

1973 • 275 citations

Primary structural analysis of the polypeptide portion of human C5a anaphylatoxin. Polypeptide sequence determination and assignment of the oligosaccharide attachment site in C5a.

1978 • 253 citations

Thromboxane generation by human peripheral blood polymorphonuclear leukocytes.

1978 • 229 citations

Application of imidazole as a selective inhibitor thromboxane synthetase in human platelets.

1977 • 215 citations

PROSTAGLANDIN E₁: A POTENTIAL MEDIATOR OF THE INFLAMMATORY RESPONSE

1971 • 203 citations

Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes

1979 • 197 citations

Role of secretory events in modulating human neutrophil chemotaxis.

1978 • 193 citations

Prostaglandin Endoperoxides IX. Characterization of Rabbit Aorta Contracting Substance (RCS) from Guinea Pig Lung and Human Platelets

1975 • 179 citations

Comparative adherence of granulocytes to endothelial monolayers and nylon fiber.

1978 • 169 citations

Neutrophil Aggregation and Swelling Induced by Chemotactic Agents

1977 • 166 citations

STUDIES ON THE PATHOGENESIS OF ACUTE INFLAMMATION

1955 • 165 citations

Effect of Inhibitors of Arachidonic Acid Metabolism on Mitogenesis in Human Lymphocytes: Possible Role of Thromboxanes and Products of the Lipoxygenase Pathway

1979 • 163 citations

A neutrophil chemotatic factor derived from C'5 upon interaction of guinea pig serum with endotoxin.

1969 • 154 citations

Release of prostaglandins from human polymorphonuclear leukocytes

1975 • 121 citations

Modulation of human platelet function by prostacyclin and thromboxane A2.

1979 • 120 citations

Polymorphonuclear leukocytes produce thromboxane A2-like activity during phagocytosis

1976 • 114 citations

Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry

1978 • 114 citations

Thrombin, collagen and A23187 stimulated endogenous platelet arachidonate metabolism: Differential inhibition by PGE1, local anesthetics and a serine-protease inhibitor

1977 • 104 citations

A Neutrophil Chemotactic Factor Derived from C′5 upon Interaction of Guinea Pig Serum with Endotoxin

1969 • 101 citations

Stereoisomeric relationships among anti-inflammatory activity, inhibition of platelet aggregation, and inhibition of prostaglandin synthetase

1975 • 100 citations

On the inhibitory potency of imidazole and its derivatives on thromboxane synthetase

1978 • 98 citations

STUDIES ON THE PATHOGENESIS OF ACUTE INFLAMMATION

1955 • 83 citations

Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes

1978 • 75 citations

A possible role of arachidonic acid in human neutrophil aggregation and degranulation.

1979 • 67 citations

Neutrophil aggregation and degranulation. Effect of arachidonic acid.

1979 • 64 citations

The Effect of 3′,5′-Adenosine Monophosphate on Granulocyte Adhesion

1974 • 63 citations

Studies on the pathogenesis of acute inflammation

1970 • 61 citations

The influence of chemotactic factors on neutrophil adhesiveness

1978 • 47 citations

Effect of prostaglandins E1, E2 and F2α on neutrophil aggregation

1979 • 45 citations

Prostaglandin production by human peripheral blood cells in vitro.

1977 • 44 citations

Chemokinetic and chemotactic activity of various prostaglandins for neutrophil granulocytes

1979 • 29 citations

Adherence of Polymorphonuclear Leukocytes to Nylon: Modulation by Prostacyclin (PGI2), Corticosteroids, and Complement Activation

1980 • 29 citations

Proceedings: Prostaglandin E1 synthesis by phagocytosing rabbit polymorphonuclear leucocytes: its inhibition by indomethacin and its role in chemotaxis.

1973 • 24 citations

A structural requirement for the conversion of prostaglandin endoperoxides to thromboxanes

1979 • 22 citations

Salicylate blockade of granulocyte adherence and the inflammatory response to experimental peritonitis

1979 • 12 citations

Generation of thromboxane A2-like activity from prostaglandin endoperoxides by polymorphonuclear leukocyte homogenates [proceedings].

1976 • 4 citations

The release of thromboxane B2 by rabbit peritoneal polymorphonuclear leucocytes [proceedings].

1978 • 3 citations

In vitro effects of prostaglandins on polymorphonuclear leucocyte function.

1974 • 3 citations

Salicylate blockade of granulocyte adherence and the inflammatory response to experimental peritonitis

1979 • 2 citations