Rapid and simple method for the measurement of methotrexate and 7-hydroxymethotrexate in serum by high-performance liquid chromatography

The clinical pharmacology of methotrexate.new applications of an old drug

1978 • 561 citations

7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate.

1976 • 256 citations

Determination of methotrexate in plasma by on-column concentration and ion-exchange chromatography

1978 • 113 citations

The role of 7-hydroxymethotrexate during methotrexate anti-cancer therapy

1980 • 106 citations

Presence of 2,4‐diamino‐N¹⁰‐methylpteroic acid after high‐dose methotrexate

1979 • 98 citations

Analysis of methotrexate in human plasma by high-pressure liquid chromatography with fluorescence detection.

1977 • 57 citations

Plasma methotrexate as determined by liquid chromatography, enzyme-inhibition assay, and radioimmunoassay after high-dose infusion.

1980 • 49 citations

Development and application of a radioimmunoassay for methotrexate

1977 • 49 citations

Preparation of 125iodine-labelled methotrexate and its use in a magnetisable particle solid-phase radioimmunoassay

1978 • 21 citations

Reversed-phase high-performance liquid chromatographic analysis of methotrexate and 7-hydroxymethotrexate in serum

1980 • 18 citations

METHOTREXATE MEGADOSAGE FOLLOWED BY FOLATE RESCUE I. A STUDY IN CLEARANCE PATTERNS

1962 • 14 citations